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CYB5 CYB5 CaO19.3290 CaO19.3290 CaO19.3353 CaO19.3353 CaO19.4468 CaO19.4468 A0A1D8PDP8 A0A1D8PDP8 CaO19.4727 CaO19.4727 CaO19.4758 CaO19.4758 A0A1D8PEJ9 A0A1D8PEJ9 COX6 COX6 QCR8 QCR8 CYT1 CYT1 COX9 COX9 COX8 COX8 CaO19.2175 CaO19.2175 TAZ1 TAZ1 ALI1 ALI1 YAH1 YAH1 A0A1D8PJT8 A0A1D8PJT8 RIP1 RIP1 QCR9 QCR9 NCP1 NCP1 CaO19.2671 CaO19.2671 AIF1 AIF1 CaO19.1438 CaO19.1438 CaO19.3175 CaO19.3175 CaO19.4016 CaO19.4016 COX15 COX15 CaO19.5547 CaO19.5547 YMX6 YMX6 A0A1D8PQD5 A0A1D8PQD5 CaO19.2150 CaO19.2150 CaO19.7194 CaO19.7194 CaO19.6612 CaO19.6612 CaO19.7591 CaO19.7591 COX1 COX1 COB COB CYC1 CYC1 QCR2 QCR2 YFH1 YFH1 SDH2 SDH2 NDH51 NDH51 CaO19.3611 CaO19.3611 SDH12 SDH12 DRE2 DRE2 CaO19.2821 CaO19.2821 SDH1 SDH1 OLE1 OLE1 MCI4 MCI4 PSD1 PSD1 QCR7 QCR7 FESUR1 FESUR1 NUC2 NUC2 SDH4 SDH4 AGC1 AGC1 CaO19.1480 CaO19.1480 COX4 COX4 COX13 COX13 COX5 COX5 COX3A COX3A NAD4 NAD4 NAD5 NAD5 NAD4L NAD4L NAD3 NAD3 NAD2 NAD2 NAD1 NAD1 NAD6 NAD6 COX2 COX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYB5Cyb5p; Belongs to the cytochrome b5 family. (126 aa)
CaO19.3290Uncharacterized protein. (156 aa)
CaO19.3353CIA30 domain-containing protein. (227 aa)
CaO19.4468Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (169 aa)
A0A1D8PDP8Ubiquinol--cytochrome-c reductase subunit 10. (78 aa)
CaO19.4727Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit of the SDH catalytic dimer. (155 aa)
CaO19.4758Uncharacterized protein. (247 aa)
A0A1D8PEJ9Uncharacterized protein. (74 aa)
COX6Cytochrome c oxidase subunit VI. (150 aa)
QCR8Ubiquinol--cytochrome-c reductase subunit 8. (95 aa)
CYT1Ubiquinol--cytochrome-c reductase catalytic subunit. (288 aa)
COX9Cytochrome c oxidase subunit 7A; This small integral protein plays a role in holoenzyme assembly or stability. (61 aa)
COX8Cytochrome c oxidase subunit VIII. (93 aa)
CaO19.2175Pyr_redox_2 domain-containing protein. (367 aa)
TAZ1Tafazzin family protein; Belongs to the taffazin family. (410 aa)
ALI1Ali1p; Belongs to the complex I 30 kDa subunit family. (279 aa)
YAH1Adrenodoxin. (169 aa)
A0A1D8PJT8Ubiquinol--cytochrome-c reductase subunit 6. (135 aa)
RIP1Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (213 aa)
QCR9Ubiquinol--cytochrome-c reductase subunit 9. (65 aa)
NCP1NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (680 aa)
CaO19.2671Pyr_redox_2 domain-containing protein. (447 aa)
AIF1Pyr_redox_2 domain-containing protein. (447 aa)
CaO19.1438Pyr_redox_2 domain-containing protein. (407 aa)
CaO19.3175Electron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (627 aa)
CaO19.4016Ubiquinol--cytochrome-c reductase subunit. (439 aa)
COX15Cox15p. (479 aa)
CaO19.5547Uncharacterized protein; Belongs to the complex I LYR family. (107 aa)
YMX6Ymx6p. (622 aa)
A0A1D8PQD5Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (83 aa)
CaO19.2150ETF domain-containing protein. (329 aa)
CaO19.7194Uncharacterized protein. (308 aa)
CaO19.6612ETF domain-containing protein. (266 aa)
CaO19.7591Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (720 aa)
COX1Cytochrome c oxidase subunit 1; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (531 aa)
COBCytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (387 aa)
CYC1Cytochrome c; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (110 aa)
QCR2Cytochrome b-c1 complex subunit 2, mitochondrial; Component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradie [...] (374 aa)
YFH1Ferroxidase. (177 aa)
SDH2Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (263 aa)
NDH51NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. (490 aa)
CaO19.3611zf-CHCC domain-containing protein. (157 aa)
SDH12Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (641 aa)
DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] (409 aa)
CaO19.2821NADH-ubiquinone oxidoreductase; Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (175 aa)
SDH1Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (638 aa)
OLE1Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (486 aa)
MCI4Mci4p. (139 aa)
PSD1Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity). Important for virulence. (590 aa)
QCR7Cytochrome b-c1 complex subunit 7; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain; Belongs to the UQCRB/QCR7 family. (127 aa)
FESUR1Fesur1p; Belongs to the complex I 20 kDa subunit family. (223 aa)
NUC2Nuc2p; Belongs to the complex I 49 kDa subunit family. (478 aa)
SDH4Succinate dehydrogenase [ubiquinone] cytochrome b small subunit. (164 aa)
AGC1Amino acid transporter; Belongs to the mitochondrial carrier (TC 2.A.29) family. (731 aa)
CaO19.1480Uncharacterized protein. (176 aa)
COX4Cytochrome c oxidase subunit IV. (157 aa)
COX13Cytochrome c oxidase subunit 6A, mitochondrial. (134 aa)
COX5Cytochrome c oxidase subunit Va. (165 aa)
COX3ACytochrome c oxidase subunit 3; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (269 aa)
NAD4NADH-ubiquinone oxidoreductase chain 4; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (464 aa)
NAD5NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (552 aa)
NAD4LNADH-ubiquinone oxidoreductase chain 4L; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (84 aa)
NAD3NADH-ubiquinone oxidoreductase chain 3; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (129 aa)
NAD2NADH-ubiquinone oxidoreductase chain 2; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (475 aa)
NAD1NADH-ubiquinone oxidoreductase chain 1; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (317 aa)
NAD6NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). (146 aa)
COX2Cytochrome c oxidase subunit 2; Component of the cytochrome c oxidase, the last enzyme in the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol- cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and t [...] (262 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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