STRINGSTRING
CaO19.4748 CaO19.4748 CaO19.6356 CaO19.6356 CaO19.1548 CaO19.1548 A0A1D8PH20 A0A1D8PH20 SNU114 SNU114 CaO19.6866 CaO19.6866 SMD2 SMD2 CaO19.82 CaO19.82 CaO19.2261 CaO19.2261 CaO19.6989 CaO19.6989 CaO19.7375 CaO19.7375 CaO19.4659 CaO19.4659 CaO19.3098 CaO19.3098 CaO19.3178 CaO19.3178 CaO19.4326 CaO19.4326 A0A1D8PNM3 A0A1D8PNM3 A0A1D8PPC8 A0A1D8PPC8 CaO19.2378 CaO19.2378 CaO19.2621 CaO19.2621 CaO19.7343 CaO19.7343 CaO19.7581 CaO19.7581 CaO19.7673 CaO19.7673 SMD3 SMD3 YHC1 YHC1 IRC6 IRC6 PRP28 PRP28 CaO19.1394 CaO19.1394 CaO19.2230 CaO19.2230 CaO19.1975 CaO19.1975 PRP8 PRP8 RSE1 RSE1 PRP5 PRP5 CaO19.2675 CaO19.2675 PRP3 PRP3 SNU13 SNU13 CaO19.4724 CaO19.4724
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.4748U2 snRNP complex subunit. (131 aa)
CaO19.6356U4/U6-U5 snRNP complex subunit. (911 aa)
CaO19.1548U4/U6-U5 snRNP complex subunit. (242 aa)
A0A1D8PH20Small nuclear ribonucleoprotein G. (74 aa)
SNU114U5 snRNP GTPase. (1022 aa)
CaO19.6866U1 snRNP complex subunit. (347 aa)
SMD2Small nuclear ribonucleoprotein Sm D2. (112 aa)
CaO19.82U4/U6-U5 snRNP complex subunit. (569 aa)
CaO19.2261U2 snRNP complex subunit. (259 aa)
CaO19.6989RRM domain-containing protein. (107 aa)
CaO19.7375Uncharacterized protein. (204 aa)
CaO19.4659Uncharacterized protein. (425 aa)
CaO19.3098ATP-dependent RNA helicase. (1987 aa)
CaO19.3178SF3a splicing factor complex subunit. (513 aa)
CaO19.4326U4/U6-U5 snRNP complex subunit. (673 aa)
A0A1D8PNM3mRNA splicing protein. (127 aa)
A0A1D8PPC8Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (86 aa)
CaO19.2378Uncharacterized protein. (117 aa)
CaO19.2621mRNA splicing protein. (125 aa)
CaO19.7343U4/U6-U5 snRNP complex subunit. (458 aa)
CaO19.7581U2 snRNP complex subunit. (471 aa)
CaO19.7673Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (116 aa)
SMD3Small nuclear ribonucleoprotein Sm D3. (106 aa)
YHC1U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (150 aa)
IRC6Increased recombination centers protein 6; Involved in gross chromosomal rearrangements (GCRs) and telomere healing. (275 aa)
PRP28Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (581 aa)
CaO19.1394Uncharacterized protein. (166 aa)
CaO19.2230U2 snRNP complex subunit. (119 aa)
CaO19.1975Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (148 aa)
PRP8U4/U6-U5 snRNP complex subunit. (2416 aa)
RSE1Pre-mRNA-splicing factor RSE1; Involved in pre-mRNA splicing and cell cycle control. (1219 aa)
PRP5Pre-mRNA-processing ATP-dependent RNA helicase PRP5; ATP-dependent RNA helicase involved spliceosome assembly and in nuclear splicing. Catalyzes an ATP-dependent conformational change of U2 snRNP. Bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA (By similarity); Belongs to the DEAD box helicase family. DDX46/PRP5 subfamily. (884 aa)
CaO19.2675mRNA-binding U2 snRNP complex subunit. (1094 aa)
PRP3U4/U6-U5 snRNP complex subunit. (446 aa)
SNU1313 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity). (126 aa)
CaO19.4724U1-type domain-containing protein. (256 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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