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prmA prmA HH_0827 HH_0827 amiA amiA tyrS tyrS spoT spoT HH_0834 HH_0834 HH_0835 HH_0835 HH_0836 HH_0836 HH_0837 HH_0837 rimP rimP rbfA rbfA tgt tgt proC proC ppx ppx queA queA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prmARibosomal protein L11 methyltransferase; Methylates ribosomal protein L11; Belongs to the methyltransferase superfamily. PrmA family. (317 aa)
HH_0827Hypothetical protein; Predicted membrane-associated. (284 aa)
amiAN-acetylmuramoyl-L-alanine amidase. (388 aa)
tyrStyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (400 aa)
spoTConserved hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. (716 aa)
HH_0834Predicted secreted protein. (168 aa)
HH_0835Predicted secreted protein. (129 aa)
HH_0836Conserved hypothetical protein; Similar to Campylobacter jejuni CJ1249. (475 aa)
HH_0837Conserved hypothetical protein; Similar to Helicobacter pylori HP1504; Belongs to the methyltransferase superfamily. (250 aa)
rimPConserved hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (157 aa)
rbfARibosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (116 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form th [...] (381 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (284 aa)
ppxExopolyphosphatase. (490 aa)
queAS-adenosylmethionine:tRNA-ribosyltransferase- isomerase (queuine synthetase); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (365 aa)
Your Current Organism:
Helicobacter hepaticus
NCBI taxonomy Id: 235279
Other names: H. hepaticus ATCC 51449, Helicobacter hepaticus ATCC 51449, Helicobacter hepaticus str. ATCC 51449
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