STRINGSTRING
GK1375 GK1375 GK1403 GK1403 tatA tatA yidC yidC GK2431 GK2431 comGB comGB secDF secDF GK2586 GK2586 GK2621 GK2621 GK2627 GK2627 GK2633 GK2633 GK2634 GK2634 tig tig GK3046 GK3046 secA1 secA1 GK3144 GK3144 secA2 secA2 GK3175 GK3175 GK3256 GK3256 GK3257 GK3257 GK3258 GK3258 GK3259 GK3259 GK3260 GK3260 GK3435 GK3435 yidC-2 yidC-2 fliH fliH GK1207 GK1207 ffh ffh ftsY ftsY GK0815 GK0815 GK0811 GK0811 prsA prsA tatC tatC GK0243 GK0243 secY secY secE secE fliI fliI fliJ fliJ fliP fliP fliQ fliQ fliR fliR flhB flhB flhA flhA flhF flhF GK1279 GK1279
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GK1375Hypothetical protein. (435 aa)
GK1403Hypothetical conserved protein. (553 aa)
tatAHypothetical conserved protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. (56 aa)
yidCStage III sporulation protein J; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. (249 aa)
GK2431Hypothetical conserved protein. (108 aa)
comGBDNA transport machinery. (338 aa)
secDFPreprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (750 aa)
GK2586Hypothetical conserved protein. (90 aa)
GK2621Hypothetical protein. (153 aa)
GK2627Hypothetical conserved protein. (403 aa)
GK2633Hypothetical protein. (210 aa)
GK2634Hypothetical protein. (189 aa)
tigTrigger factor (prolyl isomerase); Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. (428 aa)
GK3046Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (78 aa)
secA1Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. (837 aa)
GK3144Flagellar biosynthesis. (98 aa)
secA2Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (797 aa)
GK3175Hypothetical protein. (652 aa)
GK3256Hypothetical protein. (79 aa)
GK3257Hypothetical conserved protein. (236 aa)
GK3258Hypothetical conserved protein. (390 aa)
GK3259Hypothetical protein. (731 aa)
GK3260Hypothetical protein. (438 aa)
GK3435Hypothetical protein. (585 aa)
yidC-2Stage III sporulation protein J; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. (254 aa)
fliHFlagellar assembly protein. (256 aa)
GK1207Hypothetical conserved protein. (95 aa)
ffhSignal recognition particle GTPase; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (446 aa)
ftsYSignal recognition particle GTPase (docking protein); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (328 aa)
GK0815Oligopeptide ABC transporter (ATP-binding protein); Belongs to the ABC transporter superfamily. (311 aa)
GK0811Oligopeptide ABC transporter (oligopeptide-binding protein). (528 aa)
prsAPost-translocation molecular chaperone; Plays a major role in protein secretion by helping the post- translocational extracellular folding of several secreted proteins. (281 aa)
tatCHypothetical conserved protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. (247 aa)
GK0243Hypothetical conserved protein. (50 aa)
secYPreprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (430 aa)
secEPreprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (61 aa)
fliIFlagellar-specific ATP synthase. (422 aa)
fliJFlagellar basal body formation protein. (148 aa)
fliPFlagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. (222 aa)
fliQFlagellar protein required for flagellar formation; Role in flagellar biosynthesis. Belongs to the FliQ/MopD/SpaQ family. (89 aa)
fliRFlagellar biosynthetic protein; Role in flagellar biosynthesis. Belongs to the FliR/MopE/SpaR family. (257 aa)
flhBFlagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. (360 aa)
flhAFlagellar biosynthetic protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. (681 aa)
flhFFlagellar biosynthetic protein (flagellar GTP-binding protein). (409 aa)
GK1279Hypothetical conserved protein. (246 aa)
Your Current Organism:
Geobacillus kaustophilus
NCBI taxonomy Id: 235909
Other names: G. kaustophilus HTA426, Geobacillus kaustophilus HTA426
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.