STRINGSTRING
argH argH gap gap accB accB asd asd dapA dapA CB0101_08175 CB0101_08175 purT purT argG argG aroE aroE rfbB rfbB rfbD rfbD rfbC rfbC CB0101_08690 CB0101_08690 ribH ribH CB0101_08640 CB0101_08640 purF purF purL purL CB0101_08605 CB0101_08605 miaA miaA cysE cysE acpP acpP tkt tkt CB0101_09160 CB0101_09160 CB0101_09070 CB0101_09070 CB0101_09320 CB0101_09320 CB0101_09285 CB0101_09285 hisB hisB fabI fabI bchD bchD CB0101_09370 CB0101_09370 CB0101_09360 CB0101_09360 CB0101_09355 CB0101_09355 aroC aroC sat sat CB0101_09930 CB0101_09930 CB0101_09765 CB0101_09765 leuC leuC glyA glyA ispH ispH purH purH metK metK CB0101_10305 CB0101_10305 CB0101_10165 CB0101_10165 pheA pheA dapL dapL adk adk CB0101_10610 CB0101_10610 CB0101_10530 CB0101_10530 hemF hemF purM purM panC/cmk panC/cmk CB0101_11125 CB0101_11125 CB0101_11045 CB0101_11045 aroK aroK CB0101_10995 CB0101_10995 zds zds aroQ aroQ CB0101_11195 CB0101_11195 hemB hemB gluQ gluQ plsY plsY proC proC hisD hisD rpiA rpiA purC purC purD purD CB0101_06605 CB0101_06605 gpmI gpmI CB0101_06930 CB0101_06930 pdhA pdhA ispF ispF CB0101_06160 CB0101_06160 surE surE ribD ribD argF argF CB0101_06380 CB0101_06380 CB0101_05585 CB0101_05585 hemL hemL gltX gltX dxr dxr hisI hisI CB0101_00480 CB0101_00480 alsS alsS asnB asnB acsF acsF CB0101_00300 CB0101_00300 hemN hemN CB0101_00165 CB0101_00165 trpA trpA CB0101_01125 CB0101_01125 CB0101_00955 CB0101_00955 CB0101_00900 CB0101_00900 CB0101_00895 CB0101_00895 CB0101_01150 CB0101_01150 ubiX ubiX acsF-2 acsF-2 ispG ispG CB0101_01580 CB0101_01580 dapB dapB CB0101_01410 CB0101_01410 tpiA tpiA cysK cysK CB0101_01240 CB0101_01240 proB proB leuB leuB accD accD fba fba CB0101_01755 CB0101_01755 CB0101_01730 CB0101_01730 hisA hisA fumC fumC CB0101_01850 CB0101_01850 purN purN argC argC ribA ribA CB0101_02605 CB0101_02605 hisZ hisZ CB0101_02540 CB0101_02540 CB0101_02535 CB0101_02535 dxs dxs ilvA ilvA pyk pyk purK purK aroB aroB CB0101_02185 CB0101_02185 CB0101_02100 CB0101_02100 CB0101_02080 CB0101_02080 gpsA gpsA metH metH ilvE ilvE hemJ hemJ dapF dapF pgi pgi sds sds acs acs trpD trpD ispE ispE CB0101_03425 CB0101_03425 CB0101_03345 CB0101_03345 pcyA pcyA chlP chlP CB0101_03175 CB0101_03175 glpX glpX hemA hemA CB0101_03160 CB0101_03160 gndA gndA pgl pgl ilvD ilvD purS purS purQ purQ CB0101_03050 CB0101_03050 argB argB hemC hemC hemE hemE glgB glgB CB0101_03870 CB0101_03870 proA proA thrB thrB glk glk menD menD menB menB glgA glgA aroA aroA CB0101_03655 CB0101_03655 hemH hemH tal tal CB0101_04155 CB0101_04155 nifJ nifJ ppsA ppsA hisG hisG CB0101_04850 CB0101_04850 cbbL cbbL chlN chlN chlB chlB chlL chlL CB0101_04615 CB0101_04615 trpF trpF accA accA CB0101_05155 CB0101_05155 gcvT gcvT cobA cobA CB0101_08060 CB0101_08060 acnB acnB gcvP gcvP gcvH gcvH CB0101_07560 CB0101_07560 CB0101_07640 CB0101_07640 eno eno argJ argJ ndk ndk pgk pgk plsX plsX fabD fabD CB0101_14640 CB0101_14640 CB0101_14675 CB0101_14675 pds pds cugP cugP CB0101_14775 CB0101_14775 trpB trpB purE purE CB0101_14845 CB0101_14845 CB0101_14900 CB0101_14900 CB0101_14910 CB0101_14910 menC menC menA menA CB0101_14925 CB0101_14925 CB0101_14970 CB0101_14970 CB0101_14985 CB0101_14985 CB0101_14370 CB0101_14370 CB0101_14295 CB0101_14295 accC accC mqo mqo argD argD panB panB ilvC ilvC ubiE ubiE hisF hisF chlG chlG trpC trpC lpdA lpdA plqA plqA ispD ispD fabG fabG ctaB ctaB CB0101_13310 CB0101_13310 CB0101_13340 CB0101_13340 aroH aroH zwf zwf CB0101_12905 CB0101_12905 leuA leuA CB0101_13000 CB0101_13000 CB0101_13010 CB0101_13010 CB0101_13030 CB0101_13030 hisH hisH bchI bchI CB0101_13110 CB0101_13110 malQ malQ prs prs gap-2 gap-2 CB0101_12760 CB0101_12760 CB0101_12660 CB0101_12660 lysA lysA CB0101_12530 CB0101_12530 CB0101_12435 CB0101_12435 crtH crtH ilvN ilvN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
argHUnannotated protein. (466 aa)
gapUnannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
accBUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (157 aa)
asdUnannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (358 aa)
dapAUnannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (306 aa)
CB0101_08175Unannotated protein. (706 aa)
purTUnannotated protein; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (396 aa)
argGUnannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
aroEUnannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (98 aa)
rfbBUnannotated protein; Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily. (362 aa)
rfbDUnannotated protein; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (299 aa)
rfbCUnannotated protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (205 aa)
CB0101_08690Unannotated protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (298 aa)
ribHUnannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (159 aa)
CB0101_08640Unannotated protein. (617 aa)
purFUnannotated protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (525 aa)
purLUnannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (784 aa)
CB0101_08605Unannotated protein; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (352 aa)
miaAUnannotated protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (311 aa)
cysEUnannotated protein. (250 aa)
acpPUnannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (80 aa)
tktUnannotated protein; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (671 aa)
CB0101_09160Unannotated protein. (329 aa)
CB0101_09070Unannotated protein. (336 aa)
CB0101_09320Unannotated protein. (397 aa)
CB0101_09285Unannotated protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (841 aa)
hisBUnannotated protein. (211 aa)
fabIUnannotated protein. (260 aa)
bchDUnannotated protein; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (707 aa)
CB0101_09370Unannotated protein. (219 aa)
CB0101_09360Unannotated protein. (476 aa)
CB0101_09355Unannotated protein. (451 aa)
aroCUnannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa)
satUnannotated protein. (388 aa)
CB0101_09930Unannotated protein. (341 aa)
CB0101_09765Unannotated protein; Belongs to the LeuD family. (211 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (469 aa)
glyAUnannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (429 aa)
ispHUnannotated protein; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (402 aa)
purHUnannotated protein. (521 aa)
metKUnannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (422 aa)
CB0101_10305Unannotated protein. (263 aa)
CB0101_10165Unannotated protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family. (329 aa)
pheAUnannotated protein. (291 aa)
dapLUnannotated protein; Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL- diaminopimelate. (416 aa)
adkUnannotated protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (182 aa)
CB0101_10610Unannotated protein. (296 aa)
CB0101_10530Unannotated protein. (506 aa)
hemFUnannotated protein; Involved in the heme and chlorophyll biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX. (361 aa)
purMUnannotated protein. (344 aa)
panC/cmkUnannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the N-terminal section; belongs to the pantothenate synthetase family. (518 aa)
CB0101_11125Unannotated protein. (269 aa)
CB0101_11045Unannotated protein. (213 aa)
aroKUnannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (207 aa)
CB0101_10995Unannotated protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (270 aa)
zdsUnannotated protein; Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'. (497 aa)
aroQUnannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (170 aa)
CB0101_11195Unannotated protein; Belongs to the aldehyde dehydrogenase family. (458 aa)
hemBUnannotated protein; Belongs to the ALAD family. (333 aa)
gluQUnannotated protein; Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5-dihydroxy-2- cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon; Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily. (323 aa)
plsYUnannotated protein; Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP. (214 aa)
proCUnannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (271 aa)
hisDUnannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (448 aa)
rpiAUnannotated protein; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (237 aa)
purCUnannotated protein; Belongs to the SAICAR synthetase family. (251 aa)
purDUnannotated protein; Belongs to the GARS family. (433 aa)
CB0101_06605Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
gpmIUnannotated protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (524 aa)
CB0101_06930Unannotated protein; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (431 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (369 aa)
ispFUnannotated protein; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (161 aa)
CB0101_06160Unannotated protein; Belongs to the ribF family. (333 aa)
surEUnannotated protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (265 aa)
ribDUnannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (359 aa)
argFUnannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (316 aa)
CB0101_06380Unannotated protein. (283 aa)
CB0101_05585Unannotated protein. (490 aa)
hemLUnannotated protein. (429 aa)
gltXUnannotated protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (473 aa)
dxrUnannotated protein; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (416 aa)
hisIUnannotated protein; In the N-terminal section; belongs to the PRA-CH family. (231 aa)
CB0101_00480Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
alsSUnannotated protein; Belongs to the TPP enzyme family. (547 aa)
asnBUnannotated protein. (687 aa)
acsFUnannotated protein; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (334 aa)
CB0101_00300Unannotated protein. (230 aa)
hemNUnannotated protein; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (453 aa)
CB0101_00165Unannotated protein. (306 aa)
trpAUnannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (270 aa)
CB0101_01125Unannotated protein. (725 aa)
CB0101_00955Unannotated protein. (275 aa)
CB0101_00900Unannotated protein. (326 aa)
CB0101_00895Unannotated protein. (272 aa)
CB0101_01150Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (341 aa)
ubiXUnannotated protein; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (199 aa)
acsF-2Unannotated protein; Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME); Belongs to the AcsF family. (364 aa)
ispGUnannotated protein; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (408 aa)
CB0101_01580Unannotated protein. (397 aa)
dapBUnannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (285 aa)
CB0101_01410Unannotated protein. (1333 aa)
tpiAUnannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (235 aa)
cysKUnannotated protein; Belongs to the cysteine synthase/cystathionine beta- synthase family. (325 aa)
CB0101_01240Unannotated protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (845 aa)
proBUnannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (359 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (361 aa)
accDUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (291 aa)
fbaUnannotated protein; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (357 aa)
CB0101_01755Unannotated protein. (433 aa)
CB0101_01730Unannotated protein. (282 aa)
hisAUnannotated protein. (331 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (458 aa)
CB0101_01850Unannotated protein; Belongs to the AB hydrolase superfamily. MetX family. (329 aa)
purNUnannotated protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (191 aa)
argCUnannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (354 aa)
ribAUnannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (517 aa)
CB0101_02605Unannotated protein; Belongs to the inositol monophosphatase superfamily. (300 aa)
hisZUnannotated protein; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine. (392 aa)
CB0101_02540Unannotated protein. (578 aa)
CB0101_02535Unannotated protein. (512 aa)
dxsUnannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (635 aa)
ilvAUnannotated protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (527 aa)
pykUnannotated protein; Belongs to the pyruvate kinase family. (485 aa)
purKUnannotated protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR); Belongs to the PurK/PurT family. (423 aa)
aroBUnannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (372 aa)
CB0101_02185Unannotated protein. (360 aa)
CB0101_02100Unannotated protein; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (796 aa)
CB0101_02080Unannotated protein. (232 aa)
gpsAUnannotated protein; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (308 aa)
metHUnannotated protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1212 aa)
ilvEUnannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (305 aa)
hemJUnannotated protein. (197 aa)
dapFUnannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (395 aa)
pgiUnannotated protein; Belongs to the GPI family. (497 aa)
sdsUnannotated protein; Belongs to the FPP/GGPP synthase family. (323 aa)
acsUnannotated protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (664 aa)
trpDUnannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (344 aa)
ispEUnannotated protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (310 aa)
CB0101_03425Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)
CB0101_03345Unannotated protein. (396 aa)
pcyAUnannotated protein; Catalyzes the four-electron reduction of biliverdin IX-alpha (2-electron reduction at both the A and D rings); the reaction proceeds via an isolatable 2-electron intermediate, 181,182-dihydrobiliverdin. Belongs to the HY2 family. (243 aa)
chlPUnannotated protein. (460 aa)
CB0101_03175Unannotated protein; Belongs to the ribulose-phosphate 3-epimerase family. (227 aa)
glpXUnannotated protein; Belongs to the FBPase class 2 family. (334 aa)
hemAUnannotated protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (434 aa)
CB0101_03160Unannotated protein; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (431 aa)
gndAUnannotated protein; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (471 aa)
pglUnannotated protein; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (563 aa)
purSUnannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (89 aa)
purQUnannotated protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the amm [...] (217 aa)
CB0101_03050Unannotated protein. (332 aa)
argBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa)
hemCUnannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (317 aa)
hemEUnannotated protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (352 aa)
glgBUnannotated protein; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (773 aa)
CB0101_03870Unannotated protein. (296 aa)
proAUnannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (443 aa)
thrBUnannotated protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (320 aa)
glkUnannotated protein; Belongs to the bacterial glucokinase family. (332 aa)
menDUnannotated protein; Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2- succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC). Belongs to the TPP enzyme family. MenD subfamily. (604 aa)
menBUnannotated protein; Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2- naphthoyl-CoA (DHNA-CoA). (286 aa)
glgAUnannotated protein; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (513 aa)
aroAUnannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (435 aa)
CB0101_03655Unannotated protein; Belongs to the UbiD family. (290 aa)
hemHUnannotated protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (391 aa)
talUnannotated protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 1 subfamily. (390 aa)
CB0101_04155Unannotated protein; Belongs to the phosphoglycerate mutase family. (450 aa)
nifJUnannotated protein; Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin. (1180 aa)
ppsAUnannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (800 aa)
hisGUnannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (215 aa)
CB0101_04850Unannotated protein. (113 aa)
cbbLUnannotated protein; RuBisCO catalyzes two reactions: the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate in the photorespiration process. Both reactions occur simultaneously and in competition at the same active site. Belongs to the RuBisCO large chain family. Type I subfamily. (470 aa)
chlNUnannotated protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (425 aa)
chlBUnannotated protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein (ChlN-ChlB) is the catalytic component of the complex. (532 aa)
chlLUnannotated protein; Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The L component serves as a unique electron donor to the NB-component of the complex, and binds Mg-ATP. (307 aa)
CB0101_04615Unannotated protein; Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide). (331 aa)
trpFUnannotated protein; Belongs to the TrpF family. (230 aa)
accAUnannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (329 aa)
CB0101_05155Unannotated protein; Belongs to the mannose-6-phosphate isomerase type 2 family. (488 aa)
gcvTUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. (379 aa)
cobAUnannotated protein; Belongs to the precorrin methyltransferase family. (264 aa)
CB0101_08060Unannotated protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (357 aa)
acnBUnannotated protein; Belongs to the aconitase/IPM isomerase family. (871 aa)
gcvPUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (987 aa)
gcvHUnannotated protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
CB0101_07560Unannotated protein. (200 aa)
CB0101_07640Unannotated protein. (303 aa)
enoUnannotated protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (430 aa)
argJUnannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
ndkUnannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (151 aa)
pgkUnannotated protein; Belongs to the phosphoglycerate kinase family. (401 aa)
plsXUnannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (446 aa)
fabDUnannotated protein. (296 aa)
CB0101_14640Unannotated protein. (259 aa)
CB0101_14675Unannotated protein. (307 aa)
pdsUnannotated protein. (462 aa)
cugPUnannotated protein; Catalyzes the formation of UDP-glucose, from UTP and glucose 1-phosphate. (393 aa)
CB0101_14775Unannotated protein; Belongs to the citrate synthase family. (390 aa)
trpBUnannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (441 aa)
purEUnannotated protein; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (176 aa)
CB0101_14845Unannotated protein. (241 aa)
CB0101_14900Unannotated protein; Catalyzes the hydrolysis of 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA) to 1,4-dihydroxy-2-naphthoate (DHNA), a reaction involved in phylloquinone (vitamin K1) biosynthesis; Belongs to the 4-hydroxybenzoyl-CoA thioesterase family. DHNA-CoA hydrolase subfamily. (149 aa)
CB0101_14910Unannotated protein. (410 aa)
menCUnannotated protein; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (325 aa)
menAUnannotated protein; Involved in the synthesis of phylloquinone (vitamin K1). Catalyzes the transfer of a prenyl chain to 2-carboxy-1,4- naphthoquinone; Belongs to the MenA family. Type 2 subfamily. (287 aa)
CB0101_14925Unannotated protein. (477 aa)
CB0101_14970Unannotated protein. (173 aa)
CB0101_14985Unannotated protein. (373 aa)
CB0101_14370Unannotated protein. (390 aa)
CB0101_14295Unannotated protein. (546 aa)
accCUnannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
mqoUnannotated protein. (485 aa)
argDUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (220 aa)
panBUnannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (290 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (331 aa)
ubiEUnannotated protein; Methyltransferase required for the conversion of 2-phytyl- 1,4-beta-naphthoquinol to phylloquinol. (238 aa)
hisFUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (257 aa)
chlGUnannotated protein. (335 aa)
trpCUnannotated protein; Belongs to the TrpC family. (294 aa)
lpdAUnannotated protein. (480 aa)
plqAUnannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of plastoquinone-9 (PQ-9) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 4-hydroxy-3-solanesylbenzoate. Belongs to the UbiA prenyltransferase family. (301 aa)
ispDUnannotated protein; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (227 aa)
fabGUnannotated protein; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (250 aa)
ctaBUnannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (323 aa)
CB0101_13310Unannotated protein. (307 aa)
CB0101_13340Unannotated protein. (223 aa)
aroHUnannotated protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. Probably involved in the aromatic amino acid biosynthesis. (123 aa)
zwfUnannotated protein; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (507 aa)
CB0101_12905Unannotated protein; Belongs to the FPP/GGPP synthase family. (303 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (546 aa)
CB0101_13000Unannotated protein; Belongs to the glycosyl hydrolase 57 family. (536 aa)
CB0101_13010Unannotated protein. (418 aa)
CB0101_13030Unannotated protein. (387 aa)
hisHUnannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (208 aa)
bchIUnannotated protein; Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX. (361 aa)
CB0101_13110Unannotated protein. (436 aa)
malQUnannotated protein. (495 aa)
prsUnannotated protein; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (331 aa)
gap-2Unannotated protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
CB0101_12760Unannotated protein; Belongs to the CDS family. (302 aa)
CB0101_12660Unannotated protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (264 aa)
lysAUnannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (466 aa)
CB0101_12530Unannotated protein. (123 aa)
CB0101_12435Unannotated protein. (496 aa)
crtHUnannotated protein. (545 aa)
ilvNUnannotated protein. (176 aa)
Your Current Organism:
Synechococcus sp. CB0101
NCBI taxonomy Id: 232348
Other names: S. sp. CB0101
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