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| | mreB | Rod shape-determining protein MreB; Identified by match to protein family HMM PF06723; match to protein family HMM TIGR00904. (346 aa) |
| | HNE_2924 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (637 aa) |
| | HNE_2920 | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAS95092.1; match to protein family HMM PF00005. (255 aa) |
| | carA | Carbamoyl-phosphate synthase, small subunit; Identified by match to protein family HMM PF00117; match to protein family HMM PF00988; match to protein family HMM TIGR01368; Belongs to the CarA family. (386 aa) |
| | HNE_2877 | Hypothetical protein; Identified by Glimmer2; putative. (312 aa) |
| | adk | Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (189 aa) |
| | ttcA | PP-loop family protein; Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine/cysteine desulfurase (IscS) system. (295 aa) |
| | uvrA | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (992 aa) |
| | gyrA | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (926 aa) |
| | coaD | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (165 aa) |
| | HNE_2744 | Conserved hypothetical protein. (273 aa) |
| | recA | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (356 aa) |
| | alaS | alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (881 aa) |
| | argS | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. (589 aa) |
| | pckA | Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (530 aa) |
| | HNE_2695 | Iron ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005; Belongs to the ABC transporter superfamily. (335 aa) |
| | HNE_2681 | Conserved hypothetical protein; Identified by similarity to PIR:D95989; match to protein family HMM PF04169; match to protein family HMM PF04174. (475 aa) |
| | HNE_2676 | Hypothetical protein; Identified by Glimmer2; putative. (227 aa) |
| | HNE_2669 | Identified by match to protein family HMM PF02562. (269 aa) |
| | HNE_2642 | ATPase, AAA family; Identified by match to protein family HMM PF00004. (436 aa) |
| | HNE_2636 | Conserved hypothetical protein. (255 aa) |
| | tyrS | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (416 aa) |
| | anmK | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (387 aa) |
| | sufC | FeS assembly ATPase SufC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978. (253 aa) |
| | HNE_2613 | Conserved hypothetical protein; Identified by similarity to GB:AAN29861.1; match to protein family HMM PF01883; match to protein family HMM TIGR02945. (127 aa) |
| | purS | Phosphoribosylformylglycinamidine synthase PurS; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assis [...] (80 aa) |
| | purC | Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to protein family HMM PF01259; match to protein family HMM TIGR00081; Belongs to the SAICAR synthetase family. (259 aa) |
| | HNE_2602 | Identified by match to protein family HMM PF01812; match to protein family HMM TIGR02727; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (207 aa) |
| | HNE_2598 | AMP-binding enzyme; Identified by match to protein family HMM PF00501. (952 aa) |
| | gltX2 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (445 aa) |
| | nadE | Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (555 aa) |
| | vlacs | Very-long-chain acyl-CoA synthetase; Identified by similarity to SP:P97524; match to protein family HMM PF00501. (596 aa) |
| | HNE_2569 | alpha-L-glutamate ligase family protein. (489 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (371 aa) |
| | HNE_2551 | UvrD/REP helicase domain protein; Identified by match to protein family HMM PF00580; match to protein family HMM PF06114; Belongs to the helicase family. UvrD subfamily. (1137 aa) |
| | HNE_2539 | Type I restriction-modification system, R subunit; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04313; match to protein family HMM PF04851. (1134 aa) |
| | HNE_2538 | Conserved hypothetical protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (188 aa) |
| | HNE_2517 | Type II secretion system protein; Identified by match to protein family HMM PF00437. (540 aa) |
| | HNE_2503 | Identified by similarity to SP:Q01262; match to protein family HMM PF01968; match to protein family HMM PF05378. (528 aa) |
| | phnC | Phosphonate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphonates importer (TC 3.A.1.9.1) family. (261 aa) |
| | phnD | Phosphonate ABC transporter, periplasmic phosphonate-binding protein; Identified by match to protein family HMM TIGR01098. (307 aa) |
| | fcs4 | feruloyl-CoA synthetase; Identified by similarity to GB:CAC18323.1; match to protein family HMM PF00501. (565 aa) |
| | HNE_2419 | Kinase, PfkB family; Identified by match to protein family HMM PF00294. (315 aa) |
| | folK | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498. (166 aa) |
| | HNE_2337 | Conserved domain protein. (281 aa) |
| | HNE_2308 | Identified by match to protein family HMM PF00501. (515 aa) |
| | gatC | glutamyl-tRNA(Gln) amidotransferase, C subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | gatA | glutamyl-tRNA(Gln) amidotransferase, A subunit; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (490 aa) |
| | gatB | glutamyl-tRNA(Gln) amidotransferase, B subunit; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (502 aa) |
| | ndk | Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (140 aa) |
| | purM | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. (342 aa) |
| | HNE_2261 | Conserved hypothetical protein; Identified by similarity to GB:BAB53627.1. (243 aa) |
| | ppk | Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (725 aa) |
| | aspS | aspartyl-tRNA synthetase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (609 aa) |
| | accC | acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (457 aa) |
| | HNE_2241 | Putative chain length determinant protein; Identified by match to protein family HMM PF02706. (473 aa) |
| | HNE_2240 | Conserved hypothetical protein. (231 aa) |
| | HNE_2237 | Carbohydrate kinase, FGGY family; Identified by match to protein family HMM PF00069; match to protein family HMM PF00481. (574 aa) |
| | dnaB | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (496 aa) |
| | gmk | Putative guanylate kinase; Essential for recycling GMP and indirectly, cGMP. (217 aa) |
| | HNE_2144 | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069; match to protein family HMM PF00515; match to protein family HMM PF07721. (803 aa) |
| | HNE_2140 | Conserved hypothetical protein. (583 aa) |
| | HNE_2125 | LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (250 aa) |
| | HNE_2124 | Allophanate hydrolase, subunit 1; Identified by match to protein family HMM PF02682. (209 aa) |
| | pyk | Pyruvate kinase; Identified by similarity to SP:P70789; match to protein family HMM PF00224; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. (474 aa) |
| | HNE_2123 | Allophanate hydrolase, subunit 2; Identified by match to protein family HMM PF02626; match to protein family HMM TIGR00724. (309 aa) |
| | clpX | ATP-dependent Clp protease, ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (420 aa) |
| | ppnK | ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (255 aa) |
| | nrdR | Transcriptional regulator, NrdR family; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (159 aa) |
| | HNE_2037 | Conserved hypothetical protein; Identified by similarity to GB:AAK25694.1. (292 aa) |
| | hslU | Heat shock protein HslVU, ATPase subunit HslU; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (434 aa) |
| | pstB | Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family. (275 aa) |
| | aas | 2-acylglycerophosphoethanolamine acyltransferase/Acyl-[acyl-carrier-protein] synthetase; Identified by similarity to SP:P31119; match to protein family HMM PF00501. (528 aa) |
| | glnL | Nitrogen regulation protein NR(II); Identified by similarity to SP:P45670; match to protein family HMM PF00512; match to protein family HMM PF02518. (352 aa) |
| | glnG | Nitrogen regulation protein NR(I); Identified by similarity to SP:P06713; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (457 aa) |
| | ntrX | Sigma-54 dependent DNA-binding response regulator; Identified by similarity to SP:Q06065; match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (461 aa) |
| | HNE_1987 | Putative ATP-dependent DNA helicase recG; Identified by similarity to SP:P24230; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF01336. (692 aa) |
| | mfd | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1145 aa) |
| | groL | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (547 aa) |
| | groES | Chaperonin, 10 kDa; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (96 aa) |
| | purL | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] (753 aa) |
| | purQ | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (222 aa) |
| | serS | seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (432 aa) |
| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa) |
| | HNE_1923 | Hypothetical protein; Identified by Glimmer2; putative. (304 aa) |
| | smc | Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1153 aa) |
| | HNE_1899 | ATPase, AAA family; Identified by match to protein family HMM PF07728. (330 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (732 aa) |
| | atpA | ATP synthase F1, alpha subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (511 aa) |
| | atpG | ATP synthase F1, gamma subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (292 aa) |
| | atpD | ATP synthase F1, beta subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (475 aa) |
| | atpC | ATP synthase F1, epsilon subunit; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | HNE_1887 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:AAK25496.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. (151 aa) |
| | addA | Double-strand break repair helicase AddA; Identified by match to protein family HMM PF00580; match to protein family HMM TIGR02784; Belongs to the helicase family. UvrD subfamily. (1168 aa) |
| | HNE_1881 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (313 aa) |
| | gspE | General secretory pathway protein E; Identified by match to protein family HMM PF00437; match to protein family HMM TIGR02533. (496 aa) |
| | fcs3 | feruloyl-CoA synthetase; Identified by similarity to GB:CAC18323.1; match to protein family HMM PF00501. (583 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (579 aa) |
| | tmk | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (219 aa) |
| | guaA | GMP synthase; Catalyzes the synthesis of GMP from XMP. (526 aa) |
| | rfaE | rfaE bifunctional protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (486 aa) |
| | pyrG | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | gltX1 | glutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (486 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (251 aa) |
| | lolD | Lipoprotein releasing system, ATP-binding protein, homolog; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. (228 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro); Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 2 subfamily. (439 aa) |
| | coaX | Putative transcriptional activator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (255 aa) |
| | glk | Glucokinase; Identified by similarity to SP:P46880; match to protein family HMM PF02685; Belongs to the bacterial glucokinase family. (322 aa) |
| | HNE_1725 | Putative helicase; Identified by match to protein family HMM PF00271. (391 aa) |
| | cadA | Cadmium-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01512; match to protein family HMM TIGR01525. (663 aa) |
| | HNE_1700 | Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF04945; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525. (796 aa) |
| | valS | valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (906 aa) |
| | HNE_1670 | Putative DNA ligase, ATP-dependent; Identified by similarity to SP:Q9HHC4; match to protein family HMM PF01068; match to protein family HMM PF04679. (532 aa) |
| | HNE_1662 | Hypothetical protein; Identified by Glimmer2; putative. (318 aa) |
| | HNE_1661 | Putative amino acid ABC transporter, ATP-binding protein CydC; Identified by similarity to SP:P23886; match to protein family HMM PF00005. (546 aa) |
| | HNE_1660 | Amino acid ABC transporter, permease/ATP-binding protein CydD, putaive; Identified by similarity to SP:P29018; match to protein family HMM PF00005; match to protein family HMM TIGR02857. (559 aa) |
| | macB | Putative macrolide efflux ABC transporter, permease/ATP-binding protein; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (645 aa) |
| | HNE_1643 | Aspartate kinase; Identified by match to protein family HMM PF00696; match to protein family HMM PF01842. (482 aa) |
| | HNE_1636 | Protein kinase; Identified by match to protein family HMM PF00069. (438 aa) |
| | HNE_1631 | Protein kinase; Identified by match to protein family HMM PF00069. (792 aa) |
| | HNE_1599 | Hypothetical protein; Identified by Glimmer2; putative. (485 aa) |
| | HNE_1593 | Putative AMP binding protein; Identified by match to protein family HMM PF00501. (591 aa) |
| | HNE_1534 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (575 aa) |
| | HNE_1532 | Fic family protein; Identified by match to protein family HMM PF02661. (263 aa) |
| | cobU | Cobinamide kinase / cobinamide phosphate guanyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (168 aa) |
| | HNE_1517 | Iron compound ABC transporter, ATP-binding protein; Identified by similarity to SP:P07821; match to protein family HMM PF00005. (253 aa) |
| | cobO | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (200 aa) |
| | HNE_1496 | Serine/threonine protein kinase; Identified by match to protein family HMM PF00069. (828 aa) |
| | HNE_1483 | Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00702; match to protein family HMM PF04945; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525. (796 aa) |
| | HNE_1482 | Conserved hypothetical protein; Identified by similarity to GB:CAI09940.1. (444 aa) |
| | acsA | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (648 aa) |
| | HNE_1374 | Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). Belongs to the glutamate--cysteine ligase type 2 family. EgtA subfamily. (458 aa) |
| | HNE_1366 | Efflux ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. (608 aa) |
| | glpK | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (493 aa) |
| | glnE | Glutamate ammonia ligase adenylyl-transferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal trans [...] (919 aa) |
| | mccA | methylcrotonoyl-CoA carboxylase alpha chain; Identified by similarity to SP:Q42523; match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786. (633 aa) |
| | bioD | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. (222 aa) |
| | HNE_1242 | Efflux ABC transporter, heavy metal transporter (HMT) family (ABCB), permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. (618 aa) |
| | HNE_1236 | Response regulator; Identified by match to protein family HMM PF00072. (136 aa) |
| | fixL | Sensory box sensor histidine kinase FixL; Identified by similarity to SP:P26489; match to protein family HMM PF00512; match to protein family HMM PF00989; match to protein family HMM PF02518; match to protein family HMM TIGR00229. (388 aa) |
| | HNE_1226 | Copper-translocating P-type ATPase; Identified by match to protein family HMM PF00122; match to protein family HMM PF00403; match to protein family HMM PF00702; match to protein family HMM TIGR01494; match to protein family HMM TIGR01511; match to protein family HMM TIGR01525. (739 aa) |
| | HNE_1220 | Identified by match to protein family HMM PF01425. (506 aa) |
| | HNE_1219 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (554 aa) |
| | HNE_1205 | ATPase, AAA family; Identified by match to protein family HMM PF07726; match to protein family HMM PF07728. (318 aa) |
| | HNE_1194 | Chain length determinant family protein; Identified by match to protein family HMM PF02706. (801 aa) |
| | thiL | Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (317 aa) |
| | accA | acetyl-CoA carboxylase, carboxyl transferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (318 aa) |
| | HNE_1153 | Type II/IV secretion system protein; Identified by similarity to GB:AAF40195.1; match to protein family HMM PF00437. (462 aa) |
| | HNE_1152 | Putative pilus assembly protein CpaE; Identified by similarity to GB:AAF40194.1. (405 aa) |
| | HNE_1145 | Iron compound ABC transporter, ATP-binding protein; Identified by similarity to SP:P15031; match to protein family HMM PF00005. (249 aa) |
| | HNE_1136 | Putative UDP-N-acetylmuramate--L-alanine ligase; Identified by match to protein family HMM PF01225; match to protein family HMM PF02875. (469 aa) |
| | HNE_1128 | Conserved hypothetical protein; Identified by similarity to GB:AAK24136.1. (295 aa) |
| | panC | Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (293 aa) |
| | rhlE | ATP-dependent RNA helicase RhlE; Identified by similarity to SP:P25888; match to protein family HMM PF00270; match to protein family HMM PF00271. (464 aa) |
| | gattA | glutamyl-tRNA (Gln) amidotransferase, A subunit; Identified by match to protein family HMM PF01425. (428 aa) |
| | HNE_1058 | Carbamoyl-phosphate synthase L chain/biotin carboxylase; Identified by match to protein family HMM PF00289; match to protein family HMM PF00364; match to protein family HMM PF02785; match to protein family HMM PF02786. (668 aa) |
| | clpA | ATP-dependent Clp protease, ATP-binding subunit ClpA; Identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM TIGR02639; Belongs to the ClpA/ClpB family. (771 aa) |
| | lon | ATP-dependent protease La; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (806 aa) |
| | parE | DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (665 aa) |
| | HNE_0950 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (527 aa) |
| | thrB | Homoserine kinase; Identified by similarity to SP:P29364; match to protein family HMM PF01636; match to protein family HMM TIGR00938; Belongs to the pseudomonas-type ThrB family. (328 aa) |
| | motR | motR protein; Identified by similarity to GB:AAC62540.2; match to protein family HMM PF01656. (278 aa) |
| | purD | Phosphoribosylamine--glycine ligase; Identified by match to protein family HMM PF01071; match to protein family HMM PF02842; match to protein family HMM PF02843; match to protein family HMM PF02844; match to protein family HMM TIGR00877; Belongs to the GARS family. (430 aa) |
| | mutL | Putative DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (634 aa) |
| | parC | DNA topoisomerase IV, A subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (744 aa) |
| | fcs2 | feruloyl-CoA synthetase; Identified by similarity to GB:CAB60226.1; match to protein family HMM PF00501. (622 aa) |
| | ileS | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). (1013 aa) |
| | ribF | Riboflavin biosynthesis protein RibF; Identified by match to protein family HMM PF01687; match to protein family HMM PF06574; match to protein family HMM TIGR00083; Belongs to the ribF family. (308 aa) |
| | alkK | medium-chain-fatty-acid-CoA ligase; Identified by similarity to SP:Q00594; match to protein family HMM PF00501. (541 aa) |
| | HNE_0796 | Lipopolysaccharide ABC transporter, ATP-binding protein; Identified by similarity to GB:AAF04381.1; match to protein family HMM PF00005. (417 aa) |
| | metK | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (393 aa) |
| | cysD | Sulfate adenylyltransferase, small subunit; Identified by match to protein family HMM PF01507; match to protein family HMM TIGR02039. (328 aa) |
| | cysNC | Sulfate adenylyltransferase, large subunit/adenylylsulfate kinase; Catalyzes the synthesis of activated sulfate. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (643 aa) |
| | dnaJ | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (386 aa) |
| | HNE_0754 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (608 aa) |
| | HNE_0741 | DnaA domain protein; Identified by similarity to GB:AAK23042.1. (114 aa) |
| | HNE_0723 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (254 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (460 aa) |
| | HNE_0708 | Nucleotide binding protein; Identified by match to protein family HMM PF01656. (435 aa) |
| | lpxK | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (332 aa) |
| | HNE_0695 | Putative ATP-dependent RNA helicase RhlE; Identified by similarity to SP:P25888; match to protein family HMM PF00270; match to protein family HMM PF00271; Belongs to the DEAD box helicase family. (536 aa) |
| | ppdK | Pyruvate, phosphate dikinase; Identified by similarity to SP:P22983; match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family. (905 aa) |
| | glyS | glycyl-tRNA synthetase, beta subunit; Identified by match to protein family HMM PF02092; match to protein family HMM PF05746; match to protein family HMM TIGR00211. (706 aa) |
| | glyQ | glycyl-tRNA synthetase, alpha subunit; Identified by match to protein family HMM PF02091; match to protein family HMM TIGR00388. (295 aa) |
| | ispE | 4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (298 aa) |
| | HNE_0666 | Putative localization factor protein PodJ; Identified by similarity to SP:Q9ZG88; match to protein family HMM PF01471. (1238 aa) |
| | carB | Carbamoyl-phosphate synthase, large subunit; Identified by match to protein family HMM PF00289; match to protein family HMM PF02142; match to protein family HMM PF02786; match to protein family HMM PF02787; match to protein family HMM TIGR01369; Belongs to the CarB family. (1092 aa) |
| | trmU | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (394 aa) |
| | clpB | ATP-dependent chaperone protein ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (872 aa) |
| | HNE_0618 | Asparate kinase, monofunctional class; Identified by similarity to SP:P41403; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657; Belongs to the aspartokinase family. (415 aa) |
| | HNE_0604 | ATP-dependent helicase, DEAD/DEAH family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271. (875 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (236 aa) |
| | hisS | histidyl-tRNA synthetase; Identified by match to protein family HMM PF00587; match to protein family HMM PF03129; match to protein family HMM TIGR00442. (497 aa) |
| | HNE_0567 | Identified by match to protein family HMM PF03109. (454 aa) |
| | dnaA | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. (457 aa) |
| | recF | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (370 aa) |
| | HNE_0553 | ATP-dependent RNA helicase, DEAD/DEAH box family; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF03880; Belongs to the DEAD box helicase family. (708 aa) |
| | gyrB | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (814 aa) |
| | recQ | ATP-dependent DNA helicase RecQ; Identified by similarity to GB:AAA24517.1; match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF00570; match to protein family HMM TIGR00614; match to protein family HMM TIGR01389. (615 aa) |
| | exsB | exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (239 aa) |
| | HNE_0525 | Heat shock protein, Hsp70 family; Identified by similarity to SP:P36928. (437 aa) |
| | trpS | tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (344 aa) |
| | HNE_0498 | Conserved hypothetical protein; Identified by similarity to GB:AAK23436.1; match to protein family HMM PF00004; match to protein family HMM PF07728. (294 aa) |
| | HNE_0468 | Conserved hypothetical protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family. (410 aa) |
| | miaA | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (316 aa) |
| | pheT | phenylalanyl-tRNA synthetase, beta subunit; Identified by similarity to SP:P07395; match to protein family HMM PF01588; match to protein family HMM PF03147; match to protein family HMM PF03483; match to protein family HMM PF03484; match to protein family HMM TIGR00472; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (797 aa) |
| | pheS | phenylalanyl-tRNA synthetase, alpha subunit; Identified by match to protein family HMM PF01409; match to protein family HMM PF02912; match to protein family HMM TIGR00468; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (358 aa) |
| | argB | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (297 aa) |
| | HNE_0407 | Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518. (474 aa) |
| | hrpB | ATP-dependent helicase HrpB; Identified by match to protein family HMM PF00270; match to protein family HMM PF00271; match to protein family HMM PF04408; match to protein family HMM TIGR01970. (812 aa) |
| | ddl | D-alanine--D-alanine ligase; Cell wall formation. (306 aa) |
| | ftsA | Cell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (431 aa) |
| | HNE_0385 | Putative DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (594 aa) |
| | dnaX | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (578 aa) |
| | prs | Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | HNE_0342 | ATPase, AAA family; Identified by match to protein family HMM PF07726. (332 aa) |
| | HNE_0331 | ATPase, AFG1 family; Identified by match to protein family HMM PF03969. (380 aa) |
| | HNE_0320 | Hypothetical protein; Identified by Glimmer2; putative. (664 aa) |
| | sucC | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa) |
| | gshB | Glutathione synthase; Identified by match to protein family HMM PF02951; match to protein family HMM PF02955; match to protein family HMM TIGR01380; Belongs to the prokaryotic GSH synthase family. (316 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (890 aa) |
| | HNE_0287 | Conserved hypothetical protein; Identified by similarity to GB:CAI07457.1. (456 aa) |
| | HNE_0284 | Conserved domain protein; Identified by similarity to SP:P55386. (793 aa) |
| | fliI | Flagellar protein export ATPase FliI; Identified by match to protein family HMM PF00006; match to protein family HMM TIGR01026; match to protein family HMM TIGR02545. (462 aa) |
| | HNE_0236 | Hypothetical protein; Identified by Glimmer2; putative. (521 aa) |
| | HNE_0229 | Response regulator; Identified by match to protein family HMM PF00072. (119 aa) |
| | rbsK | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (280 aa) |
| | HNE_0205 | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAK25562.1; match to protein family HMM PF00005. (244 aa) |
| | cmk | Cytidylate kinase; Identified by match to protein family HMM PF02224; match to protein family HMM TIGR00017. (212 aa) |
| | HNE_0186 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (231 aa) |
| | HNE_0172 | Peptide ABC transporter, ATP-binding protein; Identified by similarity to SP:P75796; match to protein family HMM PF00005; match to protein family HMM TIGR01727; Belongs to the ABC transporter superfamily. (623 aa) |
| | fcs1 | feruloyl-CoA synthetase; Identified by similarity to GB:CAB60226.1; match to protein family HMM PF00501. (617 aa) |
| | HNE_0163 | Conserved hypothetical protein; Identified by similarity to SP:P73436; match to protein family HMM PF02696. (475 aa) |
| | ftsH | ATP-dependent metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (639 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (367 aa) |
| | ruvB | Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (344 aa) |
| | ruvA | Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (207 aa) |
| | HNE_0104 | Identified by match to protein family HMM PF02562. (314 aa) |
| | baiB | Bile acid-coenzyme A ligase; Identified by similarity to SP:P19409; match to protein family HMM PF00501. (485 aa) |
| | HNE_0085 | DnaJ domain protein; Identified by match to protein family HMM PF00226. (207 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa) |
| | hisE | phosphoribosyl-ATP diphosphatase; Identified by similarity to SP:P50935; match to protein family HMM PF01503; Belongs to the PRA-PH family. (120 aa) |
| | coaE | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa) |
| | HNE_0001 | Conserved hypothetical protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation. (280 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (418 aa) |
| | parA | Chromosome partitioning protein ParA; Identified by similarity to SP:O05189; match to protein family HMM PF01656. (268 aa) |
| | leuS | leucyl-tRNA synthetase; Identified by match to protein family HMM PF00133; match to protein family HMM TIGR00396; Belongs to the class-I aminoacyl-tRNA synthetase family. (855 aa) |
| | HNE_3541 | Identified by match to protein family HMM PF01580. (837 aa) |
| | ccmA | Heme exporter protein CcmA; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. CcmA exporter (TC 3.A.1.107) family. (193 aa) |
| | HNE_3509 | ABC transporter, ATP-binding protein; Identified by match to protein family HMM PF00005. (243 aa) |
| | purK | Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (359 aa) |
| | cobS | Cobaltochelatase, CobS subunit; Identified by similarity to SP:P29933; match to protein family HMM TIGR01650. (327 aa) |
| | argG | Argininosuccinate synthase; Identified by match to protein family HMM PF00764; match to protein family HMM TIGR00032; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (413 aa) |
| | HNE_3481 | Identified by match to protein family HMM PF00749; Belongs to the class-I aminoacyl-tRNA synthetase family. (281 aa) |
| | accD | acetyl-CoA carboxylase, carboxyl transferase, beta subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA. (326 aa) |
| | HNE_3472 | Putative folylpolyglutamate synthase; Identified by match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family. (417 aa) |
| | HNE_3460 | Putative ATP:cob(I)alamin adenosyltransferase; Identified by match to protein family HMM PF01923; match to protein family HMM TIGR00636; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa) |
| | HNE_3440 | Putative uridine kinase; Identified by similarity to SP:O32033; match to protein family HMM PF00485; match to protein family HMM TIGR00235; Belongs to the uridine kinase family. (228 aa) |
| | nadD | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (195 aa) |
| | fcs5 | feruloyl-CoA synthetase; Identified by similarity to GB:CAC18323.1; match to protein family HMM PF00501. (522 aa) |
| | HNE_3391 | Putative permease; Identified by match to protein family HMM PF02687. (290 aa) |
| | ftsE | Cell division ATP-binding protein FtsE; Identified by similarity to GB:AAK20881.1; match to protein family HMM PF00005; match to protein family HMM TIGR02673. (252 aa) |
| | dnaK | Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (631 aa) |
| | grpE | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] (188 aa) |
| | fhs | Formate--tetrahydrofolate ligase; Identified by match to protein family HMM PF01268; Belongs to the formate--tetrahydrofolate ligase family. (556 aa) |
| | pspF | Psp operon transcription activator; Identified by similarity to SP:P37344; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (368 aa) |
| | ubiB | 2-polyprenylphenol 6-hydroxylase; Identified by match to protein family HMM PF03109; match to protein family HMM TIGR01982. (507 aa) |
| | HNE_3241 | Putative multidrug ABC transporter, permease/ATP-binding protein; Identified by similarity to GB:BAB70471.1; match to protein family HMM PF00005. (622 aa) |
| | cysS | cysteinyl-tRNA synthetase; Identified by match to protein family HMM PF01406; match to protein family HMM TIGR00435; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). (657 aa) |
| | HNE_3192 | Efflux ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. (610 aa) |
| | pgk | Phosphoglycerate kinase; Identified by similarity to SP:P40924; match to protein family HMM PF00162; Belongs to the phosphoglycerate kinase family. (398 aa) |
| | secA | Preprotein translocase, SecA subunit; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. Belongs to the SecA family. (921 aa) |
| | HNE_3165 | ABC transporter, ATP-binding protein; Identified by similarity to GB:AAC36155.1; match to protein family HMM PF00005. (323 aa) |
| | tdk | Thymidine kinase; Identified by similarity to SP:P23331; match to protein family HMM PF00265. (195 aa) |
| | HNE_3139 | tRNA synthetase, class II; Identified by match to protein family HMM PF00152. (347 aa) |
| | HNE_3120 | Conserved hypothetical protein; Identified by similarity to GB:AAP09809.1. (174 aa) |
| | HNE_3114 | alpha-L-glutamate ligases, RimK family; Identified by match to protein family HMM TIGR00768; Belongs to the RimK family. (304 aa) |
| | HNE_3089 | ABC transporter, permease/ATP-binding protein; Identified by similarity to SP:P33116; match to protein family HMM PF00005. (622 aa) |
| | lysS | lysyl-tRNA synthetase; Identified by match to protein family HMM PF01921; match to protein family HMM TIGR00467; Belongs to the class-I aminoacyl-tRNA synthetase family. (530 aa) |
| | uvrB | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (681 aa) |
| | HNE_3039 | Sigma-54 dependent DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00158; match to protein family HMM PF02954; match to protein family HMM TIGR01199. (491 aa) |
| | murE | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diamino-pimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (478 aa) |
| | murF | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (478 aa) |
| | murD | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (471 aa) |
| | murC | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. (474 aa) |
| | HNE_3012 | Pilus assembly protein CpaE; Identified by similarity to GB:AAF40194.1. (468 aa) |
| | cpaF | Pilus assembly protein CpaF; Identified by similarity to GB:AAF40195.1; match to protein family HMM PF00437. (495 aa) |
| | HNE_2938 | Putative DNA helicase II; Identified by similarity to SP:P03018; match to protein family HMM PF00580. (781 aa) |
