STRINGSTRING
metK metK ahcY ahcY metF metF metZ metZ metE metE thrB thrB metH metH metY metY NE2369 NE2369 thrC thrC PatB PatB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metKS-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (387 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (478 aa)
metFmetF; 5,10-methylenetetrahydrofolate reductase oxidoreductase protein; Belongs to the methylenetetrahydrofolate reductase family. (281 aa)
metZCys/Met metabolism pyridoxal-phosphate-dependent enzymes; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (391 aa)
metEMethionine synthase, vitamin-B12 independent; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (758 aa)
thrBPutative homoserine kinase protein; Belongs to the pseudomonas-type ThrB family. (316 aa)
metHmetH Methionine synthase I, cobalamin-binding domain; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1237 aa)
metYCys/Met metabolism pyridoxal-phosphate-dependent enzymes. (422 aa)
NE2369Homoserine dehydrogenase:ACT domain. (438 aa)
thrCthrC; probable threonine synthase protein. (468 aa)
PatBAminotransferases class-I. (393 aa)
Your Current Organism:
Nitrosomonas europaea
NCBI taxonomy Id: 228410
Other names: N. europaea ATCC 19718, Nitrosomonas europaea ATCC 19718, Nitrosomonas europaea str. ATCC 19718
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.