15 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MSH2	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR). (873 aa)
	MSH3	DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...] (1037 aa)
	POL30	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
	RNH35	Ribonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (431 aa)
	CaO19.6722	Uncharacterized protein. (709 aa)
	RAD10	Rad10p. (338 aa)
	CaO19.496	Mismatch repair ATPase. (923 aa)
	CaO19.2579	MutS family protein. (803 aa)
	EXO1	Rad2 family nuclease. (699 aa)
	CaO19.1310	Uncharacterized protein. (543 aa)
	CaO19.2713	MutS family protein. (802 aa)
	PMS1	ATP-binding mismatch repair protein. (910 aa)
	MLH3	Mismatch repair protein. (636 aa)
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1214 aa)
	MLH1	Mismatch repair ATPase. (717 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CaO19.1310	CaO19.6722	A0A1D8PLW0	Q5ADX0	Uncharacterized protein.	Uncharacterized protein.	0.595
CaO19.1310	MLH1	A0A1D8PLW0	Q59SL0	Uncharacterized protein.	Mismatch repair ATPase.	0.576
CaO19.1310	MLH3	A0A1D8PLW0	A0A1D8PFX1	Uncharacterized protein.	Mismatch repair protein.	0.559
CaO19.1310	MSH2	A0A1D8PLW0	Q5A102	Uncharacterized protein.	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR).	0.625
CaO19.1310	MSH6	A0A1D8PLW0	A0A1D8PFM1	Uncharacterized protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.574
CaO19.1310	PMS1	A0A1D8PLW0	A0A1D8PII6	Uncharacterized protein.	ATP-binding mismatch repair protein.	0.563
CaO19.1310	RAD10	A0A1D8PLW0	Q5AA15	Uncharacterized protein.	Rad10p.	0.710
CaO19.2579	CaO19.2713	A0A1D8PS25	A0A1D8PLP6	MutS family protein.	MutS family protein.	0.998
CaO19.2579	CaO19.496	A0A1D8PS25	A0A1D8PSP4	MutS family protein.	Mismatch repair ATPase.	0.552
CaO19.2579	CaO19.6722	A0A1D8PS25	Q5ADX0	MutS family protein.	Uncharacterized protein.	0.412
CaO19.2579	EXO1	A0A1D8PS25	A0A1D8PMZ2	MutS family protein.	Rad2 family nuclease.	0.766
CaO19.2579	MLH1	A0A1D8PS25	Q59SL0	MutS family protein.	Mismatch repair ATPase.	0.937
CaO19.2579	MLH3	A0A1D8PS25	A0A1D8PFX1	MutS family protein.	Mismatch repair protein.	0.945
CaO19.2579	MSH2	A0A1D8PS25	Q5A102	MutS family protein.	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR).	0.698
CaO19.2579	MSH3	A0A1D8PS25	Q59Y41	MutS family protein.	DNA mismatch repair protein MSH3; Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS beta, which binds to DNA mismatches thereby initiating DNA repair. MSH3 provides substrate- binding and substrate specificity to the complex. When bound, the MutS beta heterodimer bends the DNA helix and shields approximately 20 base pairs. Acts mainly to repair insertion-deletion loops (IDLs) from 2 to 13 nucleotides in size, but can also repair base-base and single insertion-deletion mismatches that occur during replication. After mismatch bindi [...]	0.679
CaO19.2579	MSH6	A0A1D8PS25	A0A1D8PFM1	MutS family protein.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.720
CaO19.2579	PMS1	A0A1D8PS25	A0A1D8PII6	MutS family protein.	ATP-binding mismatch repair protein.	0.938
CaO19.2579	POL30	A0A1D8PS25	Q5AMN0	MutS family protein.	Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.	0.654
CaO19.2579	RAD10	A0A1D8PS25	Q5AA15	MutS family protein.	Rad10p.	0.707
CaO19.2713	CaO19.2579	A0A1D8PLP6	A0A1D8PS25	MutS family protein.	MutS family protein.	0.998