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| | SEK37508.1 | Transposase IS116/IS110/IS902 family protein. (197 aa) |
| | SEK23906.1 | Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family. (299 aa) |
| | SEK19276.1 | Threonine synthase. (431 aa) |
| | thrB | Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (308 aa) |
| | SEK19352.1 | Aspartate kinase. (813 aa) |
| | rpiA | Ribose-5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (225 aa) |
| | SEK32934.1 | Transketolase; Belongs to the transketolase family. (676 aa) |
| | tal | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (217 aa) |
| | SEK19923.1 | Tagatose 6-phosphate kinase. (306 aa) |
| | SEK37326.1 | Transposase IS116/IS110/IS902 family protein. (157 aa) |
| | SEK37428.1 | Hypothetical protein. (54 aa) |
| | SEK20532.1 | Tagatose 1,6-diphosphate aldolase GatY/KbaY. (272 aa) |
| | SEK44435.1 | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (630 aa) |
| | SEK45466.1 | Isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (738 aa) |
| | SEK45739.1 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (482 aa) |
| | dapF | Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (258 aa) |
| | SEK46500.1 | Putative acetyltransferase. (161 aa) |
| | dapA | 4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (296 aa) |
| | SEK48694.1 | Histidine phosphatase superfamily (branch 1). (180 aa) |
| | glyA | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa) |
| | SEK49953.1 | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. (372 aa) |
| | SEK50013.1 | 2-isopropylmalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (389 aa) |
| | aroC | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (354 aa) |
| | SEK22437.1 | Fructose-bisphosphate aldolase. (348 aa) |
| | gpmA | 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (229 aa) |
| | SEK76237.1 | Transposase. (322 aa) |
| | SEK81606.1 | Agmatinase; Belongs to the arginase family. (260 aa) |
| | SEK81700.1 | Hypothetical protein. (210 aa) |
| | SEK81745.1 | Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (395 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (324 aa) |
| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (264 aa) |
| | SEK81884.1 | Acetylornithine aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (375 aa) |
| | proA | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (398 aa) |
| | proB | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (255 aa) |
| | SEK82016.1 | N-succinyl-L-ornithine transcarbamylase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (310 aa) |
| | argB | N-acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (259 aa) |
| | SEK82153.1 | Acetylornithine deacetylase. (354 aa) |
| | argH | Argininosuccinate lyase. (425 aa) |
| | SEK85932.1 | Saccharopine dehydrogenase, NADP-dependent. (457 aa) |
| | SEK72450.1 | Phenylalanine-4-hydroxylase. (587 aa) |
| | SEK88706.1 | Threonine dehydratase. (315 aa) |
| | SEK73047.1 | Transferase hexapeptide (six repeat-containing protein). (148 aa) |
| | SEK92190.1 | Cystathionine gamma-lyase. (384 aa) |
| | SEK95667.1 | Pyruvate kinase; Belongs to the pyruvate kinase family. (480 aa) |
| | SEK98096.1 | Acetyltransferase (GNAT) family protein. (166 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (329 aa) |
| | SEK99750.1 | Dihydroxyacid dehydratase; Belongs to the IlvD/Edd family. (573 aa) |
| | SEL00434.1 | GMP synthase-Glutamine amidotransferase. (278 aa) |
| | SEL02726.1 | Ser/Thr protein kinase RdoA involved in Cpx stress response, MazF antagonist. (351 aa) |
| | SEK74599.1 | Histidinol-phosphate aminotransferase. (368 aa) |
| | proC-2 | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa) |
| | proB-2 | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (262 aa) |
| | proA-2 | Glutamate-5-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (398 aa) |
| | SEK75483.1 | Beta-lysine acetyltransferase. (280 aa) |
| | SEL20778.1 | Alanine dehydrogenase/PNT, N-terminal domain. (401 aa) |
| | SEL20836.1 | Hypothetical protein. (371 aa) |
| | SEL21775.1 | Threonine synthase-related protein. (353 aa) |
| | SEL22440.1 | Asparagine synthase (glutamine-hydrolysing). (557 aa) |
| | tpiA | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (249 aa) |
| | SEL26849.1 | 6-phosphofructokinase 2; Belongs to the carbohydrate kinase PfkB family. (321 aa) |
| | SEL27485.1 | 6-phosphofructokinase 2; Belongs to the carbohydrate kinase PfkB family. (314 aa) |
| | SEL29312.1 | Glutamine synthetase. (338 aa) |
| | SEL29351.1 | Glutamine synthetase. (728 aa) |
| | SEL30370.1 | Branched-chain amino acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (356 aa) |
| | lysA | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (412 aa) |
| | SEL33968.1 | 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (271 aa) |
| | SEL37428.1 | Aconitase. (757 aa) |
| | eno | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa) |
| | aroK | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (174 aa) |
| | SEL16935.1 | Citrate synthase; Belongs to the citrate synthase family. (428 aa) |
| | SEL19073.1 | TfoX N-terminal domain-containing protein. (79 aa) |
| | SEL56459.1 | Histidinol-phosphate aminotransferase. (396 aa) |
| | SEL57736.1 | 3-hexulose-6-phosphate synthase. (209 aa) |
| | SEL57774.1 | 3-hexulose-6-phosphate isomerase. (194 aa) |
| | SEL58528.1 | Ribose-phosphate pyrophosphokinase. (313 aa) |
| | rsmA | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (288 aa) |
| | SEL59223.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (314 aa) |
| | SEL59527.1 | Aspartate kinase; Belongs to the aspartokinase family. (415 aa) |
| | SEL59559.1 | L-amino acid N-acyltransferase YncA. (160 aa) |
| | SEL60663.1 | FR47-like protein. (228 aa) |
| | SEL60864.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (320 aa) |
| | SEL66644.1 | Hypothetical protein. (103 aa) |
| | SEL50552.1 | Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (239 aa) |
| | SEL48344.1 | Transposase. (322 aa) |
| | SEL75387.1 | Cystathionine beta-synthase. (346 aa) |
| | SEL78481.1 | Histidinol-phosphate aminotransferase. (371 aa) |
| | ilvD | Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (558 aa) |
| | SEL78774.1 | Acetolactate synthase, large subunit. (577 aa) |
| | SEL78870.1 | Acetolactate synthase, small subunit. (181 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (491 aa) |
| | ilvA | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (421 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (351 aa) |
| | SEL79128.1 | D-citramalate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (504 aa) |
| | SEL79169.1 | 3-isopropylmalate/(R)-2-methylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (198 aa) |
| | leuC | 3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (470 aa) |
| | SEL79479.1 | Glutamate synthase domain-containing protein 2; Belongs to the glutamate synthase family. (519 aa) |
| | SEL72529.1 | Ribose-phosphate pyrophosphokinase. (326 aa) |
| | SEL73823.1 | L-serine dehydratase; Belongs to the iron-sulfur dependent L-serine dehydratase family. (466 aa) |
| | SEL71856.1 | Asparagine synthase (glutamine-hydrolysing). (616 aa) |
| | SEL74851.1 | Acetyltransferase (GNAT) family protein. (152 aa) |
| | SEL75234.1 | L-threonine aldolase. (340 aa) |
| | pgk | Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (396 aa) |
| | SEL86150.1 | 2-keto-4-methylthiobutyrate aminotransferase apoenzyme. (385 aa) |
| | serC | Phosphoserine aminotransferase apoenzyme; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa) |
| | SEL95980.1 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (316 aa) |
| | SEL96882.1 | Cystathionine beta-lyase. (386 aa) |
| | SEL97087.1 | Septum formation protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (195 aa) |
| | SEL98043.1 | Branched-chain amino acid aminotransferase. (285 aa) |
| | SEL93648.1 | Serine O-acetyltransferase. (263 aa) |
| | SEL93686.1 | Cysteine synthase B; Belongs to the cysteine synthase/cystathionine beta- synthase family. (294 aa) |
| | hisI | phosphoribosyl-ATP pyrophosphatase; In the N-terminal section; belongs to the PRA-CH family. (207 aa) |
| | hisF | Cyclase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (251 aa) |
| | hisA | 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase. (242 aa) |
| | hisH | Glutamine amidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (193 aa) |
| | hisB | Imidazoleglycerol-phosphate dehydratase; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (380 aa) |
| | hisC | Histidinol-phosphate aminotransferase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (361 aa) |
| | hisD | Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (428 aa) |
| | hisG | ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (285 aa) |
| | SEL95084.1 | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (353 aa) |
| | SEM01245.1 | 3-dehydroquinate synthase. (386 aa) |
| | aroQ | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (138 aa) |
| | SEM07483.1 | Hypothetical protein. (98 aa) |
| | aroA | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (409 aa) |
| | gpmI | Phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (505 aa) |
| | SEM09207.1 | Aspartate aminotransferase. (396 aa) |
| | SEM09473.1 | Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (355 aa) |
| | SEM09897.1 | Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (216 aa) |
| | SEM13378.1 | Hypothetical protein. (98 aa) |
| | SEM13676.1 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (903 aa) |
| | SEM13704.1 | 5-methyltetrahydrofolate--homocysteine methyltransferase. (333 aa) |
| | SEM13410.1 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase. (360 aa) |
| | SEM14084.1 | Aspartate kinase. (1128 aa) |
| | SEM13441.1 | Prephenate dehydrogenase. (286 aa) |
| | metK | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (418 aa) |
| | SEM13472.1 | Aspartate/methionine/tyrosine aminotransferase. (381 aa) |
| | SEM13505.1 | Prephenate dehydratase. (275 aa) |
| | SEM16083.1 | Glutamate synthase (NADH) large subunit. (1502 aa) |
| | SEM16116.1 | Glutamate synthase (NADH) small subunit. (488 aa) |
| | SEM18497.1 | Shikimate dehydrogenase. (250 aa) |
| | SEM18650.1 | Acetylornithine/succinyldiaminopimelate/putresci ne aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (391 aa) |
| | SEM20543.1 | WbqC-like protein family protein. (207 aa) |
| | dapB | Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (233 aa) |
| | SEM22609.1 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa) |
| | pfkA | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa) |
| | SEM25643.1 | Anthranilate synthase component 1. (465 aa) |
| | SEM25674.1 | Anthranilate synthase component 2. (187 aa) |
| | trpD | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (331 aa) |
| | trpC | Indole-3-glycerol phosphate synthase; Belongs to the TrpC family. (270 aa) |
| | trpF | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (201 aa) |
| | trpB | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (394 aa) |
| | trpA | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (254 aa) |
| | SEM27095.1 | Aspartate aminotransferase. (396 aa) |
| | SEM27315.1 | Glyceraldehyde 3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (336 aa) |
| | SEM29329.1 | Ribose 5-phosphate isomerase B. (143 aa) |
| | trpF-2 | Phosphoribosylanthranilate isomerase; Belongs to the TrpF family. (217 aa) |
| | SEM33814.1 | Transposase. (357 aa) |
