STRINGSTRING
hisB hisB SEM33814.1 SEM33814.1 SEM19914.1 SEM19914.1 SEM19875.1 SEM19875.1 SEM17598.1 SEM17598.1 SEM15362.1 SEM15362.1 SEM13378.1 SEM13378.1 SEM07483.1 SEM07483.1 hisG hisG hisD hisD hisC hisC hisH hisH hisA hisA hisF hisF hisI hisI SEL78481.1 SEL78481.1 SEL48344.1 SEL48344.1 SEL66644.1 SEL66644.1 SEL56459.1 SEL56459.1 hutG hutG hutU hutU SEL56154.1 SEL56154.1 SEL56122.1 SEL56122.1 SEL54849.1 SEL54849.1 SEL19073.1 SEL19073.1 SEL36485.1 SEL36485.1 SEL35894.1 SEL35894.1 SEL21510.1 SEL21510.1 SEL20836.1 SEL20836.1 SEK74599.1 SEK74599.1 SEK93987.1 SEK93987.1 SEK72193.1 SEK72193.1 SEK77911.1 SEK77911.1 SEK77866.1 SEK77866.1 SEK76237.1 SEK76237.1 SEK21004.1 SEK21004.1 SEK40007.1 SEK40007.1 SEK39960.1 SEK39960.1 SEK37508.1 SEK37508.1 SEK37428.1 SEK37428.1 SEK37326.1 SEK37326.1 SEK20164.1 SEK20164.1 SEK33284.1 SEK33284.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisBImidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (380 aa)
SEM33814.1Transposase. (357 aa)
SEM19914.1Imidazolonepropionase. (984 aa)
SEM19875.1Imidazolonepropionase. (441 aa)
SEM17598.1Imidazolonepropionase. (445 aa)
SEM15362.1Protein involved in gliding motility GldJ. (555 aa)
SEM13378.1Hypothetical protein. (98 aa)
SEM07483.1Hypothetical protein. (98 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa)
hisCHistidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa)
hisHGlutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa)
hisA1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (242 aa)
hisFCyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa)
hisIphosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (207 aa)
SEL78481.1Histidinol-phosphate aminotransferase. (371 aa)
SEL48344.1Transposase. (322 aa)
SEL66644.1Hypothetical protein. (103 aa)
SEL56459.1Histidinol-phosphate aminotransferase. (396 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (318 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (666 aa)
SEL56154.1Imidazolonepropionase; Belongs to the metallo-dependent hydrolases superfamily. HutI family. (415 aa)
SEL56122.1Histidine ammonia-lyase. (524 aa)
SEL54849.1Imidazolonepropionase. (424 aa)
SEL19073.1TfoX N-terminal domain-containing protein. (79 aa)
SEL36485.1Monoamine oxidase. (355 aa)
SEL35894.1Amidohydrolase family protein. (529 aa)
SEL21510.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (324 aa)
SEL20836.1Hypothetical protein. (371 aa)
SEK74599.1Histidinol-phosphate aminotransferase. (368 aa)
SEK93987.1Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. (517 aa)
SEK72193.1Hypothetical protein. (52 aa)
SEK77911.1Arginase family enzyme; Belongs to the arginase family. (385 aa)
SEK77866.1Protein involved in gliding motility GldK. (454 aa)
SEK76237.1Transposase. (322 aa)
SEK21004.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (325 aa)
SEK40007.1Amidohydrolase family protein. (476 aa)
SEK39960.1Imidazolonepropionase. (414 aa)
SEK37508.1Transposase IS116/IS110/IS902 family protein. (197 aa)
SEK37428.1Hypothetical protein. (54 aa)
SEK37326.1Transposase IS116/IS110/IS902 family protein. (157 aa)
SEK20164.1Monoamine oxidase. (493 aa)
SEK33284.1Formylglycine-generating enzyme, required for sulfatase activity, contains SUMF1/FGE domain. (377 aa)
Your Current Organism:
Maribacter orientalis
NCBI taxonomy Id: 228957
Other names: Bacteroidetes bacterium KMM 3947, CCUG 48008, DSM 16471, KCTC 12967, KMM 3947, M. orientalis, Maribacter orientalis Nedashkovskaya et al. 2004
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