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ilvD ilvD leuC leuC leuD leuD leuB leuB asd asd argA argA aatA aatA acnA1 acnA1 argB argB leuA1 leuA1 ilvC ilvC ilvH ilvH ilvI ilvI argD argD argC argC icd icd ilvE ilvE lysC lysC argJ argJ NE2368 NE2368 gltA gltA
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ilvDDihydroxyacid dehydratase/phosphogluconate dehydratase; Belongs to the IlvD/Edd family. (557 aa)
leuCleuC; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (470 aa)
leuDleuD; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (221 aa)
leuBleuB, 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. (356 aa)
asdSemialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (373 aa)
argAGCN5-related N-acetyltransferase:Aspartokinase superfamily; Belongs to the acetyltransferase family. ArgA subfamily. (444 aa)
aatAAminotransferases class-I; Catalyzes the reversible conversion of aspartate and 2- oxoglutarate to glutamate and oxaloacetate. Can also transaminate prephenate in the presence of glutamate, with lower efficiency. (397 aa)
acnA1acnA1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (948 aa)
argBAspartokinase superfamily:Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (295 aa)
leuA1HMG-CoA Lyase-like family; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (510 aa)
ilvCProbable ketol-acid reductoisomerase oxidoreductase protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (338 aa)
ilvHSimilar to (NC_003295) PROBABLE ACETOLACTATE SYNTHASE ISOZYME III (SMALL SUBUNIT) PROTEIN [Ralstonia solanacearum] evalue=3.00e-61, 71% identity. (163 aa)
ilvIThiamine pyrophosphate dependent enzyme. (567 aa)
argDargD; acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (393 aa)
argCargC; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa)
icdIcd; isocitrate dehydrogenase [NADP] oxidoreductase protein. (415 aa)
ilvEAminotransferases class-IV; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (307 aa)
lysCAspartokinase superfamily:ACT domain; Belongs to the aspartokinase family. (415 aa)
argJArgJ family; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
NE2368Aspartate aminotransferase. (408 aa)
gltACitrate synthase; Belongs to the citrate synthase family. (427 aa)
Your Current Organism:
Nitrosomonas europaea
NCBI taxonomy Id: 228410
Other names: N. europaea ATCC 19718, Nitrosomonas europaea ATCC 19718, Nitrosomonas europaea str. ATCC 19718
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