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yvgR yvgR cysH cysH trxA trxA dsbB dsbB NE1319 NE1319 dsbC dsbC NE0774 NE0774 yfgD yfgD msrA msrA NE1911 NE1911 dsbA dsbA trxB trxB NE2157 NE2157 grxC grxC lpdA3 lpdA3 dsbD dsbD NE2390 NE2390 NE2465 NE2465 merA merA yvgQ yvgQ ccmG ccmG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
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Your Input:
yvgRSulfite reductase flavoprotein subunit; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (611 aa)
cysHProbable cysH; Reduction of activated sulfate into sulfite. (232 aa)
trxAThioredoxin; Belongs to the thioredoxin family. (108 aa)
dsbBDisulfide bond formation protein DsbB; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (164 aa)
NE1319Thioredoxin. (153 aa)
dsbCHypothetical protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (237 aa)
NE0774Pyridine nucleotide-disulfide oxidoreductase, class I; Product taken from KEGG top hit (ev=e-98). (472 aa)
yfgDSignal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.958) with cleavage site probability 0.754 at residue 26; Belongs to the ArsC family. (115 aa)
msrAPossible msrA, pms; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (445 aa)
NE1911Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (102 aa)
dsbAThioredoxin:DSBA oxidoreductase. (216 aa)
trxBFAD-dependent pyridine nucleotide-disulphide oxidoreductase. (317 aa)
NE2157Dihydrolipoamide dehydrogenase. (600 aa)
grxCGlutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (85 aa)
lpdA3pdA3; dihydrolipoamide dehydrogenase E3 component. (490 aa)
dsbDThioredoxin:Cytochrome c biogenesis protein transmembrane region; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (646 aa)
NE2390Thioredoxin. (182 aa)
NE2465Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
merAmerA; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (561 aa)
yvgQNitrite and sulfite reductase; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (573 aa)
ccmGPeriplasmic protein thiol:disulfide oxidoreductase DsbE. (174 aa)
Your Current Organism:
Nitrosomonas europaea
NCBI taxonomy Id: 228410
Other names: N. europaea ATCC 19718, Nitrosomonas europaea ATCC 19718, Nitrosomonas europaea str. ATCC 19718
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