6 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CaO19.6356	U4/U6-U5 snRNP complex subunit. (911 aa)
	SNU114	U5 snRNP GTPase. (1022 aa)
	CaO19.3098	ATP-dependent RNA helicase. (1987 aa)
	PRP28	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity). (581 aa)
	CaO19.1975	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (148 aa)
	PRP8	U4/U6-U5 snRNP complex subunit. (2416 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CaO19.1975	CaO19.3098	Q5A1M0	A0A1D8PMR5	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	ATP-dependent RNA helicase.	0.998
CaO19.1975	CaO19.6356	Q5A1M0	A0A1D8PFI2	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	U4/U6-U5 snRNP complex subunit.	0.999
CaO19.1975	PRP28	Q5A1M0	Q59W52	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	0.994
CaO19.1975	PRP8	Q5A1M0	Q5A322	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	U4/U6-U5 snRNP complex subunit.	0.999
CaO19.1975	SNU114	Q5A1M0	A0A1D8PH71	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	U5 snRNP GTPase.	0.999
CaO19.3098	CaO19.1975	A0A1D8PMR5	Q5A1M0	ATP-dependent RNA helicase.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.998
CaO19.3098	CaO19.6356	A0A1D8PMR5	A0A1D8PFI2	ATP-dependent RNA helicase.	U4/U6-U5 snRNP complex subunit.	0.999
CaO19.3098	PRP28	A0A1D8PMR5	Q59W52	ATP-dependent RNA helicase.	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	0.980
CaO19.3098	PRP8	A0A1D8PMR5	Q5A322	ATP-dependent RNA helicase.	U4/U6-U5 snRNP complex subunit.	0.999
CaO19.3098	SNU114	A0A1D8PMR5	A0A1D8PH71	ATP-dependent RNA helicase.	U5 snRNP GTPase.	0.999
CaO19.6356	CaO19.1975	A0A1D8PFI2	Q5A1M0	U4/U6-U5 snRNP complex subunit.	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.999
CaO19.6356	CaO19.3098	A0A1D8PFI2	A0A1D8PMR5	U4/U6-U5 snRNP complex subunit.	ATP-dependent RNA helicase.	0.999
CaO19.6356	PRP28	A0A1D8PFI2	Q59W52	U4/U6-U5 snRNP complex subunit.	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	0.998
CaO19.6356	PRP8	A0A1D8PFI2	Q5A322	U4/U6-U5 snRNP complex subunit.	U4/U6-U5 snRNP complex subunit.	0.999
CaO19.6356	SNU114	A0A1D8PFI2	A0A1D8PH71	U4/U6-U5 snRNP complex subunit.	U5 snRNP GTPase.	0.999
PRP28	CaO19.1975	Q59W52	Q5A1M0	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family.	0.994
PRP28	CaO19.3098	Q59W52	A0A1D8PMR5	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	ATP-dependent RNA helicase.	0.980
PRP28	CaO19.6356	Q59W52	A0A1D8PFI2	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	U4/U6-U5 snRNP complex subunit.	0.998
PRP28	PRP8	Q59W52	Q5A322	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	U4/U6-U5 snRNP complex subunit.	0.999
PRP28	SNU114	Q59W52	A0A1D8PH71	Pre-mRNA-splicing ATP-dependent RNA helicase PRP28; ATP-dependent RNA helicase involved in mRNA splicing. May destabilize the U1/5'-splice site duplex to permit an effective competition for the 5'-splice site by the U6 snRNA, resulting in the switch between U1 and U6 at the 5'-splice site. May also act to unwind the U4/U6 base-pairing interaction in the U4/U6/U5 snRNP, facilitating the first covalent step of splicing (By similarity).	U5 snRNP GTPase.	0.999