STRINGSTRING
ANIA_05982 ANIA_05982 ANIA_04887 ANIA_04887 ANIA_05666 ANIA_05666 ANIA_05588 ANIA_05588 mmm1 mmm1 ANIA_08874 ANIA_08874 ANIA_07771 ANIA_07771 sskA sskA fis1 fis1 ANIA_05660 ANIA_05660 ANIA_05186 ANIA_05186 atg8 atg8 ANIA_04189 ANIA_04189 ANIA_02939 ANIA_02939 atg11 atg11 ANIA_02766 ANIA_02766 mdm34 mdm34 ANIA_02007 ANIA_02007 atg1 atg1 ANIA_01546 ANIA_01546 ANIA_01485 ANIA_01485 ANIA_01272 ANIA_01272 pbsA pbsA ANIA_00914 ANIA_00914 mdm12 mdm12 ANIA_00040 ANIA_00040 mdmB mdmB hog1 hog1 tcsB tcsB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANIA_05982TorA protein; Belongs to the PI3/PI4-kinase family. (2385 aa)
ANIA_04887Mitogen-activated protein (MAP) kinase kinase kinase (Eurofung). (1558 aa)
ANIA_05666Mitogen-activated protein kinase. (330 aa)
ANIA_05588Intermembrane space AAA protease IAP-1 (AFU_orthologue AFUA_4G11530). (784 aa)
mmm1Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The mdm10-mdm12-mmm1 su [...] (472 aa)
ANIA_08874Dynamin-like GTPase Dnm1, putative (AFU_orthologue AFUA_8G02840); Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (794 aa)
ANIA_07771Uncharacterized protein. (188 aa)
sskACytoplasmic response regulator (Eurofung). (838 aa)
fis1Mitochondrial fission 1 protein; Has a role in mitochondrial fission. Has a role in outer membrane fission but not matrix separation (By similarity). (153 aa)
ANIA_05660Putative plasma membrane sensor transducer (Eurofung). (280 aa)
ANIA_05186Ubiquitin carboxyl-terminal hydrolase. (840 aa)
atg8Autophagy-related protein 8; Ubiquitin-like modifier involved in autophagosomes formation. With atg4, mediates the delivery of the autophagosomes to the vacuole via the microtubule cytoskeleton. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Participates also in membrane fusion events that take place in the early secretory pathway. Also involved [...] (118 aa)
ANIA_04189Putative MAPKK (Eurofung). (502 aa)
ANIA_02939MRS7 family protein (AFU_orthologue AFUA_3G08230). (543 aa)
atg11Autophagy-related protein 11; Involved in cytoplasm to vacuole transport (Cvt), pexophagy, mitophagy and nucleophagy. Recruits mitochondria for their selective degradation via autophagy (mitophagy) during starvation. Works as scaffold proteins that recruit ATG proteins to the pre-autophagosome (PAS), the site of vesicle/autophagosome formation. Required for the Cvt vesicles completion (By similarity). (1285 aa)
ANIA_02766Multicopy suppressor of stt4 mutation (AFU_orthologue AFUA_3G06080). (841 aa)
mdm34Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm34 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. (561 aa)
ANIA_02007Small nuclear ribonucleoprotein Sm D3. (116 aa)
atg1Serine/threonine-protein kinase atg1; Serine/threonine protein kinase involved in the cytoplasm to vacuole transport (Cvt) and found to be essential in autophagy, where it is required for the formation of autophagosomes. Involved in the clearance of protein aggregates which cannot be efficiently cleared by the proteasome. Required for selective autophagic degradation of the nucleus (nucleophagy) as well as for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing [...] (935 aa)
ANIA_01546Transcription factor (Sin3), putative (AFU_orthologue AFUA_8G05570). (1605 aa)
ANIA_01485Casein kinase II (Eurofung); Belongs to the protein kinase superfamily. (333 aa)
ANIA_01272Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (264 aa)
pbsAMAP kinase kinase (Eurofung). (651 aa)
ANIA_00914Protein phosphatase 2C, putative (AFU_orthologue AFUA_1G15800). (560 aa)
mdm12Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. Mdm12 is required for the interaction of the ER-resident membrane protein mmm1 and the outer mitochondrial membrane-resident beta-barrel protein mdm10. The mdm12-mmm1 subcomplex functions in the major beta-barrel assembly pat [...] (436 aa)
ANIA_00040DNA polymerase gamma (AFU_orthologue AFUA_5G12640). (1134 aa)
mdmBMitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. mdm10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the tom40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of tom40 with the recepto [...] (427 aa)
hog1Mitogen-activated protein kinase hog1; Mitogen-activated protein kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment. Controls osmotic regulation of transcription of target genes; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. HOG1 sub-subfamily. (379 aa)
tcsBTwo-component system protein B; Nonessential protein which may be part of a two-component regulatory system activated by changes in the extracellular environment. (1065 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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