(6 nodes) Novobiocin biosynthesis network (Hyphomonas neptunium)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	HNE_0095	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409. (387 aa)
	HNE_0659	Prephenate dehydratase; Identified by match to protein family HMM PF00800. (278 aa)
	hisC	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (367 aa)
	HNE_2357	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155. (384 aa)
	aatA	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155. (403 aa)
	HNE_3400	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807. (313 aa)

Your Current Organism:

Hyphomonas neptunium

NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HNE_0095	HNE_0659	HNE_0095	HNE_0659	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	0.912
HNE_0095	HNE_2357	HNE_0095	HNE_2357	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.918
HNE_0095	HNE_3400	HNE_0095	HNE_3400	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.966
HNE_0095	aatA	HNE_0095	HNE_2968	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.	0.919
HNE_0095	hisC	HNE_0095	HNE_1125	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.926
HNE_0659	HNE_0095	HNE_0659	HNE_0095	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	0.912
HNE_0659	HNE_2357	HNE_0659	HNE_2357	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.912
HNE_0659	HNE_3400	HNE_0659	HNE_3400	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.968
HNE_0659	aatA	HNE_0659	HNE_2968	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.	0.990
HNE_0659	hisC	HNE_0659	HNE_1125	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.912
HNE_2357	HNE_0095	HNE_2357	HNE_0095	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	0.918
HNE_2357	HNE_0659	HNE_2357	HNE_0659	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	0.912
HNE_2357	HNE_3400	HNE_2357	HNE_3400	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	0.967
HNE_2357	aatA	HNE_2357	HNE_2968	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.	0.926
HNE_2357	hisC	HNE_2357	HNE_1125	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.926
HNE_3400	HNE_0095	HNE_3400	HNE_0095	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155; match to protein family HMM TIGR01409.	0.966
HNE_3400	HNE_0659	HNE_3400	HNE_0659	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	Prephenate dehydratase; Identified by match to protein family HMM PF00800.	0.968
HNE_3400	HNE_2357	HNE_3400	HNE_2357	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	Aminotransferase, classes I and II; Identified by match to protein family HMM PF00155.	0.967
HNE_3400	aatA	HNE_3400	HNE_2968	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	Aspartate aminotransferase; Identified by similarity to SP:Q02635; match to protein family HMM PF00155.	0.909
HNE_3400	hisC	HNE_3400	HNE_1125	Prephenate dehydrogenase; Identified by match to protein family HMM PF01408; match to protein family HMM PF02153; match to protein family HMM PF03446; match to protein family HMM PF03807.	Histidinol-phosphate aminotransferase; Identified by similarity to SP:P17731; match to protein family HMM PF00155; match to protein family HMM TIGR01141; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.	0.976

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