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BKCO1_4300032 BKCO1_4300032 BKCO1_4400085 BKCO1_4400085 BKCO1_4100064 BKCO1_4100064 BKCO1_32000108 BKCO1_32000108 BKCO1_310004 BKCO1_310004 BKCO1_2300080 BKCO1_2300080 BKCO1_2400072 BKCO1_2400072 BKCO1_18000121 BKCO1_18000121 BKCO1_24000114 BKCO1_24000114 BKCO1_17000108 BKCO1_17000108 BKCO1_1600068 BKCO1_1600068 uba4 uba4 BKCO1_2000012 BKCO1_2000012 BKCO1_2000098 BKCO1_2000098 BKCO1_1300048 BKCO1_1300048 BKCO1_17000112 BKCO1_17000112 CLP1 CLP1 BKCO1_18000149 BKCO1_18000149 BKCO1_15000142 BKCO1_15000142 BKCO1_15000157 BKCO1_15000157 BKCO1_900037 BKCO1_900037 BKCO1_1300028 BKCO1_1300028 BKCO1_13000107 BKCO1_13000107 BKCO1_13000118 BKCO1_13000118 BKCO1_1000024 BKCO1_1000024 BKCO1_1000019 BKCO1_1000019 BKCO1_6000129 BKCO1_6000129 BKCO1_7000154 BKCO1_7000154 BKCO1_6000117 BKCO1_6000117 BKCO1_5700011 BKCO1_5700011 BKCO1_400058 BKCO1_400058 BKCO1_4000211 BKCO1_4000211 BKCO1_30002 BKCO1_30002 URM1 URM1 BKCO1_600047 BKCO1_600047 BKCO1_3200029 BKCO1_3200029 BKCO1_3800032 BKCO1_3800032 BKCO1_32000113 BKCO1_32000113 BKCO1_2900022 BKCO1_2900022 BKCO1_31000113 BKCO1_31000113 BKCO1_3100097 BKCO1_3100097 BKCO1_2100032 BKCO1_2100032 BKCO1_21000135 BKCO1_21000135 BKCO1_1800045 BKCO1_1800045 BKCO1_2200040 BKCO1_2200040 BKCO1_18000143 BKCO1_18000143 BKCO1_15000146 BKCO1_15000146 BKCO1_1500065 BKCO1_1500065 BKCO1_1500079 BKCO1_1500079 BKCO1_14000168 BKCO1_14000168 BKCO1_13000102 BKCO1_13000102 BKCO1_1100074 BKCO1_1100074 BKCO1_3000123 BKCO1_3000123 BKCO1_8000130 BKCO1_8000130 BKCO1_8000185 BKCO1_8000185 BKCO1_60001 BKCO1_60001 BKCO1_600016 BKCO1_600016 TRM8 TRM8 BKCO1_6000231 BKCO1_6000231 BKCO1_500094 BKCO1_500094 BKCO1_400027 BKCO1_400027 BKCO1_3000139 BKCO1_3000139 BKCO1_3000148 BKCO1_3000148 BKCO1_200059 BKCO1_200059 BKCO1_2000238 BKCO1_2000238 BKCO1_1000659 BKCO1_1000659 BKCO1_1000236 BKCO1_1000236 BKCO1_1000443 BKCO1_1000443 BKCO1_1000364 BKCO1_1000364 BKCO1_2000294 BKCO1_2000294 BKCO1_3900046 BKCO1_3900046 BKCO1_1000198 BKCO1_1000198 NCS6 NCS6 BKCO1_3200036 BKCO1_3200036 BKCO1_1000196 BKCO1_1000196 BKCO1_770003 BKCO1_770003 BKCO1_2800081 BKCO1_2800081 BKCO1_11600010 BKCO1_11600010 BKCO1_7100029 BKCO1_7100029 BKCO1_990002 BKCO1_990002 BKCO1_9200024 BKCO1_9200024 LSM3 LSM3 AIM41 AIM41 NAT10 NAT10 LSM4 LSM4 BKCO1_650003 BKCO1_650003 BKCO1_5800027 BKCO1_5800027 BKCO1_5400050 BKCO1_5400050 BKCO1_5300044 BKCO1_5300044 BKCO1_5600029 BKCO1_5600029 BKCO1_5100020 BKCO1_5100020 BKCO1_4500012 BKCO1_4500012 BKCO1_520008 BKCO1_520008 BKCO1_12000187 BKCO1_12000187 KAE1 KAE1 BKCO1_11000137 BKCO1_11000137 BKCO1_4600090 BKCO1_4600090 BKCO1_10000157 BKCO1_10000157 LSM5 LSM5 BKCO1_340002 BKCO1_340002 TRM5 TRM5 ALA1 ALA1 BKCO1_8300010 BKCO1_8300010 BKCO1_7200035 BKCO1_7200035 BKCO1_7000020 BKCO1_7000020 BKCO1_6700028 BKCO1_6700028 BKCO1_7100011 BKCO1_7100011 BKCO1_7000032 BKCO1_7000032 BKCO1_5200034 BKCO1_5200034 TRM82 TRM82 BKCO1_5200010 BKCO1_5200010 NCS2 NCS2 BKCO1_450009 BKCO1_450009 BKCO1_5600013 BKCO1_5600013 BKCO1_450003 BKCO1_450003 BKCO1_4400040 BKCO1_4400040 BKCO1_4100088 BKCO1_4100088
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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BKCO1_4300032Mitochondrial gtpase. (620 aa)
BKCO1_4400085Trna (Uracil-5-)-methyltransferase trm9. (239 aa)
BKCO1_4100064DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family. (121 aa)
BKCO1_32000108Chromatin associated protein kti12. (298 aa)
BKCO1_310004Diphthamide biosynthesis protein 3. (82 aa)
BKCO1_2300080Rna-binding la domain protein. (443 aa)
BKCO1_2400072Protein phosphatase 2c. (583 aa)
BKCO1_18000121Rnase p rpr2 rpp21 subunit domain-containing protein. (166 aa)
BKCO1_24000114tRNA dimethylallyltransferase. (578 aa)
BKCO1_17000108tRNA(His) guanylyltransferase; Adds a GMP to the 5'-end of tRNA(His) after transcription and RNase P cleavage. (313 aa)
BKCO1_1600068Ribonuclease p complex subunit pop1. (849 aa)
uba4Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and MOCS2A. Its N-terminus first activates urm1 and MOCS2A as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and MOCS2A to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] (616 aa)
BKCO1_2000012Flavodoxin and radical sam domain protein. (796 aa)
BKCO1_2000098Trna-dihydrouridine synthase 1. (623 aa)
BKCO1_1300048ThiF domain-containing protein. (505 aa)
BKCO1_170001123-hydroxyacyl-dehydrogenase type-2. (263 aa)
CLP1mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation. (504 aa)
BKCO1_18000149Trna (Uracil-o-)-methyltransferase. (629 aa)
BKCO1_15000142Thiosulfate sulfurtransferase. (343 aa)
BKCO1_15000157tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. (495 aa)
BKCO1_900037Trna (Adenine-n-)-methyltransferase. (440 aa)
BKCO1_1300028Methionyl-trna formyltransferase. (353 aa)
BKCO1_13000107Trna pseudouridine synthase. (678 aa)
BKCO1_13000118Rna-processing protein. (261 aa)
BKCO1_1000024Alkylated dna repair protein. (367 aa)
BKCO1_1000019Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase; Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs. (403 aa)
BKCO1_6000129Queuosine salvage protein; Involved in salvaging queuosine. (365 aa)
BKCO1_7000154Ribonuclease p mrp subunit pop7 protein. (187 aa)
BKCO1_6000117Trna splicing endonuclease subunit. (440 aa)
BKCO1_5700011Putative methyltransferase tarbp1-like. (1259 aa)
BKCO1_400058Pp-loop family protein. (732 aa)
BKCO1_4000211Uncharacterized protein. (332 aa)
BKCO1_30002Thioredoxin-like protein. (209 aa)
URM1Ubiquitin-related modifier 1; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2-thiolation reaction by being thiocarboxylated (-COSH) at its C-terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target pr [...] (109 aa)
BKCO1_600047Rna methylase family protein. (473 aa)
BKCO1_3200029Cysteine desulfurase. (508 aa)
BKCO1_3800032Trna dihydrouridine synthase. (403 aa)
BKCO1_32000113Rna polymerase ii elongator. (962 aa)
BKCO1_2900022Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. (1302 aa)
BKCO1_31000113Trna methyltransferase complex gcd14 subunit. (511 aa)
BKCO1_3100097tRNA-splicing endonuclease subunit Sen2; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structural [...] (435 aa)
BKCO1_2100032Thump domain-containing protein. (274 aa)
BKCO1_21000135Glutamyl-trna synthetase. (216 aa)
BKCO1_1800045Trna wybutosine-synthesizing protein. (309 aa)
BKCO1_2200040Pseudouridylate synthase 3. (645 aa)
BKCO1_18000143C-5 cytosine methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (645 aa)
BKCO1_15000146Exportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1019 aa)
BKCO1_1500065tRNA-dihydrouridine(47) synthase [NAD(P)(+)]; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Specifically modifies U47 in cytoplasmic tRNAs. (770 aa)
BKCO1_1500079Lysyl-trna synthetase. (568 aa)
BKCO1_14000168Uncharacterized protein. (857 aa)
BKCO1_13000102Heat repeat protein. (1834 aa)
BKCO1_1100074Histone acetylation protein 2. (351 aa)
BKCO1_3000123Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (582 aa)
BKCO1_8000130Uncharacterized protein. (179 aa)
BKCO1_8000185Translation initiation protein sua5. (563 aa)
BKCO1_60001Release factor h-coupled family protein. (637 aa)
BKCO1_600016Ribonuclease p 40kda subunit. (354 aa)
TRM8tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (285 aa)
BKCO1_6000231Trna methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (575 aa)
BKCO1_500094Trna m g methyltransferase domain containing protein. (447 aa)
BKCO1_400027tRNA ligase. (815 aa)
BKCO1_3000139Trna a64-2-o-ribosylphosphate transferase. (770 aa)
BKCO1_3000148Uncharacterized protein. (251 aa)
BKCO1_200059Uncharacterized protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Trm1 family. (700 aa)
BKCO1_2000238Alpha-tubulin suppressor protein aats1. (372 aa)
BKCO1_1000659Oxidoreductase domain containing protein. (432 aa)
BKCO1_1000236Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Belongs to the eukaryotic/archaeal RNase P protein component 2 family. (189 aa)
BKCO1_1000443Trna wybutosine-synthesizing protein 2. (589 aa)
BKCO1_1000364Alanyl-trna synthetase. (281 aa)
BKCO1_2000294Trna specific adenosine deaminase. (192 aa)
BKCO1_3900046NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (305 aa)
BKCO1_1000198Paxneb protein. (410 aa)
NCS6Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (1079 aa)
BKCO1_3200036Serine threonine-protein kinase bud32. (337 aa)
BKCO1_1000196Trna-splicing endonuclease subunit sen34. (576 aa)
BKCO1_770003Rna polymerase ii accessory cdc73. (592 aa)
BKCO1_2800081Wd repeat protein. (1201 aa)
BKCO1_11600010Barwin-like endoglucanase. (277 aa)
BKCO1_7100029Ribonuclease p complex subunit pop2. (313 aa)
BKCO1_990002Short chain dehydrogenase. (292 aa)
BKCO1_9200024Trna-splicing endonuclease subunit sen-15 protein. (190 aa)
LSM3U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (99 aa)
AIM41Altered inheritance of mitochondria protein 41. (190 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein TAN1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1075 aa)
LSM4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (112 aa)
BKCO1_650003Pseudouridine synthase. (751 aa)
BKCO1_5800027Pseudouridine synthase. (429 aa)
BKCO1_5400050Exonuclease. (738 aa)
BKCO1_5300044Dextranase. (624 aa)
BKCO1_5600029Ribonuclease z. (1076 aa)
BKCO1_5100020Pseudouridine synthase. (501 aa)
BKCO1_4500012S-adenosyl-l-methionine-dependent methyltransferase. (295 aa)
BKCO1_520008Lsm domain-containing protein. (80 aa)
BKCO1_12000187Methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (890 aa)
KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (353 aa)
BKCO1_11000137Leucine carboxyl methyltransferase 2. (1034 aa)
BKCO1_4600090Trna uridine 5-carboxymethylaminomethyl modification enzyme gida. (733 aa)
BKCO1_10000157Protein cgi121; Belongs to the CGI121/TPRKB family. (217 aa)
LSM5U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (83 aa)
BKCO1_340002Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. (477 aa)
TRM5tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. (483 aa)
ALA1Alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. Belongs to the class-II aminoacyl-tRNA synthetase family. (964 aa)
BKCO1_8300010Cytochrome b5. (476 aa)
BKCO1_7200035Queuine tRNA-ribosyltransferase catalytic subunit 1; Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, formi [...] (404 aa)
BKCO1_7000020Ribonuclease P protein subunit. (247 aa)
BKCO1_6700028Eukaryotic translation initiation factor gamma subunit. (625 aa)
BKCO1_7100011Mrna cleavage and polyadenylation specificity factor complex subunit. (737 aa)
BKCO1_7000032Phosphotransferase-like. (551 aa)
BKCO1_5200034Actin binding protein. (441 aa)
TRM82tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (482 aa)
BKCO1_5200010Trm112p-domain-containing protein. (138 aa)
NCS2Cytoplasmic tRNA 2-thiolation protein 2; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. (430 aa)
BKCO1_450009Riboflavin aldehyde-forming enzyme. (220 aa)
BKCO1_5600013Small nuclear ribonucleoprotein. (127 aa)
BKCO1_450003Geranylgeranyl pyrophosphate synthetase. (461 aa)
BKCO1_4400040Galactosyl transferase. (419 aa)
BKCO1_4100088Trna-specific adenosine deaminase. (404 aa)
Your Current Organism:
Diplodia corticola
NCBI taxonomy Id: 236234
Other names: Botryosphaeria corticola, Botryosphaeria corticola A.J.L.Phillips, A.Alves & J. Luque 2004, CBS 112549, D. corticola, Diplodia corticola A.J.L. Phillips, A. Alves & J. Luque 2004
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