STRINGSTRING
CaO19.7344 CaO19.7344 CaO19.808 CaO19.808 RXT3 RXT3 HOS2 HOS2 CaO19.6952 CaO19.6952 CaO19.132 CaO19.132 SWD3 SWD3 CaO19.6506 CaO19.6506 UME1 UME1 RPD3 RPD3 CaO19.1856 CaO19.1856 EAF3 EAF3 CaO19.4615 CaO19.4615 RPD31 RPD31 HDA1 HDA1 CaO19.3581 CaO19.3581 SET2 SET2 HAT2 HAT2 SIN3 SIN3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.7344Uncharacterized protein. (835 aa)
CaO19.808Rpd3L histone deacetylase complex subunit. (610 aa)
RXT3Rxt3p. (517 aa)
HOS2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (454 aa)
CaO19.6952Uncharacterized protein. (669 aa)
CaO19.132Uncharacterized protein. (593 aa)
SWD3Swd3p. (383 aa)
CaO19.6506PHD-type domain-containing protein. (688 aa)
UME1Ume1p. (485 aa)
RPD3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
CaO19.1856Uncharacterized protein. (340 aa)
EAF3Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (369 aa)
CaO19.4615RXT2_N domain-containing protein. (318 aa)
RPD31Histone deacetylase. (577 aa)
HDA1Histone deacetylase HDA1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates the YNG2 subunit of NuA4 histone acetyltransferase (HAT) module, leading to the reduction of YNG2 and NuA4 HAT at the promoters of hypha-specific genes. Plays a key role in the regulation o [...] (833 aa)
CaO19.3581WD_REPEATS_REGION domain-containing protein. (435 aa)
SET2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (844 aa)
HAT2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. (382 aa)
SIN3Transcriptional regulator. (1411 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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