(21 nodes) Prosthetic group metabolic process, and [2Fe-2S]-binding network (Hyphomonas neptunium)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Your Input:
	HNE_1064	Putative membrane protein; Identified by match to protein family HMM PF01925. (256 aa)
	moaC1	Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (161 aa)
	moaB1	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (176 aa)
	moaE1	Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391. (153 aa)
	HNE_1068	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597. (82 aa)
	moaA1	Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (343 aa)
	HNE_1070	Putative xanthine dehydrogenase accessory factor; Identified by match to protein family HMM PF02625. (513 aa)
	HNE_1071	Putative xanthine dehydrogenase, molybdenum-binding subunit; Identified by similarity to SP:P77489; match to protein family HMM PF01315; match to protein family HMM PF02738. (731 aa)
	HNE_1072	Putative xanthine dehydrogenase, FAD-binding subunit; Identified by similarity to SP:P77324; match to protein family HMM PF00941. (316 aa)
	HNE_1073	Putative xanthine dehydrogenase, iron-sulfur binding subunit; Identified by similarity to SP:P77165; match to protein family HMM PF00111; match to protein family HMM PF01799. (216 aa)
	HNE_1548	Putative molybdopterin converting factor; Identified by match to protein family HMM PF02597. (79 aa)
	moaE2	Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391. (165 aa)
	moaB2	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (178 aa)
	moaC2	Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (162 aa)
	moeA1	Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (394 aa)
	moaA2	Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (330 aa)
	moeA2	Molybdopterin biosynthesis protein MoeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (398 aa)
	HNE_2200	Putative isoquinoline 1-oxidoreductase, alpha subunit; Identified by similarity to SP:Q51697; match to protein family HMM PF00111; match to protein family HMM PF01799. (152 aa)
	HNE_2201	Conserved hypothetical protein. (240 aa)
	HNE_2202	Putative isoquinoline 1-oxidoreductase, beta subunit; Identified by similarity to SP:Q51698; match to protein family HMM PF01315. (709 aa)
	HNE_3431	Putative molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237. (246 aa)

Your Current Organism:

Hyphomonas neptunium

NCBI taxonomy Id: 228405
Other names: H. neptunium ATCC 15444, Hyphomonas neptunium ATCC 15444, Hyphomonas neptunium str. ATCC 15444, Hyphomonas neptunium strain ATCC 15444

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
HNE_1064	HNE_1068	HNE_1064	HNE_1068	Putative membrane protein; Identified by match to protein family HMM PF01925.	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	0.784
HNE_1064	HNE_1070	HNE_1064	HNE_1070	Putative membrane protein; Identified by match to protein family HMM PF01925.	Putative xanthine dehydrogenase accessory factor; Identified by match to protein family HMM PF02625.	0.789
HNE_1064	HNE_1071	HNE_1064	HNE_1071	Putative membrane protein; Identified by match to protein family HMM PF01925.	Putative xanthine dehydrogenase, molybdenum-binding subunit; Identified by similarity to SP:P77489; match to protein family HMM PF01315; match to protein family HMM PF02738.	0.773
HNE_1064	HNE_1072	HNE_1064	HNE_1072	Putative membrane protein; Identified by match to protein family HMM PF01925.	Putative xanthine dehydrogenase, FAD-binding subunit; Identified by similarity to SP:P77324; match to protein family HMM PF00941.	0.773
HNE_1064	HNE_1073	HNE_1064	HNE_1073	Putative membrane protein; Identified by match to protein family HMM PF01925.	Putative xanthine dehydrogenase, iron-sulfur binding subunit; Identified by similarity to SP:P77165; match to protein family HMM PF00111; match to protein family HMM PF01799.	0.773
HNE_1064	moaA1	HNE_1064	HNE_1069	Putative membrane protein; Identified by match to protein family HMM PF01925.	Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.	0.813
HNE_1064	moaB1	HNE_1064	HNE_1066	Putative membrane protein; Identified by match to protein family HMM PF01925.	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.	0.778
HNE_1064	moaC1	HNE_1064	HNE_1065	Putative membrane protein; Identified by match to protein family HMM PF01925.	Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family.	0.778
HNE_1064	moaE1	HNE_1064	HNE_1067	Putative membrane protein; Identified by match to protein family HMM PF01925.	Molybdopterin converting factor, subunit 2; Identified by similarity to SP:P30749; match to protein family HMM PF02391.	0.778
HNE_1068	HNE_1064	HNE_1068	HNE_1064	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative membrane protein; Identified by match to protein family HMM PF01925.	0.784
HNE_1068	HNE_1070	HNE_1068	HNE_1070	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative xanthine dehydrogenase accessory factor; Identified by match to protein family HMM PF02625.	0.869
HNE_1068	HNE_1071	HNE_1068	HNE_1071	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative xanthine dehydrogenase, molybdenum-binding subunit; Identified by similarity to SP:P77489; match to protein family HMM PF01315; match to protein family HMM PF02738.	0.792
HNE_1068	HNE_1072	HNE_1068	HNE_1072	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative xanthine dehydrogenase, FAD-binding subunit; Identified by similarity to SP:P77324; match to protein family HMM PF00941.	0.785
HNE_1068	HNE_1073	HNE_1068	HNE_1073	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative xanthine dehydrogenase, iron-sulfur binding subunit; Identified by similarity to SP:P77165; match to protein family HMM PF00111; match to protein family HMM PF01799.	0.790
HNE_1068	HNE_1548	HNE_1068	HNE_1548	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative molybdopterin converting factor; Identified by match to protein family HMM PF02597.	0.900
HNE_1068	HNE_3431	HNE_1068	HNE_3431	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Putative molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00899; match to protein family HMM PF05237.	0.973
HNE_1068	moaA1	HNE_1068	HNE_1069	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.	0.899
HNE_1068	moaA2	HNE_1068	HNE_1557	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Molybdenum cofactor biosynthesis protein MoaA; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate.	0.573
HNE_1068	moaB1	HNE_1068	HNE_1066	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.	0.889
HNE_1068	moaB2	HNE_1068	HNE_1551	Putative molybdopterin converting factor, subunit 1; Identified by match to protein family HMM PF02597.	Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.	0.532

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