(74 nodes) Glutathione metabolism network (Coprinopsis marcescibilis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	A0A5C3KWR6	Acyl-CoA N-acyltransferase. (321 aa)
	A0A5C3KWS6	Acyl-CoA N-acyltransferase. (245 aa)
	A0A5C3KXT7	Uncharacterized protein. (912 aa)
	A0A5C3KXZ2	Uncharacterized protein. (237 aa)
	A0A5C3KY75	Thioredoxin-like protein. (216 aa)
	A0A5C3KY88	Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family. (502 aa)
	A0A5C3L030	Uncharacterized protein. (157 aa)
	A0A5C3L0C0	Aminopeptidase. (897 aa)
	A0A5C3L0L1	Glutamate-cysteine ligase catalytic subunit. (682 aa)
	A0A5C3L0Y3	Gamma-glutamyltranspeptidase. (618 aa)
	A0A5C3L136	RraA-like protein. (229 aa)
	A0A5C3L172	Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (473 aa)
	A0A5C3L2B8	Uncharacterized protein. (653 aa)
	A0A5C3L2H1	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (370 aa)
	A0A5C3L361	Glutathione S-transferase; Belongs to the GST superfamily. (214 aa)
	A0A5C3L384	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (358 aa)
	A0A5C3L3H5	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (368 aa)
	A0A5C3L3N3	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (397 aa)
	A0A5C3L3Q5	RNI-like protein. (1013 aa)
	A0A5C3L3Z3	Glutathione S-transferase; Belongs to the GST superfamily. (218 aa)
	A0A5C3L4W7	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (165 aa)
	A0A5C3L4Y3	Ribonucleotide reductase. (341 aa)
	A0A5C3L505	Glutathione synthetase. (540 aa)
	A0A5C3L511	Glutathione S-transferase; Belongs to the GST superfamily. (218 aa)
	A0A5C3L597	DnaJ-domain-containing protein. (536 aa)
	A0A5C3L5H3	Glutathione S-transferase; Belongs to the GST superfamily. (216 aa)
	A0A5C3L5M1	Glutathione S-transferase; Belongs to the GST superfamily. (216 aa)
	A0A5C3L743	Cysteine peroxiredoxin. (222 aa)
	A0A5C3L752	Glutathione S-transferase; Belongs to the GST superfamily. (215 aa)
	A0A5C3L760	Thioredoxin-like protein; Belongs to the GST superfamily. (220 aa)
	A0A5C3L762	Glutathione S-transferase; Belongs to the GST superfamily. (212 aa)
	A0A5C3L9L1	Fe2OG dioxygenase domain-containing protein. (262 aa)
	A0A5C3LAC0	Glutaredoxin domain-containing protein. (261 aa)
	A0A5C3LB30	SAP domain-containing protein. (226 aa)
	A0A5C3LC12	GGACT domain-containing protein. (188 aa)
	A0A5C3LCA5	Nucleotide-sugar transporter. (485 aa)
	A0A5C3LDA5	Lincomycin-condensing protein lmbA. (580 aa)
	A0A5C3L9J8	CNDP dipeptidase. (475 aa)
	A0A5C3LDF6	Membrane-associated proteins in eicosanoid and glutathione metabolism. (151 aa)
	A0A5C3LDJ0	MAPEG-domain-containing protein. (181 aa)
	A0A5C3LDV3	YTH-domain-containing protein. (800 aa)
	A0A5C3LG30	Uncharacterized protein. (444 aa)
	A0A5C3LPI9	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (491 aa)
	A0A5C3L763	Ribonucleotide reductase small subunit. (361 aa)
	A0A5C3KAT7	Glyceraldehyde-3-phosphate dehydrogenase-like protein. (511 aa)
	A0A5C3KBJ0	Uncharacterized protein. (433 aa)
	A0A5C3KBQ4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (871 aa)
	A0A5C3KC46	Ribonucleotide reductase. (199 aa)
	A0A5C3KCW3	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (373 aa)
	A0A5C3KE13	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (370 aa)
	A0A5C3KF35	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (733 aa)
	A0A5C3KGJ0	Sphingolipid C9-methyltransferase. (482 aa)
	A0A5C3KI58	Mismatched base pair and cruciform DNA recognition protein. (105 aa)
	A0A5C3KIS0	Uncharacterized protein. (113 aa)
	A0A5C3KLP4	Glutaredoxin. (117 aa)
	A0A5C3KMJ8	Spermidine synthase; Belongs to the spermidine/spermine synthase family. (748 aa)
	A0A5C3KMM5	Uncharacterized protein; Belongs to the GST superfamily. (239 aa)
	A0A5C3L8X1	Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (417 aa)
	A0A5C3L8H9	Uncharacterized protein. (271 aa)
	A0A5C3L8A0	5-oxoprolinase. (805 aa)
	A0A5C3L898	Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
	A0A5C3L7X1	Ribonucleotide reductase small subunit. (408 aa)
	A0A5C3L7G6	Uncharacterized protein; Belongs to the GST superfamily. (294 aa)
	A0A5C3KMN2	Leucine aminopeptidase. (489 aa)
	A0A5C3KN98	Peroxidase; Belongs to the peroxidase family. (384 aa)
	A0A5C3KQN2	Prefoldin subunit 5. (163 aa)
	A0A5C3KR22	CsbD domain-containing protein. (110 aa)
	A0A5C3KRP1	CsbD domain-containing protein. (102 aa)
	A0A5C3KSR4	Peroxidase; Belongs to the peroxidase family. Ligninase subfamily. (383 aa)
	A0A5C3KSZ7	Gamma-glutamylcyclotransferase; Catalyzes the cleavage of glutathione into 5-oxo-L-proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides; Belongs to the gamma-glutamylcyclotransferase family. (202 aa)
	A0A5C3KU10	Cytoplasmic protein. (582 aa)
	A0A5C3KUT0	Thioredoxin-like protein. (170 aa)
	A0A5C3KVG9	Acyl-CoA N-acyltransferase. (246 aa)
	A0A5C3KW53	Uncharacterized protein. (907 aa)

Your Current Organism:

Coprinopsis marcescibilis

NCBI taxonomy Id: 230819
Other names: C. marcescibilis, Coprinopsis marcescibilis (Britzelm.) Oerstadius & E. Larss. 2008, Psathyrella marcescibilis

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
A0A5C3KAT7	A0A5C3KBJ0	Glyceraldehyde-3-phosphate dehydrogenase-like protein.	Uncharacterized protein.	0.551
A0A5C3KAT7	A0A5C3KY88	Glyceraldehyde-3-phosphate dehydrogenase-like protein.	Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.850
A0A5C3KBJ0	A0A5C3KAT7	Uncharacterized protein.	Glyceraldehyde-3-phosphate dehydrogenase-like protein.	0.551
A0A5C3KBJ0	A0A5C3KMJ8	Uncharacterized protein.	Spermidine synthase; Belongs to the spermidine/spermine synthase family.	0.578
A0A5C3KBJ0	A0A5C3KY88	Uncharacterized protein.	Ornithine decarboxylase; Belongs to the Orn/Lys/Arg decarboxylase class-II family.	0.888
A0A5C3KBQ4	A0A5C3KC46	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleotide reductase.	0.976
A0A5C3KBQ4	A0A5C3KLP4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Glutaredoxin.	0.933
A0A5C3KBQ4	A0A5C3KY75	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Thioredoxin-like protein.	0.933
A0A5C3KBQ4	A0A5C3L4W7	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.594
A0A5C3KBQ4	A0A5C3L4Y3	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleotide reductase.	0.977
A0A5C3KBQ4	A0A5C3L763	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleotide reductase small subunit.	0.976
A0A5C3KBQ4	A0A5C3L7X1	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleotide reductase small subunit.	0.976
A0A5C3KBQ4	A0A5C3LAC0	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Glutaredoxin domain-containing protein.	0.931
A0A5C3KC46	A0A5C3KBQ4	Ribonucleotide reductase.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.976
A0A5C3KC46	A0A5C3KF35	Ribonucleotide reductase.	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	0.976
A0A5C3KC46	A0A5C3L4W7	Ribonucleotide reductase.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.490
A0A5C3KF35	A0A5C3KC46	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Ribonucleotide reductase.	0.976
A0A5C3KF35	A0A5C3KLP4	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Glutaredoxin.	0.933
A0A5C3KF35	A0A5C3KY75	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Thioredoxin-like protein.	0.933
A0A5C3KF35	A0A5C3L4W7	Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.	Glutathione peroxidase; Belongs to the glutathione peroxidase family.	0.594