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rpl37ae rpl37ae rps12 rps12 rpl23 rpl23 rpl18 rpl18 tuf tuf rps10 rps10 rpl10 rpl10 rpl14 rpl14 rpl5 rpl5 rpl11 rpl11 rpl4 rpl4 NEQ178 NEQ178 NEQ179 NEQ179 NEQ180 NEQ180 rpl15e rpl15e rpl44e rpl44e rps19e rps19e rpl12 rpl12 rpl22 rpl22 rpl13 rpl13 proS proS ef1b ef1b rpl6 rpl6 rps7 rps7 rps4 rps4 rpl24 rpl24 rps8 rps8 rpl34e rpl34e rpl35ae rpl35ae rpl30 rpl30 rpl15 rpl15 rps17e rps17e rpl18a rpl18a rpl2 rpl2 NEQ364 NEQ364 rps3ae rps3ae rpl19e rpl19e rps5 rps5 rpl21e rpl21e map map rpl3 rpl3 NEQ446 NEQ446 rpl10e rpl10e NEQ452 NEQ452 rps13 rps13 rps8e rps8e rps4e rps4e rps19 rps19 rps15 rps15 rpl18e rpl18e infB infB rps2 rps2 eif6 eif6 rpl32e rpl32e fusA fusA rpl1 rpl1 rps24e rps24e
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rpl37aeNEQ038; Binds to the 23S rRNA. (86 aa)
rps12NEQ058; With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits. Belongs to the universal ribosomal protein uS12 family. (143 aa)
rpl23NEQ065; Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Belongs to the universal ribosomal protein uL23 family. (78 aa)
rpl18NEQ075; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. (195 aa)
tufNEQ082; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (433 aa)
rps10NEQ083; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (109 aa)
rpl10NEQ091; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (284 aa)
rpl14NEQ092; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (133 aa)
rpl5NEQ093; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. May contact the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (169 aa)
rpl11NEQ101; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family. (160 aa)
rpl4NEQ146; One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (268 aa)
NEQ178NEQ178; LSU ribosomal protein L14E [Methanococcus jannaschii]; COG2163: Ribosomal protein L14E; IPR002784: Ribosomal protein L14. (114 aa)
NEQ179NEQ179; Ribosomal protein L7Ae/L30E/S12e/Gadd45 family [Methanococcus jannaschii]; COG1911: Ribosomal protein L30E; IPR000955: Ribosomal protein L7AE; IPR000231: Ribosomal protein L30e. (86 aa)
NEQ180NEQ180; Putative transcription factor [Methanococcus vannielii]; COG0195: Transcription terminator. (136 aa)
rpl15eNEQ181; LSU ribosomal protein L15E; [Pyrococcus furiosus]; COG1632: Ribosomal protein L15E; IPR000439: Ribosomal protein L15e; IPR001687: ATP/GTP-binding site motif A (P-loop); IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL15 family. (190 aa)
rpl44eNEQ183; Binds to the 23S rRNA. (108 aa)
rps19eNEQ187; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family. (162 aa)
rpl12NEQ201; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family. (102 aa)
rpl22NEQ204; This protein binds specifically to 23S rRNA. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome. (174 aa)
rpl13NEQ207; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (162 aa)
proSNEQ210; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (537 aa)
ef1bNEQ220; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA. (81 aa)
rpl6NEQ241; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (192 aa)
rps7NEQ242; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center; Belongs to the universal ribosomal protein uS7 family. (198 aa)
rps4NEQ247; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. (180 aa)
rpl24NEQ257; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. (140 aa)
rps8NEQ274; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (129 aa)
rpl34eNEQ297; LSU ribosomal protein L34E [Methanococcus jannaschii]; COG2174: Ribosomal protein L34E; IPR001284: Ribosomal protein L34e; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL34 family. (83 aa)
rpl35aeNEQ303; LSU ribosomal protein L35AE [Pyrococcus abyssi]; COG2451: Ribosomal protein L35AE/L33A; IPR001780: Ribosomal protein L35Ae; Belongs to the eukaryotic ribosomal protein eL33 family. (85 aa)
rpl30NEQ311; LSU ribosomal protein L30P [Methanococcus jannaschii]; COG1841: Ribosomal protein L30/L7E; IPR000517: Ribosomal protein L30. (155 aa)
rpl15NEQ317; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. (138 aa)
rps17eNEQ320; SSU ribosomal protein S17E [Pyrococcus horikoshii]; COG1383: Ribosomal protein S17E; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eS17 family. (72 aa)
rpl18aNEQ346; LSU ribosomal protein LX [Pyrococcus horikowshii]; COG2157: Ribosomal protein L20A (L18A); IPR002768: Ribosomal LX protein. (78 aa)
rpl2NEQ361; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family. (238 aa)
NEQ364NEQ364; LSU ribosomal protein L31E [Methanococcus jannaschii]; COG2097: Ribosomal protein L31E; IPR000054: Ribosomal protein L31e. (79 aa)
rps3aeNEQ375; Ribosomal protein S3AE [Methanopyrus kandleri]; COG1890: Ribosomal protein S3AE; IPR001593: Ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family. (227 aa)
rpl19eNEQ379; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family. (147 aa)
rps5NEQ388; With S4 and S12 plays an important role in translational accuracy. (231 aa)
rpl21eNEQ397; LSU ribosomal protein L21E [Pyrococcus furiosus]; COG2139: Ribosomal protein L21E; IPR001147: Ribosomal protein L21E; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL21 family. (170 aa)
mapNEQ399; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val); Belongs to the peptidase M24A family. Methionine aminopeptidase archaeal type 2 subfamily. (284 aa)
rpl3NEQ433; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (321 aa)
NEQ446NEQ446; SSU ribosomal protein S9P [Pyrococcus furiosus]; COG0103: Ribosomal protein S9; IPR000754: Ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. (136 aa)
rpl10eNEQ450; L10e ribosomal protein [Archaeoglobus fulgidus]; COG0197: Ribosomal protein L16/L10E; IPR001197: Ribosomal protein L10E; Belongs to the universal ribosomal protein uL16 family. (186 aa)
NEQ452NEQ452; DNA-directed RNA polymerase, subunit D [Pyrococcus abyssi]; COG0202: DNA-directed RNA polymerase alpha subunit/40 kD subunit; IPR001514: RNA polymerases D/30 to 40 Kd subunits. (227 aa)
rps13NEQ467; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement; Belongs to the universal ribosomal protein uS13 family. (153 aa)
rps8eNEQ469; SSU ribosomal protein S8E [Archaeoglobus fulgidus]; COG2007: Ribosomal protein S8E; IPR001047: Ribosomal protein S8E; IPR001472: Bipartite nuclear localization signal. (127 aa)
rps4eNEQ478; Ribosomal protein S4 [Methanothermobacter thermautotrophicus]; COG1471: Ribosomal protein S4E; IPR000876: Ribosomal protein S4E; IPR002942: S4 domain. (234 aa)
rps19NEQ480; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (140 aa)
rps15NEQ487; Ribosomal protein S15P/S13E [Methanopyrus kandleri]; COG0184: Ribosomal protein S15P/S13E; IPR000589: Ribosomal protein S15. (154 aa)
rpl18eNEQ489; LSU ribosomal protein L18E [Sulfolobus solfataricus]; COG1727: Ribosomal protein L18E; IPR000531: TonB-dependent receptor protein; IPR001196: Ribosomal protein L15; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL18 family. (118 aa)
infBNEQ498; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. (574 aa)
rps2NEQ508; 30S ribosomal protein S2 [Pyrococcus abyssi]; COG0052: Ribosomal protein S2; IPR001865: Ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. (201 aa)
eif6NEQ517; Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex. (208 aa)
rpl32eNEQ530; LSU ribosomal protein L32E [Pyrococcus abyssi]; COG1717: Ribosomal protein L32E; IPR001515: Ribosomal protein L32e; IPR001472: Bipartite nuclear localization signal; Belongs to the eukaryotic ribosomal protein eL32 family. (135 aa)
fusANEQ543; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (743 aa)
rpl1NEQ546; Binds directly to 23S rRNA. Probably involved in E site tRNA release. (213 aa)
rps24eNEQ548; SSU ribosomal protein S24E [Methanococcus jannashii]; COG2004: Ribosomal protein S24E; IPR001976: Ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. (94 aa)
Your Current Organism:
Nanoarchaeum equitans
NCBI taxonomy Id: 228908
Other names: Microarchaeum sp. Kin4-M, N. equitans Kin4-M, Nanoarchaeum equitans Kin4-M, Nanoarchaeum equitans str. Kin4-M
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