STRINGSTRING
CaO19.6356 CaO19.6356 CaO19.1548 CaO19.1548 SNU114 SNU114 CaO19.82 CaO19.82 CaO19.3098 CaO19.3098 CaO19.4326 CaO19.4326 CaO19.7343 CaO19.7343 PRP28 PRP28 CaO19.1975 CaO19.1975 PRP8 PRP8 SNU13 SNU13
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.6356U4/U6-U5 snRNP complex subunit. (911 aa)
CaO19.1548U4/U6-U5 snRNP complex subunit. (242 aa)
SNU114U5 snRNP GTPase. (1022 aa)
CaO19.82U4/U6-U5 snRNP complex subunit. (569 aa)
CaO19.3098ATP-dependent RNA helicase. (1987 aa)
CaO19.4326U4/U6-U5 snRNP complex subunit. (673 aa)
CaO19.7343U4/U6-U5 snRNP complex subunit. (458 aa)
PRP28Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (581 aa)
CaO19.1975Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (148 aa)
PRP8U4/U6-U5 snRNP complex subunit. (2416 aa)
SNU1313 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity). (126 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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