STRINGSTRING
bacA bacA motB motB ispZ ispZ NE0063 NE0063 NE0070 NE0070 NE0071 NE0071 NE0081 NE0081 NE0097 NE0097 lgt lgt NE0106 NE0106 NE0127 NE0127 NE0130 NE0130 NE0147 NE0147 NE0151 NE0151 mexE mexE acrA,mtcA,lir acrA,mtcA,lir TRm2011-2C TRm2011-2C NE0294 NE0294 NE0345 NE0345 NE0346 NE0346 NE0374 NE0374 NE0375 NE0375 NE0388 NE0388 NE0524 NE0524 NE0525 NE0525 NE0534 NE0534 yegM yegM NE0542 NE0542 NE0548 NE0548 NE0555 NE0555 NE0558 NE0558 cysA cysA cysW cysW NE0636 NE0636 NE0669 NE0669 NE0670 NE0670 NE0801 NE0801 NE0802 NE0802 NE0817 NE0817 NE0825 NE0825 NE0826 NE0826 NE0828 NE0828 merT merT pntAa pntAa pntAb2 pntAb2 pntB pntB NE0979 NE0979 ftsI ftsI mraY mraY ctaG ctaG NE1025 NE1025 NE1031 NE1031 ftsK ftsK NE1070 NE1070 NE1078 NE1078 macB macB NE1082 NE1082 NE1085 NE1085 NE1095 NE1095 NE1098 NE1098 NE1102 NE1102 NE1113 NE1113 NE1120 NE1120 NE1130 NE1130 yajC yajC lspA lspA NE1157 NE1157 lnt lnt NE1191 NE1191 NE1210 NE1210 NE1211 NE1211 fecR fecR NE1283 NE1283 NE1284 NE1284 NE1296 NE1296 NE1328 NE1328 rkpT1 rkpT1 NE1387 NE1387 ftsE ftsE NE1634 NE1634 czcA czcA czcB czcB coq7 coq7 crcB crcB NE1736 NE1736 NE1802 NE1802 wza wza trkA trkA NE1835 NE1835 argH argH potA potA potB potB NE1898 NE1898 NE1900 NE1900 NE1989 NE1989 NE2139 NE2139 NE2183 NE2183 NE2243 NE2243 yccZ yccZ mrcA mrcA NE2382 NE2382 NE2383 NE2383 NE2386 NE2386 mviN mviN cstA cstA NE2434 NE2434 mdoH mdoH NE2485 NE2485 NE2548 NE2548 NE2550 NE2550 pgpA pgpA NE2563 NE2563
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
bacABacitracin resistance protein BacA; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family. (273 aa)
motBBacterial outer membrane protein. (307 aa)
ispZHypothetical protein; Involved in cell division; probably involved in intracellular septation; Belongs to the YciB family. (181 aa)
NE0063ATPase component ABC-type (unclassified) transport system. (240 aa)
NE00707, 8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase. (170 aa)
NE0071Deoxynucleoside kinase. (214 aa)
NE0081Possible transmembrane protein. (240 aa)
NE0097Haloacid dehalogenase/epoxide hydrolase family. (221 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (278 aa)
NE0106Possible ABC transport permease; Domain of unknown function DUF140. (386 aa)
NE0127Possible tonB-dependent receptor protein; Pseudogene; it contains at least 2 frameshifts; the parts of the original gene are NE0126, NE0125 and NE0124. (349 aa)
NE0130Conserved hypothetical protein. (90 aa)
NE0147Conserved hypothetical protein; COGs COG1426. (354 aa)
NE0151Conserved hypothetical protein; InterPro IPR001687 COGs COG2976. (214 aa)
mexEHlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (388 aa)
acrA,mtcA,lirHlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (399 aa)
TRm2011-2CConserved hypothetical protein; 2 probable transmembrane helices predicted by TMHMM2.0. (506 aa)
NE0294Cytochrome c, class I. (647 aa)
NE0345Acriflavin resistance protein:Heavy metal efflux pump CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1042 aa)
NE0346Possible cation transporter transmembrane protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (393 aa)
NE0374Putative cation efflux protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (387 aa)
NE0375Acriflavin resistance protein:Heavy metal efflux pump CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1034 aa)
NE0388Domain of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family. (69 aa)
NE0524CBS domain. (127 aa)
NE0525CBS domain. (136 aa)
NE0534Putative transmembrane sensor. (308 aa)
yegMPossible putitive HlyD family secretion protein. (397 aa)
NE0542Possible transmembrane sensor. (327 aa)
NE0548Putative transmembrane sensor. (316 aa)
NE0555Possible transmembrane sensor. (309 aa)
NE0558Putative transcriptional regulator, putative. (343 aa)
cysAcysA; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (362 aa)
cysWcysW; sulfate transport ABC transporter protein. (292 aa)
NE0636TonB-dependent receptor protein. (612 aa)
NE0669Acriflavin resistance protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1046 aa)
NE0670Possible membrane fusion protein MtrC. (332 aa)
NE0801Conserved hypothetical protein; COGs COG0795. (358 aa)
NE0802Putative membrane protein. (355 aa)
NE0817Putative transmembrane sensor. (334 aa)
NE0825DUF214. (399 aa)
NE0826DUF214. (400 aa)
NE0828HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (384 aa)
merTMerT mercuric transport protein. (116 aa)
pntAaAlanine dehydrogenase and pyridine nucleotide transhydrogenase. (375 aa)
pntAb2Similar to (NC_003296) PROBABLE TRANSMEMBRANE NAD(P) TRANSHYDROGENASE (ALPHA SUBUNIT PART 2) TRANSMEMBRANE PROTEIN [Ralstonia solanacearum] evalue=6.00e-34, 69% identity. (102 aa)
pntBNAD(P) transhydrogenase beta subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (459 aa)
NE0979Putative transmembrane sensor. (347 aa)
ftsIPenicillin binding protein transpeptidase domain; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (580 aa)
mraYmraY; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa)
ctaGPutative cytochrome C oxidase assembly transmembrane protein. (174 aa)
NE1025Bacterial outer membrane protein. (220 aa)
NE1031Putative iron transport system ATP-binding protein; Belongs to the ABC transporter superfamily. (356 aa)
ftsKFtsK/SpoIIIE family:AAA ATPase superfamily. (767 aa)
NE1070Helix-turn-helix motif; Pseudogene, contains 2 premature stop codons, the other part of the gene is NE1068. (322 aa)
NE1078Putative transmembrane sensor. (347 aa)
macBProbable ATP-binding/permease fusion ABC transporter; Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP- binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. (659 aa)
NE1082Conserved hypothetical protein; COGs COG0845; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (398 aa)
NE1085Putative transmembrane sensor. (337 aa)
NE1095Possible TonB-dependent receptor; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.980) with cleavage site probability 0.732 at residue 24. (343 aa)
NE1098Putative transmembrane sensor. (328 aa)
NE1102Putative transmembrane sensor. (352 aa)
NE1113HlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (386 aa)
NE1120Putative orf; Unknown function. (55 aa)
NE1130Hypothetical protein. (411 aa)
yajCDomain of unknown function DUF219; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. (158 aa)
lspASignal peptidase II/lipoprotein signal peptidase family (A8); This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (160 aa)
NE1157Hypothetical protein. (297 aa)
lntCarbon-nitrogen hydrolase:Apolipoprotein N-acyltransferase; Catalyzes the phospholipid dependent N-acylation of the N- terminal cysteine of apolipoprotein, the last step in lipoprotein maturation; Belongs to the CN hydrolase family. Apolipoprotein N- acyltransferase subfamily. (497 aa)
NE1191Putative transmembrane sensor. (408 aa)
NE1210Putative ABC transporter permease protein. (383 aa)
NE1211Putative ABC transporter permease protein. (374 aa)
fecRPutative FecR protein. (321 aa)
NE1283Conserved hypothetical protein; COGs COG3242. (66 aa)
NE1284Band 7 protein; HflC and HflK could regulate a protease. (292 aa)
NE1296Cyclic nucleotide-binding domain:cAMP-dependent protein kinase. (249 aa)
NE1328Possible transmembrane protein. (1290 aa)
rkpT1ABC 2 transport system integral membrane protein. (261 aa)
NE1387Polysaccharide export protein. (396 aa)
ftsEUncharacterized ABC-type transport system ATPase component/cell division protein. (220 aa)
NE1634Hypothetical protein. (370 aa)
czcAAcriflavin resistance protein:Heavy metal efflux pump CzcA; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family. (1072 aa)
czcBHlyD family secretion protein; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (497 aa)
coq7Conserved hypothetical protein; Catalyzes the hydroxylation of 2-nonaprenyl-3-methyl-6- methoxy-1,4-benzoquinol during ubiquinone biosynthesis. (208 aa)
crcBCRCB protein; Important for reducing fluoride concentration in the cell, thus reducing its toxicity; Belongs to the CrcB (TC 9.B.71) family. (127 aa)
NE1736Putative transport system permease. (278 aa)
NE1802Hypothetical protein. (524 aa)
wzaPutative polysaccharide export protein, outer membrane. (205 aa)
trkAPotassium uptake system NAD-binding component. (481 aa)
NE1835Cation transport protein; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family. (489 aa)
argHargH: argininosuccinate lyase. (461 aa)
potApotA; Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family. (361 aa)
potBpotB; putative spermidine/putrescine transport system permease protein. (302 aa)
NE1898Conserved hypothetical protein; COGs COG0845; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (381 aa)
NE1900DUF214. (407 aa)
NE1989Putative tonB-dependent receptor protein; NE1987 and NE1988 are 2 parts of a dead gene due to a frameshift. (336 aa)
NE2139Putative transmembrane sensor. (320 aa)
NE2183Conserved hypothetical protein; InterPro IPR004701 COGs COG2893. (134 aa)
NE2243Hypothetical protein. (476 aa)
yccZPolysaccharide export protein. (405 aa)
mrcAmrcA; penicillin-binding 1 (peptidoglycan synthetase) transmembrane protein. (770 aa)
NE2382Mce related protein. (159 aa)
NE2383Domain of unknown function DUF140. (271 aa)
NE2386Bacterial SH3 domain homologue. (228 aa)
mviNVirulence factor MVIN-like; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (509 aa)
cstACarbon starvation protein CstA. (690 aa)
NE2434Putative transmembrane sensor. (338 aa)
mdoHGlycosyl transferase, family 2; Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs). (867 aa)
NE2485Possible TonB-dependent receptor; Signal predicted by SignalP 2.0 HMM (Signal peptide probabilty 0.847) with cleavage site probability 0.655 at residue 52. (350 aa)
NE2548Bacterial outer membrane protein. (231 aa)
NE2550Putative ABC-2 type transport system permease protein. (248 aa)
pgpAProbable phosphatidyl-glycerophosphatase hydrolase transmembrane protein; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (180 aa)
NE2563General diffusion Gram-negative porins. (404 aa)
Your Current Organism:
Nitrosomonas europaea
NCBI taxonomy Id: 228410
Other names: N. europaea ATCC 19718, Nitrosomonas europaea ATCC 19718, Nitrosomonas europaea str. ATCC 19718
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