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| | proC | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (273 aa) |
| | bfrA | Bacterioferritin; Iron-storage protein, whose ferroxidase center binds Fe(2+) ions, oxidizes them by dioxygen to Fe(3+), and participates in the subsequent Fe(3+) oxide mineral core formation within the central cavity of the protein complex; Belongs to the bacterioferritin family. (159 aa) |
| | yhcB | Putative cytochrome d ubiquinol oxidase subunit III (Cytochrome bd-I oxidase subunit III); COG3105 Uncharacterized protein conserved in bacteria. (134 aa) |
| | gltD | COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases. (472 aa) |
| | yhaK | Pirin-like protein YhaK; COG1741 Pirin-related protein; Belongs to the pirin family. (242 aa) |
| | yqjF | COG2259 Predicted membrane protein. (131 aa) |
| | yaiW | DUF2382 domain-containing protein; Potential frameshift: common BLAST hit: gi|291616779|ref|YP_003519521.1| YaiW; Putative outer membrane lipoprotein. (163 aa) |
| | asd | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa) |
| | aroE | Shikimate dehydrogenase (NADP(+)); Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (272 aa) |
| | rffD | UDP-glucose dehydrogenase; Catalyzes the four-electron oxidation of UDP-N-acetyl-D- mannosamine (UDP-ManNAc), reducing NAD(+) and releasing UDP-N- acetylmannosaminuronic acid (UDP-ManNAcA); Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. WecC subfamily. (420 aa) |
| | trxA | Thioredoxin 1; COG0526 Thiol-disulfide isomerase and thioredoxins; Belongs to the thioredoxin family. (108 aa) |
| | ilvC | Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (492 aa) |
| | dps | DNA starvation/stationary phase protection protein Dps; COG0783 DNA-binding ferritin-like protein (oxidative damage protectant); Belongs to the Dps family. (167 aa) |
| | yliI | Soluble aldose sugar dehydrogenase PQQ-dependent; COG2133 Glucose/sorbosone dehydrogenases. (378 aa) |
| | AHF73164.1 | COG2259 Predicted membrane protein. (144 aa) |
| | ygiN | YgiN protein involved in menadione metabolism. (104 aa) |
| | fldA | Flavodoxin FldA; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (171 aa) |
| | sdhC | COG2009 Succinate dehydrogenase/fumarate reductase, cytochrome b subunit. (129 aa) |
| | sdhD | Succinate dehydrogenase cytochrome b556 small membrane subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (113 aa) |
| | sdhA | COG1053 Succinate dehydrogenase/fumarate reductase, flavoprotein subunit; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (588 aa) |
| | sdhB | COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (238 aa) |
| | sucA | COG0567 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes. (935 aa) |
| | cydA | Cytochrome d ubiquinol oxidase subunit I; ISSoEn2, terminal inverted repeat. (522 aa) |
| | cydB | COG1294 Cytochrome bd-type quinol oxidase, subunit 2. (379 aa) |
| | ybgT | ybgT; COG4890 Predicted outer membrane lipoprotein. (37 aa) |
| | dipZ1 | Cytochrome c-type biogenesis protein DsbD protein-disulfide reductase; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily. (572 aa) |
| | tyrA | Bifunctional chorismate mutase/prephenate dehydrogenase; COG1605 Chorismate mutase. (373 aa) |
| | queH | Epoxyqueuosine reductase QueH; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (217 aa) |
| | ahpC | Alkyl hydroperoxide reductase subunit C-like protein; COG1113 Gamma-aminobutyrate permease and related permeases; putative proline-specific permease. (200 aa) |
| | grxC | Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (82 aa) |
| | gpsA | COG0240 Glycerol-3-phosphate dehydrogenase; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (338 aa) |
| | fpr | COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (248 aa) |
| | garR | 2-hydroxy-3-oxopropionate reductase; Catalyzes the reduction of tatronate semialdehyde to D- glycerate; Belongs to the HIBADH-related family. 2-hydroxy-3- oxopropionate reductase subfamily. (295 aa) |
| | cysJ | Sulfite reductase [NADPH] flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. Belongs to the NADPH-dependent sulphite reductase flavoprotein subunit CysJ family. In the N-terminal section; belongs to the flavodoxin family. (604 aa) |
| | cysI | Sulfite reductase [NADPH] hemoprotein beta-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (566 aa) |
| | cysH | Phosphoadenylyl-sulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (244 aa) |
| | cysG | Uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. (472 aa) |
| | dipZ2 | Cytochrome c-type biogenesis protein DsbD / protein-disulfide reductase; COG4232 Thiol:disulfide interchange protein. (572 aa) |
| | qor1 | Quinone oxidoreductase, NADPH-dependent; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (313 aa) |
| | mtnD | Acireductone dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. (181 aa) |
| | msrA | Peptide methionine sulfoxide reductase MsrA; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (213 aa) |
| | dusA | tRNA-dihydrouridine synthase A; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs; Belongs to the Dus family. DusA subfamily. (341 aa) |
| | qor2 | Quinone oxidoreductase, NADPH-dependent; COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (327 aa) |
| | SOPEG_1329 | OsmC family protein; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; alkansulfonate monooxygenase, putative. (177 aa) |
| | AHF73598.1 | COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (252 aa) |
| | thrA | Aspartokinase / Homoserine dehydrogenase; COG0527 Aspartokinases; In the C-terminal section; belongs to the homoserine dehydrogenase family. (816 aa) |
| | ispH | 4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. (316 aa) |
| | dapB | 4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (273 aa) |
| | folA | Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa) |
| | pdxA | 4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (330 aa) |
| | uxaB1 | COG0246 Mannitol-1-phosphate/altronate dehydrogenases. (483 aa) |
| | udg | COG1004 Predicted UDP-glucose 6-dehydrogenase. (447 aa) |
| | msrB | COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase; Belongs to the MsrB Met sulfoxide reductase family. (137 aa) |
| | gapA | COG0057 Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa) |
| | yeaE | Methylglyoxal reductase; Potential frameshift: common BLAST hit: gi|251789817|ref|YP_003004538.1| Aldose 1-epimerase; Aldose 1-epimerase. (284 aa) |
| | hmuV | Short-chain dehydrogenase/reductase SDR; COG4559 ABC-type hemin transport system, ATPase component; Hemin transport system ATP-binding protein hmuV; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (279 aa) |
| | aldH | Ketoglutarate semialdehyde dehydrogenase; COG2376 Dihydroxyacetone kinase; conserved hypothetical protein with Dak2 phosphatase domain. (527 aa) |
| | pyrD | Dihydroorotate dehydrogenase 2; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (336 aa) |
| | dsbB | Periplasmic thiol:disulfide oxidoreductase DsbB required for DsbA reoxidation; Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family. (176 aa) |
| | yebR | GAF domain-containing protein; COG2995 Uncharacterized paraquat-inducible protein A; hypothetical protein. (163 aa) |
| | SOPEG_1722 | VOC domain-containing protein; COG0583 Transcriptional regulator; LysR family regulatory protein. (141 aa) |
| | tadG | 2-Keto-D-gluconate dehydrogenase membrane-bound cytochrome c; Target site duplication generated by insertion of ISSoEn1. (447 aa) |
| | pqqE | Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ). (385 aa) |
| | tag | Flavin reductase-like protein; Potential frameshift: common BLAST hit: gi|292901116|ref|YP_003540485.1| DeoR family transcriptional regulator; DeoR family transcriptional regulator. (211 aa) |
| | gnd | 6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (468 aa) |
| | nrdF | Ribonucleotide reductase of class Ib (aerobic) beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (321 aa) |
| | nrdH | Glutaredoxin-like protein NrdH required for reduction of Ribonucleotide reductase class Ib; COG0695 Glutaredoxin and related proteins. (79 aa) |
| | ubiF | 3-demethoxyubiquinol 3-hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (393 aa) |
| | trxB | COG0492 Thioredoxin reductase. (322 aa) |
| | pflA | Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family. (246 aa) |
| | guaC | GMP reductase; Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides. (347 aa) |
| | leuB | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (394 aa) |
| | fabG | 3-oxoacyl-(acyl-carrier-protein) reductase; Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (244 aa) |
| | pntA1 | NAD(P) transhydrogenase subunit alpha; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (510 aa) |
| | pntB1 | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (454 aa) |
| | AHF74084.1 | Oxidoreductase short chain dehydrogenase/reductase family; COG0300 Short-chain dehydrogenases of various substrate specificities. (297 aa) |
| | katE | Hydroperoxidase II; Serves to protect cells from the toxic effects of hydrogen peroxide. (750 aa) |
| | kduD1 | 2-deoxy-D-gluconate 3-dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases). (253 aa) |
| | ndh | COG1252 NADH dehydrogenase, FAD-containing subunit. (434 aa) |
| | rsxA | Ion-translocating oxidoreductase complex subunit A; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. (193 aa) |
| | rsxB | Electron transport complex protein RnfB; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the 4Fe4S bacterial-type ferredoxin family. RnfB subfamily. (190 aa) |
| | rsxD | Ion-translocating oxidoreductase complex subunit D; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the NqrB/RnfD family. (346 aa) |
| | rsxG | Electron transport complex protein RnfG; Part of a membrane-bound complex that couples electron transfer with translocation of ions across the membrane. Belongs to the RnfG family. (211 aa) |
| | pdxH | Pyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (216 aa) |
| | grxD | Putative monothiol glutaredoxin GrlA; COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily. (115 aa) |
| | btuE | Glutathione peroxidase; COG4138 ABC-type cobalamin transport system, ATPase component; vitamin B12 ABC transporter ATP-binding protein; Belongs to the glutathione peroxidase family. (181 aa) |
| | pntB2 | NAD(P) transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. (462 aa) |
| | pntA2 | NAD(P) transhydrogenase alpha subunit; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the AlaDH/PNT family. (510 aa) |
| | hemA | glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (420 aa) |
| | tpx | Thiol peroxidase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Tpx subfamily. (168 aa) |
| | fabI | Enoyl-[acyl-carrier-protein] reductase [NADH]; COG0583 Transcriptional regulator; Hydrogen peroxide-inducible genes activator. (262 aa) |
| | zwf | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (491 aa) |
| | putA | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1315 aa) |
| | grxB | Glutaredoxin 2; Potential frameshift: common BLAST hit: gi|291617008|ref|YP_003519750.1| YceB; predicted lipoprotein. (215 aa) |
| | yecM | yecM; COG3102 Uncharacterized protein conserved in bacteria. (186 aa) |
| | lpdA | COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (476 aa) |
| | aceE | Pyruvate dehydrogenase subunit E1; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (888 aa) |
| | argC | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (334 aa) |
| | AHF74328.1 | Putative peroxiredoxin/glutaredoxin family protein; COG0678 Peroxiredoxin. (244 aa) |
| | sthA | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (465 aa) |
| | yeiB | Putative inner membrane protein; COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain; DNA-binding transcriptional regulator BasR. (387 aa) |
| | yeiQ | D-mannonate oxidoreductase; Potential frameshift: common BLAST hit: gi|271500900|ref|YP_003333925.1| elongation factor P-like protein YeiP; elongation factor P-like protein YeiP. (489 aa) |
| | nrdB | COG0208 Ribonucleotide reductase, beta subunit. (376 aa) |
| | nrdA | Ribonucleotide reductase of class Ia (aerobic) alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (760 aa) |
| | nuoN | NADH:ubiquinone oxidoreductase subunit N; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family. (485 aa) |
| | nuoM | COG1008 NADH:ubiquinone oxidoreductase subunit 4 (chain M). (510 aa) |
| | nuoL | COG1009 NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit. (614 aa) |
| | nuoK | NADH:ubiquinone oxidoreductase subunit K; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 4L family. (100 aa) |
| | nuoJ | NADH:ubiquinone oxidoreductase subunit J; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (187 aa) |
| | nuoI | NADH dehydrogenase subunit I; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (180 aa) |
| | nuoH | NADH:ubiquinone oxidoreductase subunit H; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone. (325 aa) |
| | nuoG | NADH dehydrogenase subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family. (909 aa) |
| | nuoF | NADH dehydrogenase I subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family. (449 aa) |
| | nuoE | COG1905 NADH:ubiquinone oxidoreductase 24 kD subunit. (176 aa) |
| | nuoC | Bifunctional NADH:ubiquinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family. (599 aa) |
| | nuoB | NADH dehydrogenase subunit B; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. (224 aa) |
| | nuoA | NADH:ubiquinone oxidoreductase subunit A; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 3 family. (145 aa) |
| | yfcH | Putative sugar nucleotide epimerase; COG0625 Glutathione S-transferase; Glutathione S-transferase. (300 aa) |
| | pdxB | Erythronate-4-phosphate dehydrogenase; Catalyzes the oxidation of erythronate-4-phosphate to 3- hydroxy-2-oxo-4-phosphonooxybutanoate. (375 aa) |
| | ccmG | Cytochrome c-type biogenesis protein CcmG/DsbE thiol:disulfide oxidoreductase; COG0526 Thiol-disulfide isomerase and thioredoxins. (184 aa) |
| | hemF | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (303 aa) |
| | yffB | Glutathione-dependent thiol reductase; COG1393 Arsenate reductase and related proteins, glutaredoxin family; Belongs to the ArsC family. (127 aa) |
| | bcp | Thioredoxin-dependent thiol peroxidase; COG1225 Peroxiredoxin. (155 aa) |
| | SOPEG_3033 | 3-oxoacyl-[acyl-carrier protein] reductase; Potential frameshift: common BLAST hit: gi|85059716|ref|YP_455418.1| putative magnesium transport protein; putative magnesium transport protein. (248 aa) |
| | guaB | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa) |
| | mqo | Malate:quinone oxidoreductase; COG0579 Predicted dehydrogenase. (539 aa) |
| | ispG | 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (373 aa) |
| | SOPEG_3154 | Short-chain dehydrogenase/reductase SDR; COG0477 Permeases of the major facilitator superfamily; metabolite transport protein. (286 aa) |
| | arnA | Bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase; Bifunctional enzyme that catalyzes the oxidative decarboxylation of UDP-glucuronic acid (UDP-GlcUA) to UDP-4-keto- arabinose (UDP-Ara4O) and the addition of a formyl group to UDP-4- amino-4-deoxy-L-arabinose (UDP-L-Ara4N) to form UDP-L-4-formamido- arabinose (UDP-L-Ara4FN). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides; In the N-terminal section; belongs to the Fmt family. UDP- L-Ara4N formyltransferase subfamily. (660 aa) |
| | nadB | L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (533 aa) |
| | AHF74646.1 | Saccharopine dehydrogenase related protein; COG0702 Predicted nucleoside-diphosphate-sugar epimerases. (213 aa) |
| | dsbA | COG0526 Thiol-disulfide isomerase and thioredoxins. (207 aa) |
| | dxr | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). (413 aa) |
| | tas | COG0667 Predicted oxidoreductases (related to aryl-alcohol dehydrogenases). (346 aa) |
| | AHF74765.1 | COG0604 NADPH:quinone reductase and related Zn-dependent oxidoreductases. (339 aa) |
| | AHF74778.1 | COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases. (328 aa) |
| | gdhA | COG0334 Glutamate dehydrogenase/leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (423 aa) |
| | murB | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (345 aa) |
| | hemG | 16S ribosomal RNA; ISSoEn2, terminal inverted repeat. (179 aa) |
| | fre | NAD(P)H-flavin reductase; COG0006 Xaa-Pro aminopeptidase; proline dipeptidase. (233 aa) |
| | SOPEG_3675 | Oxidoreductase; ISSoEn2, terminal inverted repeat. (255 aa) |
| | dusB | tRNA-dihydrouridine synthase B; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. (321 aa) |
| | msrQ | Putative sulfite oxidase subunit YedZ; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subuni [...] (199 aa) |
| | cybC | Soluble cytochrome b562; COG0312 Predicted Zn-dependent proteases and their inactivated homologs; TldE/PmbA protein part of proposed TldE/TldD proteolytic complex. (128 aa) |
| | AHF74896.1 | 2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (302 aa) |
| | gldA | COG0371 Glycerol dehydrogenase and related enzymes. (366 aa) |
| | arsC | COG1393 Arsenate reductase and related proteins, glutaredoxin family. (120 aa) |
| | yqgE | yqgE; COG1678 Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (187 aa) |
| | serA | COG0111 Phosphoglycerate dehydrogenase and related dehydrogenases; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (410 aa) |
| | ubiH | Ubiquinone biosynthesis monooxygenase UbiH/COQ6, 2-octaprenyl-6-methoxyphenol hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (392 aa) |
| | visC | 2-octaprenyl-3-methyl-6-methoxy-1 4-benzoquinol hydroxylase; COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. (405 aa) |
| | fldB | Flavodoxin; Low-potential electron donor to a number of redox enzymes. Belongs to the flavodoxin family. (172 aa) |
| | dsbC | Thiol:disulfide interchange protein DsbC; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. (238 aa) |
| | uxaB2 | COG2721 Altronate dehydratase; D-altronate dehydratase. (483 aa) |
| | folD | tRNA-Arg; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (290 aa) |
| | icd | COG2838 Monomeric isocitrate dehydrogenase; Belongs to the monomeric-type IDH family. (744 aa) |
| | ybbO | Putative NAD(P)-dependent oxidoreductase EC-YbbO; COG2755 Lysophospholipase L1 and related esterases; Lysophospholipase; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (258 aa) |
| | cyoC | COG0843 Heme/copper-type cytochrome/quinol oxidases, subunit 1; Cytochrome O ubiquinol oxidase subunit I. (204 aa) |
| | cyoD | COG3125 Heme/copper-type cytochrome/quinol oxidase, subunit 4. (110 aa) |
| | ribD | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (375 aa) |
| | AHF75074.1 | DoxX family protein; COG2259 Predicted membrane protein. (140 aa) |
| | gor | Glutathione reductase; COG1249 Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes. (450 aa) |
| | mtlD | Mannitol-1-phosphate 5-dehydrogenase; Potential frameshift: common BLAST hit: gi|85057992|ref|YP_453694.1| PTS system mannitol-specific IIABC component; COG4668 Mannitol/fructose-specific phosphotransferase system, IIA domain; PTS system mannitol-specific transporter subunit IICBA. (382 aa) |
| | sodA | Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (205 aa) |
