STRINGSTRING
ANIA_03592 ANIA_03592 ANIA_04031 ANIA_04031 ANIA_11054 ANIA_11054 ANIA_10556 ANIA_10556 ANIA_07360 ANIA_07360 ANIA_07704 ANIA_07704 ANIA_10702 ANIA_10702 ANIA_03449 ANIA_03449 ANIA_03080 ANIA_03080 ANIA_02731 ANIA_02731 ANIA_01455 ANIA_01455 ANIA_02304 ANIA_02304 ANIA_00819 ANIA_00819 ANIA_01019 ANIA_01019 ANIA_00248 ANIA_00248 ANIA_00235 ANIA_00235 ANIA_03566 ANIA_03566 cfd1 cfd1 ANIA_08844 ANIA_08844 ANIA_08269 ANIA_08269 ANIA_08258 ANIA_08258 ANIA_07721 ANIA_07721 ANIA_07472 ANIA_07472 ANIA_07436 ANIA_07436 ANIA_07426 ANIA_07426 ANIA_07338 ANIA_07338 ANIA_07321 ANIA_07321 ANIA_07302 ANIA_07302 cdc48 cdc48 ANIA_06606 ANIA_06606 fes1 fes1 ANIA_06307 ANIA_06307 ANIA_06269 ANIA_06269 sec31 sec31 ANIA_06170 ANIA_06170 ANIA_06136 ANIA_06136 ANIA_05900 ANIA_05900 ANIA_05748 ANIA_05748 ANIA_05451 ANIA_05451 hsp70 hsp70 ANIA_04683 ANIA_04683 ANIA_04623 ANIA_04623 ANIA_04589 ANIA_04589 ANIA_04441 ANIA_04441 sec13 sec13 png1 png1 ANIA_03733 ANIA_03733 sec24 sec24 ANIA_03463 ANIA_03463 ANIA_03156 ANIA_03156 ANIA_02761 ANIA_02761 sconC sconC ANIA_02246 ANIA_02246 ANIA_02062 ANIA_02062 ANIA_02045 ANIA_02045 ANIA_01683 ANIA_01683 ANIA_01488 ANIA_01488 yos9 yos9 ANIA_00847 ANIA_00847 ANIA_00834 ANIA_00834 ANIA_00810 ANIA_00810 mns1B mns1B ANIA_00551 ANIA_00551 ANIA_00417 ANIA_00417 sar1 sar1 ANIA_00329 ANIA_00329 npl4 npl4 sec23 sec23 ANIA_00075 ANIA_00075
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANIA_03592Calnexin, putative (Eurofung). (561 aa)
ANIA_04031Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (170 aa)
ANIA_11054Alpha glucosidase II, alpha subunit, putative (AFU_orthologue AFUA_5G03500); Belongs to the glycosyl hydrolase 31 family. (952 aa)
ANIA_10556Ubiquitin chain assembly factor (Eurofung). (1095 aa)
ANIA_07360DnaJ domain protein (Mas5), putative (AFU_orthologue AFUA_2G16290). (402 aa)
ANIA_07704Polyubiquitin binding protein (Doa1/Ufd3), putative (AFU_orthologue AFUA_5G08370). (811 aa)
ANIA_10702Protein kinase C substrate, putative (AFU_orthologue AFUA_7G04110). (567 aa)
ANIA_03449OTU-like cysteine protease, putative (AFU_orthologue AFUA_3G05550). (323 aa)
ANIA_03080Vesicle coat complex COPII, subunit Sec24 family protein, putative (Eurofung). (1031 aa)
ANIA_02731Protein mitochondrial targeting protein (Mas1), putative (AFU_orthologue AFUA_1G05040). (412 aa)
ANIA_01455Uncharacterized protein. (741 aa)
ANIA_02304UV excision repair protein (RadW), putative (AFU_orthologue AFUA_5G06040). (369 aa)
ANIA_00819BAP31 domain protein, putative (AFU_orthologue AFUA_1G14780). (215 aa)
ANIA_01019SCF ubiquitin ligase complex subunit CulA, putative (AFU_orthologue AFUA_1G12960); Belongs to the cullin family. (764 aa)
ANIA_00248PDI related protein A (Eurofung). (455 aa)
ANIA_00235Serine-threonine kinase and endoribonuclease (Eurofung). (1121 aa)
ANIA_03566alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (586 aa)
cfd1Cytosolic Fe-S cluster assembly factor cfd1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The nbp35-cfd1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (334 aa)
ANIA_08844RING-box protein 1 (Broad). (116 aa)
ANIA_08269Heat shock protein 90 (Eurofung). (700 aa)
ANIA_08258Ubiquitin conjugating enzyme (UbcH), putative (AFU_orthologue AFUA_5G04060); Belongs to the ubiquitin-conjugating enzyme family. (166 aa)
ANIA_07721Plug_translocon domain-containing protein. (478 aa)
ANIA_07472Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (502 aa)
ANIA_07436Protein disulfide-isomerase. (513 aa)
ANIA_07426Oligosaccharyl transferase subunit (Gamma), putative (AFU_orthologue AFUA_2G06280). (127 aa)
ANIA_07338Ubiquitin conjugating enzyme (UbcF), putative (AFU_orthologue AFUA_2G16470). (334 aa)
ANIA_07321Protein kinase, putative (AFU_orthologue AFUA_2G16620). (756 aa)
ANIA_07302Lectin family integral membrane protein, putative (AFU_orthologue AFUA_2G16800). (419 aa)
cdc48Cell division control protein 48; Involved in spindle disassembly, degradation of ubiquitinated proteins and protein export from the endoplasmic reticulum to the cytoplasm. Acts as a chaperone that collects ubiquitinated substrates. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. Cdc48 may provide the mechanical force that dislodges the polyubiquitinated n [...] (823 aa)
ANIA_06606Mannosyl-oligosaccharide glucosidase, putative (AFU_orthologue AFUA_6G04210). (749 aa)
fes1Hsp70 nucleotide exchange factor fes1; Functions as a nucleotide exchange factor (NEF) for Hsp70 chaperones which accelerates the release of ADP. Required for fully efficient Hsp70-mediated folding of proteins (By similarity). Belongs to the FES1 family. (218 aa)
ANIA_06307Lectin family integral membrane protein, putative (AFU_orthologue AFUA_2G12180). (360 aa)
ANIA_06269Translocation protein sec62 (Eurofung). (394 aa)
sec31Protein transport protein sec31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1282 aa)
ANIA_06170DnaJ domain protein, putative (AFU_orthologue AFUA_2G08300). (418 aa)
ANIA_06136RING finger membrane protein (AFU_orthologue AFUA_2G08650). (1573 aa)
ANIA_05900AMFR protein, putative (AFU_orthologue AFUA_2G11100). (197 aa)
ANIA_05748alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (708 aa)
ANIA_05451Ubiquitin-like protein DskB, putative (AFU_orthologue AFUA_6G13420). (440 aa)
hsp70Heat shock 70 kDa protein; Involved in osmoadaptation; Belongs to the heat shock protein 70 family. (644 aa)
ANIA_04683Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (460 aa)
ANIA_04623UDP-glucose-glycoprotein glucosyltransferase (Eurofung). (1483 aa)
ANIA_04589Protein translocation complex subunit Sss1, putative (AFU_orthologue AFUA_3G06901). (70 aa)
ANIA_04441ER associated DnaJ chaperone (Hlj1), putative (AFU_orthologue AFUA_4G07330). (339 aa)
sec13Protein transport protein sec13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (309 aa)
png1Protein PNG1; Belongs to the transglutaminase-like superfamily. PNGase family. (441 aa)
ANIA_03733alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (816 aa)
sec24Protein transport protein sec24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (908 aa)
ANIA_03463DnaJ and TPR domain protein (AFU_orthologue AFUA_3G05400). (519 aa)
ANIA_03156Translation initiation factor eIF2 alpha subunit (Eurofung). (308 aa)
ANIA_02761UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (147 aa)
sconCE3 ubiquitin ligase complex SCF subunit sconC; Essential component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Controls sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor. (161 aa)
ANIA_02246eIF2 alpha kinase (Eurofung). (1552 aa)
ANIA_02062Uncharacterized protein; Belongs to the heat shock protein 70 family. (674 aa)
ANIA_02045alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (598 aa)
ANIA_01683Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (290 aa)
ANIA_01488RING finger protein (AFU_orthologue AFUA_8G04840). (775 aa)
yos9Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity). (509 aa)
ANIA_00847Molecular chaperone (Eurofung). (996 aa)
ANIA_00834Protein translocation complex componenet (Npl1), putative (AFU_orthologue AFUA_1G14940). (696 aa)
ANIA_00810Ubiquitin-protein ligase Sel1/Ubx2, putative (AFU_orthologue AFUA_1G14690). (1121 aa)
mns1BMannosyl-oligosaccharide alpha-1,2-mannosidase 1B; Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). (505 aa)
ANIA_00551alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (584 aa)
ANIA_00417Translocon protein Sec61beta, putative (AFU_orthologue AFUA_1G04890). (250 aa)
sar1Small COPII coat GTPase sar1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated sar1-GTP binds to membranes first and recruits the sec23/24 complex. These sec23/24-sar1 prebudding intermediates are then collected by the Sec13/31 complex as subunits polymerize to form coated trans [...] (189 aa)
ANIA_00329Ubiquitin fusion degradation protein Ufd1, putative (AFU_orthologue AFUA_1G02430). (393 aa)
npl4Nuclear protein localization protein 4; Involved in the import of nuclear-targeted proteins into the nucleus and the export of poly(A) RNA out of the nucleus. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway (By similarity); Belongs to the NPL4 family. (652 aa)
sec23Protein transport protein sec23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (771 aa)
ANIA_00075Protein disulfide-isomerase (Eurofung); Belongs to the protein disulfide isomerase family. (368 aa)
Your Current Organism:
Aspergillus nidulans
NCBI taxonomy Id: 227321
Other names: A. nidulans FGSC A4, Aspergillus nidulans FGSC A4, Emericella nidulans FGSC A4
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