13 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MCD1	Kleisin alpha. (564 aa)
	CaO19.5053	Uncharacterized protein. (260 aa)
	CaO19.1834	Uncharacterized protein. (910 aa)
	RAD32	DNA-directed DNA polymerase eta. (640 aa)
	PDS5	Pds5p. (1303 aa)
	SMC3	Structural maintenance of chromosomes protein. (1237 aa)
	CaO19.3080	Sister chromatid cohesion protein. (1046 aa)
	CaO19.3169	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (352 aa)
	DCC1	Dcc1p. (339 aa)
	NAT5	Peptide alpha-N-acetyltransferase subunit. (175 aa)
	CTF8	Ctf8p. (162 aa)
	CaO19.3130	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (273 aa)
	CaO19.5934	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CTF8	CaO19.5053	Q59XA3	A0A1D8PE50	Ctf8p.	Uncharacterized protein.	0.583
CTF8	DCC1	Q59XA3	A0A1D8PQK7	Ctf8p.	Dcc1p.	0.999
CTF8	MCD1	Q59XA3	A0A1D8PU88	Ctf8p.	Kleisin alpha.	0.640
CTF8	SMC3	Q59XA3	A0A1D8PJK7	Ctf8p.	Structural maintenance of chromosomes protein.	0.710
CaO19.3080	CaO19.5053	A0A1D8PMS8	A0A1D8PE50	Sister chromatid cohesion protein.	Uncharacterized protein.	0.679
CaO19.3080	MCD1	A0A1D8PMS8	A0A1D8PU88	Sister chromatid cohesion protein.	Kleisin alpha.	0.998
CaO19.3080	PDS5	A0A1D8PMS8	A0A1D8PHZ6	Sister chromatid cohesion protein.	Pds5p.	0.948
CaO19.3080	SMC3	A0A1D8PMS8	A0A1D8PJK7	Sister chromatid cohesion protein.	Structural maintenance of chromosomes protein.	0.998
CaO19.3130	CaO19.3169	Q5A0W6	A0A1D8PNA7	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.616
CaO19.3169	CaO19.3130	A0A1D8PNA7	Q5A0W6	GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	GPN-loop GTPase 3; Small GTPase required for proper nuclear import of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family.	0.616
CaO19.5053	CTF8	A0A1D8PE50	Q59XA3	Uncharacterized protein.	Ctf8p.	0.583
CaO19.5053	CaO19.3080	A0A1D8PE50	A0A1D8PMS8	Uncharacterized protein.	Sister chromatid cohesion protein.	0.679
CaO19.5053	DCC1	A0A1D8PE50	A0A1D8PQK7	Uncharacterized protein.	Dcc1p.	0.666
CaO19.5053	MCD1	A0A1D8PE50	A0A1D8PU88	Uncharacterized protein.	Kleisin alpha.	0.908
CaO19.5053	PDS5	A0A1D8PE50	A0A1D8PHZ6	Uncharacterized protein.	Pds5p.	0.965
CaO19.5053	SMC3	A0A1D8PE50	A0A1D8PJK7	Uncharacterized protein.	Structural maintenance of chromosomes protein.	0.992
CaO19.5934	PDS5	Q5ANG9	A0A1D8PHZ6	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Pds5p.	0.422
CaO19.5934	RAD32	Q5ANG9	A0A1D8PGZ5	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	DNA-directed DNA polymerase eta.	0.597
CaO19.5934	SMC3	Q5ANG9	A0A1D8PJK7	DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.	Structural maintenance of chromosomes protein.	0.403
DCC1	CTF8	A0A1D8PQK7	Q59XA3	Dcc1p.	Ctf8p.	0.999