13 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CaO19.366	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family. (336 aa)
	REC8	Rad21_Rec8_N domain-containing protein. (635 aa)
	DLH1	Recombinase; Belongs to the RecA family. (324 aa)
	CaO19.5212	SUMO ligase. (366 aa)
	RAD50	MRX complex DNA-binding subunit. (1332 aa)
	SMC3	Structural maintenance of chromosomes protein. (1237 aa)
	DDC1	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (488 aa)
	RFA1	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (624 aa)
	SMT3	SUMO family protein. (102 aa)
	RAD51	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (361 aa)
	MEC3	Checkpoint protein; Belongs to the HUS1 family. (319 aa)
	MCD1	Kleisin alpha. (564 aa)
	CaO19.2922	TBPIP domain-containing protein. (205 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CaO19.2922	DDC1	A0A1D8PMI3	A0A1D8PJM0	TBPIP domain-containing protein.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.539
CaO19.2922	DLH1	A0A1D8PMI3	A0A1D8PFE4	TBPIP domain-containing protein.	Recombinase; Belongs to the RecA family.	0.699
CaO19.2922	MCD1	A0A1D8PMI3	A0A1D8PU88	TBPIP domain-containing protein.	Kleisin alpha.	0.554
CaO19.2922	RAD51	A0A1D8PMI3	Q59UY8	TBPIP domain-containing protein.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.616
CaO19.366	DDC1	A0A1D8PKX2	A0A1D8PJM0	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	0.999
CaO19.366	DLH1	A0A1D8PKX2	A0A1D8PFE4	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	Recombinase; Belongs to the RecA family.	0.524
CaO19.366	MEC3	A0A1D8PKX2	Q59P51	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	Checkpoint protein; Belongs to the HUS1 family.	0.999
CaO19.366	RAD50	A0A1D8PKX2	A0A1D8PJD1	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	MRX complex DNA-binding subunit.	0.595
CaO19.366	RAD51	A0A1D8PKX2	Q59UY8	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.754
CaO19.366	RFA1	A0A1D8PKX2	Q5ACX4	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.864
CaO19.5212	SMT3	A0A1D8PHK1	Q59W54	SUMO ligase.	SUMO family protein.	0.471
DDC1	CaO19.2922	A0A1D8PJM0	A0A1D8PMI3	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	TBPIP domain-containing protein.	0.539
DDC1	CaO19.366	A0A1D8PJM0	A0A1D8PKX2	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family.	0.999
DDC1	DLH1	A0A1D8PJM0	A0A1D8PFE4	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Recombinase; Belongs to the RecA family.	0.617
DDC1	MCD1	A0A1D8PJM0	A0A1D8PU88	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Kleisin alpha.	0.519
DDC1	MEC3	A0A1D8PJM0	Q59P51	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Checkpoint protein; Belongs to the HUS1 family.	0.999
DDC1	RAD50	A0A1D8PJM0	A0A1D8PJD1	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	MRX complex DNA-binding subunit.	0.609
DDC1	RAD51	A0A1D8PJM0	Q59UY8	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily.	0.782
DDC1	RFA1	A0A1D8PJM0	Q5ACX4	DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation.	Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.	0.949
DLH1	CaO19.2922	A0A1D8PFE4	A0A1D8PMI3	Recombinase; Belongs to the RecA family.	TBPIP domain-containing protein.	0.699