STRINGSTRING
CaO19.7033 CaO19.7033 POL3 POL3 MCM6 MCM6 CDC45 CDC45 PSF2 PSF2 CDC46 CDC46 PSF1 PSF1 SLD2 SLD2 RAD51 RAD51 SMT3 SMT3 RPN10 RPN10 MCM2 MCM2 CaO19.2472 CaO19.2472 PSF3 PSF3 CaO19.1476 CaO19.1476 POL30 POL30 CaO19.5934 CaO19.5934 CDC54 CDC54 CDC7 CDC7 MCM3 MCM3 CDC47 CDC47 CaO19.6155 CaO19.6155 POL1 POL1 PPS1 PPS1 CAC2 CAC2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.7033Tyrosine/serine/threonine protein phosphatase. (1076 aa)
POL3DNA polymerase. (1038 aa)
MCM6DNA helicase; Belongs to the MCM family. (880 aa)
CDC45DNA replication initiation factor. (579 aa)
PSF2DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (203 aa)
CDC46DNA helicase; Belongs to the MCM family. (728 aa)
PSF1DNA replication complex GINS protein PSF1; The GINS complex plays an essential role in the initiation of DNA replication. (236 aa)
SLD2DNA replication regulator SLD2; Has a role in the initiation of DNA replication. Required at S-phase checkpoint (By similarity); Belongs to the SLD2 family. (354 aa)
RAD51DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (361 aa)
SMT3SUMO family protein. (102 aa)
RPN10Proteasome regulatory particle base subunit. (279 aa)
MCM2DNA helicase; Belongs to the MCM family. (903 aa)
CaO19.2472Rtf2 domain-containing protein. (230 aa)
PSF3DNA replication complex GINS protein PSF3; The GINS complex plays an essential role in the initiation of DNA replication. (177 aa)
CaO19.1476mRNA (N6-adenosine)-methyltransferase; Belongs to the MT-A70-like family. (543 aa)
POL30Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
CaO19.5934DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa)
CDC54DNA helicase; Belongs to the MCM family. (912 aa)
CDC7Serine/threonine protein kinase. (656 aa)
MCM3DNA helicase; Belongs to the MCM family. (878 aa)
CDC47DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (781 aa)
CaO19.6155DNA ligase. (770 aa)
POL1DNA polymerase. (1470 aa)
PPS1Pps1p. (1018 aa)
CAC2Cac2p. (460 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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