(12 nodes) Novobiocin biosynthesis, and Beta-eliminating lyase network (Hyphomonas neptunium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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protein homology

Your Input:
	HNE_0095	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409. (387 aa)
	HNE_0613	Decarboxylase, group II; Identified by match to protein family HMM PF00282. (494 aa)
	HNE_0652	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. (396 aa)
	HNE_0659	Prephenate dehydratase; Identified by match to protein family HMM PF00800. (278 aa)
	tnaA	Identified by match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family. (454 aa)
	hisC	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (367 aa)
	HNE_2357	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. (384 aa)
	dadA	D-amino acid dehydrogenase, small subunit; Identified by similarity to SP:P29011; match to protein family HMM PF01266. (410 aa)
	hppD	4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM TIGR01263. (366 aa)
	aatA	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155. (403 aa)
	HNE_3117	Putative D-alanine aminotransferase; Identified by match to protein family HMM PF01063. (296 aa)
	HNE_3400	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807. (313 aa)

Your Current Organism:

Hyphomonas neptunium

NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HNE_0095	HNE_0613	HNE_0095	HNE_0613	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	0.902
HNE_0095	HNE_0652	HNE_0095	HNE_0652	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.911
HNE_0095	HNE_0659	HNE_0095	HNE_0659	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	0.912
HNE_0095	HNE_2357	HNE_0095	HNE_2357	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.918
HNE_0095	HNE_3117	HNE_0095	HNE_3117	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Putative D-alanine aminotransferase; Identified by match to protein family HMM PF01063.	0.916
HNE_0095	HNE_3400	HNE_0095	HNE_3400	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.966
HNE_0095	aatA	HNE_0095	HNE_2968	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.	0.919
HNE_0095	dadA	HNE_0095	HNE_2416	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	D-amino acid dehydrogenase, small subunit; Identified by similarity to SP:P29011; match to protein family HMM PF01266.	0.901
HNE_0095	hisC	HNE_0095	HNE_1125	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.926
HNE_0095	hppD	HNE_0095	HNE_2900	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	4-hydroxyphenylpyruvate dioxygenase; Identified by similarity to SP:P80064; match to protein family HMM PF00903; match to protein family HMM TIGR01263.	0.905
HNE_0095	tnaA	HNE_0095	HNE_0810	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Identified by match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family.	0.900
HNE_0613	HNE_0095	HNE_0613	HNE_0095	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	0.902
HNE_0613	HNE_0652	HNE_0613	HNE_0652	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.908
HNE_0613	HNE_0659	HNE_0613	HNE_0659	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	0.808
HNE_0613	HNE_2357	HNE_0613	HNE_2357	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.902
HNE_0613	HNE_3400	HNE_0613	HNE_3400	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.803
HNE_0613	aatA	HNE_0613	HNE_2968	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.	0.907
HNE_0613	hisC	HNE_0613	HNE_1125	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.902
HNE_0613	tnaA	HNE_0613	HNE_0810	Decarboxylase, group II; Identified by match to protein family HMM PF00282.	Identified by match to protein family HMM PF01212; Belongs to the beta-eliminating lyase family.	0.904
HNE_0652	HNE_0095	HNE_0652	HNE_0095	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	0.911

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