STRINGSTRING
UBC2 UBC2 RAD10 RAD10 CaO19.2225 CaO19.2225 POL30 POL30 RFX2 RFX2 RFC1 RFC1 RAD23 RAD23 CaO19.7213 CaO19.7213 POL32 POL32 RSP5 RSP5 RAD52 RAD52 RAD14 RAD14 RAD2 RAD2 RFC2 RFC2 POL3 POL3 CaO19.607 CaO19.607
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
UBC2Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation. (179 aa)
RAD10Rad10p. (338 aa)
CaO19.2225E2 ubiquitin-conjugating protein; Belongs to the ubiquitin-conjugating enzyme family. (169 aa)
POL30Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (259 aa)
RFX2RFX-like DNA-binding protein RFX2; Transcriptional repressor which regulates DNA damage responses, morphogenesis, and virulence. Involved in the regulation of filamentous growth through its repression of hyphal-specific genes such as HWP1, ALS3, HYR1, ECE1, and CEK1; Belongs to the RFX family. (1111 aa)
RFC1Replication factor C subunit 1. (888 aa)
RAD23Rad23p. (416 aa)
CaO19.7213ATP-dependent 3'-5' DNA helicase. (1123 aa)
POL32DNA polymerase delta subunit. (403 aa)
RSP5E3 ubiquitin-protein ligase. (832 aa)
RAD52Recombinase. (564 aa)
RAD14DNA repair protein RAD14; Involved in DNA excision repair; Belongs to the XPA family. (396 aa)
RAD2SsDNA endodeoxyribonuclease. (990 aa)
RFC2Replication factor C subunit 2. (363 aa)
POL3DNA polymerase. (1038 aa)
CaO19.607DNA-dependent ATPase. (1055 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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