STRINGSTRING
CDC46 CDC46 HAT1 HAT1 SAS2 SAS2 ASF1 ASF1 INO80 INO80 UBC2 UBC2 CaO19.3890 CaO19.3890 SUB2 SUB2 CDC47 CDC47 MCM3 MCM3 GTR1 GTR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CDC46DNA helicase; Belongs to the MCM family. (728 aa)
HAT1Histone acetyltransferase type B catalytic subunit; Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair; Belongs to the HAT1 family. (413 aa)
SAS2Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (352 aa)
ASF1Histone chaperone ASF1; Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. (247 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1387 aa)
UBC2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation. (179 aa)
CaO19.3890DNA-dependent ATPase. (1097 aa)
SUB2ATP-dependent RNA helicase. (433 aa)
CDC47DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (781 aa)
MCM3DNA helicase; Belongs to the MCM family. (878 aa)
GTR1Rag GTPase. (352 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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