STRINGSTRING
AKH65385.1 AKH65385.1 AKH62115.1 AKH62115.1 AKH62172.1 AKH62172.1 AKH62411.1 AKH62411.1 AKH62412.1 AKH62412.1 AKH62413.1 AKH62413.1 AKH62414.1 AKH62414.1 AKH62645.1 AKH62645.1 AKH65751.1 AKH65751.1 AKH62702.1 AKH62702.1 AKH63284.1 AKH63284.1 AKH63285.1 AKH63285.1 AKH63706.1 AKH63706.1 AKH63786.1 AKH63786.1 nqrF nqrF nqrE nqrE nqrB nqrB AKH64051.1 AKH64051.1 dipZ dipZ AKH64080.1 AKH64080.1 AKH64081.1 AKH64081.1 AKH64297.1 AKH64297.1 AKH64332.1 AKH64332.1 sdhB sdhB sdhA sdhA AKH64340.1 AKH64340.1 AKH64504.1 AKH64504.1 AKH64539.1 AKH64539.1 nuoA nuoA nuoB nuoB nuoC nuoC AKH64653.1 AKH64653.1 AKH64654.1 AKH64654.1 AKH64655.1 AKH64655.1 AKH64658.1 AKH64658.1 nuoK nuoK AKH64660.1 AKH64660.1 AKH64661.1 AKH64661.1 nuoN nuoN AKH64683.1 AKH64683.1 dld dld dsbB dsbB rnfE rnfE rnfG rnfG rnfD rnfD rnfC rnfC rnfB rnfB AKH65418.1 AKH65418.1 rnfA rnfA AKH65215.1 AKH65215.1 AKH65326.1 AKH65326.1 azoR azoR
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AKH65385.1Cytochrome B561; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
AKH62115.12Fe-2S ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa)
AKH62172.1Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (176 aa)
AKH62411.1Cytochrome C oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
AKH62412.1Cytochrome o ubiquinol oxidase subunit III; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
AKH62413.1Cytochrome o ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heme-copper respiratory oxidase family. (663 aa)
AKH62414.1Ubiquinol oxidase subunit II; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
AKH62645.1Formate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AKH65751.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (803 aa)
AKH62702.1Flavodoxin; An electron-transfer protein; flavodoxin binds one FMN molecule, which serves as a redox-active prosthetic group; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
AKH63284.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (803 aa)
AKH63285.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (195 aa)
AKH63706.1Ribonucleoside-triphosphate reductase; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (154 aa)
AKH63786.1Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
nqrFNa(+)-translocating NADH-quinone reductase subunit F; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway. (408 aa)
nqrENa(+)-translocating NADH-quinone reductase subunit E; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol; Belongs to the NqrDE/RnfAE family. (198 aa)
nqrBNa(+)-translocating NADH-quinone reductase subunit B; NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol. (412 aa)
AKH64051.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
dipZThiol:disulfide interchange protein precursor; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (575 aa)
AKH64080.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
AKH64081.1Part of four member fumarate reductase enzyme complex FrdABCD which catalyzes the reduction of fumarate to succinate during anaerobic respiration; FrdAB are the catalytic subcomplex consisting of a flavoprotein subunit and an iron-sulfur subunit, respectively; FrdCD are the membrane components which interact with quinone and are involved in electron transfer; the catalytic subunits are similar to succinate dehydrogenase SdhAB; Derived by automated computational analysis using gene prediction method: Protein Homology. (596 aa)
AKH64297.1Flavodoxin FldB; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (172 aa)
AKH64332.1Cytochrome d terminal oxidase subunit 1; Part of the aerobic respiratory chain; catalyzes the ubiquinol to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa)
AKH64340.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
AKH64504.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
AKH64539.1Glutaredoxin; Functions as an electron carrier in the glutathione-dependent synthesis of deoxyribonucleotides by the enzyme ribonucleotide reductase; also involved in reducing some disulfides in a coupled system with glutathione reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
nuoANADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (149 aa)
nuoBNADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa)
nuoCNADH:ubiquinone oxidoreductase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (598 aa)
AKH64653.1NADH dehydrogenase; Catalyzes the transfer of electrons from NADH to quinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
AKH64654.1NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (454 aa)
AKH64655.1NADH dehydrogenase; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (911 aa)
AKH64658.1NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (181 aa)
nuoKNADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa)
AKH64660.1NADH:ubiquinone oxidoreductase subunit L; Catalyzes the transfer of electrons from NADH to ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology. (615 aa)
AKH64661.1NADH:ubiquinone oxidoreductase subunit M; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
nuoNNADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa)
AKH64683.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
dldLactate dehydrogenase; Catalyzes the oxidation of D-lactate to pyruvate. Belongs to the quinone-dependent D-lactate dehydrogenase family. (571 aa)
dsbBDisulfide bond formation protein B; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (169 aa)
rnfEElongation factor G; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (232 aa)
rnfGElectron transporter RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (209 aa)
rnfDElectron transporter RnfD; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (359 aa)
rnfCElectron transporter RnfC; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfC subfamily. (744 aa)
rnfBElectron transporter RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (210 aa)
AKH65418.1Cytochrome D ubiquinol oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
rnfAElectron transporter RsxA; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa)
AKH65215.1DMSO reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (803 aa)
AKH65326.1Dialkylrecorsinol condensing enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
azoRFMN-dependent NADH-azoreductase; Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity; Belongs to the azoreductase type 1 family. (200 aa)
Your Current Organism:
Photorhabdus thracensis
NCBI taxonomy Id: 230089
Other names: CIP 108426, DSM 15199, NCIMB 13952, P. thracensis, Photorhabdus luminescens subsp. thracensis, Photorhabdus luminescens subsp. thracensis Hazir et al. 2004, Photorhabdus temperata subsp. thracensis, Photorhabdus temperata subsp. thracensis (Hazir et al. 2004) Tailliez et al. 2010, strain 39-8
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.