22 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ESP1	Separase. (1598 aa)
	REC8	Rad21_Rec8_N domain-containing protein. (635 aa)
	CaO19.5053	Uncharacterized protein. (260 aa)
	IRR1	Irr1p. (1089 aa)
	PDS5	Pds5p. (1303 aa)
	YCS4	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. (1172 aa)
	SMC2	Structural maintenance of chromosomes protein. (1171 aa)
	CaO19.1384	Uncharacterized protein. (647 aa)
	YCG1	Condensin subunit. (1259 aa)
	SMC3	Structural maintenance of chromosomes protein. (1237 aa)
	MMS21	SUMO ligase. (272 aa)
	CaO19.6189	Chalcone_isomerase domain-containing protein. (237 aa)
	CaO19.4161	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids. (371 aa)
	CaO19.2673	Smc5-Smc6 complex subunit. (339 aa)
	BRN1	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (744 aa)
	CaO19.3080	Sister chromatid cohesion protein. (1046 aa)
	CaO19.3965	Uncharacterized protein. (216 aa)
	SMC1	Structural maintenance of chromosomes protein. (1240 aa)
	MCD1	Kleisin alpha. (564 aa)
	SMC5	DNA repair ATPase. (1073 aa)
	SMC4	Structural maintenance of chromosomes protein. (1368 aa)
	SMC6	DNA repair protein. (1128 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BRN1	ESP1	A0A1D8PMC8	A0A1D8PCM0	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Separase.	0.660
BRN1	MCD1	A0A1D8PMC8	A0A1D8PU88	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Kleisin alpha.	0.699
BRN1	SMC1	A0A1D8PMC8	A0A1D8PSI8	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Structural maintenance of chromosomes protein.	0.841
BRN1	SMC2	A0A1D8PMC8	A0A1D8PI59	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Structural maintenance of chromosomes protein.	0.999
BRN1	SMC3	A0A1D8PMC8	A0A1D8PJK7	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Structural maintenance of chromosomes protein.	0.871
BRN1	SMC4	A0A1D8PMC8	Q5A4Y2	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Structural maintenance of chromosomes protein.	0.999
BRN1	SMC5	A0A1D8PMC8	Q59UE8	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	DNA repair ATPase.	0.934
BRN1	SMC6	A0A1D8PMC8	Q5AGX1	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	DNA repair protein.	0.787
BRN1	YCG1	A0A1D8PMC8	A0A1D8PJE8	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Condensin subunit.	0.999
BRN1	YCS4	A0A1D8PMC8	A0A1D8PI01	Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes.	Condensin complex subunit 1; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.	0.999
CaO19.1384	CaO19.3965	A0A1D8PIK1	A0A1D8PP17	Uncharacterized protein.	Uncharacterized protein.	0.912
CaO19.1384	CaO19.4161	A0A1D8PIK1	A0A1D8PL51	Uncharacterized protein.	Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.	0.911
CaO19.1384	MMS21	A0A1D8PIK1	A0A1D8PKF6	Uncharacterized protein.	SUMO ligase.	0.897
CaO19.1384	SMC1	A0A1D8PIK1	A0A1D8PSI8	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.491
CaO19.1384	SMC2	A0A1D8PIK1	A0A1D8PI59	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.458
CaO19.1384	SMC3	A0A1D8PIK1	A0A1D8PJK7	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.527
CaO19.1384	SMC4	A0A1D8PIK1	Q5A4Y2	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.508
CaO19.1384	SMC5	A0A1D8PIK1	Q59UE8	Uncharacterized protein.	DNA repair ATPase.	0.899
CaO19.1384	SMC6	A0A1D8PIK1	Q5AGX1	Uncharacterized protein.	DNA repair protein.	0.901
CaO19.2673	CaO19.3965	A0A1D8PLR6	A0A1D8PP17	Smc5-Smc6 complex subunit.	Uncharacterized protein.	0.999