STRINGSTRING
CaO19.7452 CaO19.7452 MCM6 MCM6 CDC45 CDC45 SLD5 SLD5 PSF2 PSF2 CDC46 CDC46 PSF1 PSF1 ORC3 ORC3 SLD2 SLD2 MCM2 MCM2 PSF3 PSF3 CDC54 CDC54 MCM3 MCM3 CDC47 CDC47
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.7452SLD3 domain-containing protein. (736 aa)
MCM6DNA helicase; Belongs to the MCM family. (880 aa)
CDC45DNA replication initiation factor. (579 aa)
SLD5DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (236 aa)
PSF2DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (203 aa)
CDC46DNA helicase; Belongs to the MCM family. (728 aa)
PSF1DNA replication complex GINS protein PSF1; The GINS complex plays an essential role in the initiation of DNA replication. (236 aa)
ORC3Origin recognition complex subunit 3. (682 aa)
SLD2DNA replication regulator SLD2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (354 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
PSF3DNA replication complex GINS protein PSF3; The GINS complex plays an essential role in the initiation of DNA replication. (177 aa)
CDC54DNA helicase; Belongs to the MCM family. (912 aa)
MCM3DNA helicase; Belongs to the MCM family. (878 aa)
CDC47DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (781 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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