node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GK0243 | secDF | GK0243 | GK2582 | Hypothetical conserved protein. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.571 |
GK0243 | tatA | GK0243 | GK1515 | Hypothetical conserved protein. | Hypothetical conserved protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.904 |
GK0243 | tatC | GK0243 | GK0244 | Hypothetical conserved protein. | Hypothetical conserved protein; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. | 0.988 |
GK3046 | secA1 | GK3046 | GK3107 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | 0.829 |
GK3046 | secA2 | GK3046 | GK3170 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.829 |
GK3046 | secDF | GK3046 | GK2582 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.969 |
GK3046 | secE | GK3046 | GK0091 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.979 |
GK3046 | secY | GK3046 | GK0126 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.947 |
GK3046 | yidC | GK3046 | GK1822 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Stage III sporulation protein J; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.810 |
GK3046 | yidC-2 | GK3046 | GK3496 | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Stage III sporulation protein J; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins; Belongs to the OXA1/ALB3/YidC family. Type 2 subfamily. | 0.810 |
flhA | flhB | GK1238 | GK1237 | Flagellar biosynthetic protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. | 0.998 |
flhA | fliP | GK1238 | GK1234 | Flagellar biosynthetic protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | Flagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. | 0.990 |
flhB | flhA | GK1237 | GK1238 | Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. | Flagellar biosynthetic protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | 0.998 |
flhB | fliP | GK1237 | GK1234 | Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. | Flagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. | 0.998 |
fliP | flhA | GK1234 | GK1238 | Flagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. | Flagellar biosynthetic protein; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family. | 0.990 |
fliP | flhB | GK1234 | GK1237 | Flagellar biosynthetic protein; Plays a role in the flagellum-specific transport system. Belongs to the FliP/MopC/SpaP family. | Flagellar biosynthetic protein; Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the type III secretion exporter family. | 0.998 |
secA1 | GK3046 | GK3107 | GK3046 | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Protein translocation subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.829 |
secA1 | secA2 | GK3107 | GK3170 | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.904 |
secA1 | secDF | GK3107 | GK2582 | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Preprotein translocase subunits D and F; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. | 0.639 |
secA1 | secE | GK3107 | GK0091 | Preprotein translocase subunit (ATPase, RNA helicase); Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane; Belongs to the SecA family. | Preprotein translocase subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.809 |