STRINGSTRING
CLF1 CLF1 CaO19.3250 CaO19.3250 PRP46 PRP46 PRP8 PRP8 CWC2 CWC2 CaO19.763 CaO19.763 CWC15 CWC15 YHC1 YHC1 CaO19.4326 CaO19.4326 A0A1D8PM82 A0A1D8PM82 CaO19.4659 CaO19.4659 PRP39 PRP39 CaO19.6356 CaO19.6356 CEF1 CEF1 PRP3 PRP3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CLF1Pre-mRNA-splicing factor CLF1; Involved in pre-mRNA splicing and cell cycle progression. Required for the spliceosome assembly and initiation of the DNA replication (By similarity). (701 aa)
CaO19.3250Uncharacterized protein. (602 aa)
PRP46Pre-mRNA-splicing factor PRP46; Involved in pre-mRNA splicing and required for cell cycle progression at G2/M. (389 aa)
PRP8U4/U6-U5 snRNP complex subunit. (2416 aa)
CWC2Pre-mRNA-splicing factor CWC2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the 'nineteen complex' NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled active spliceosomes. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic [...] (363 aa)
CaO19.763Nuclear cap-binding protein subunit 2. (224 aa)
CWC15Pre-mRNA-splicing factor CWC15; Involved in pre-mRNA splicing. (224 aa)
YHC1U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (150 aa)
CaO19.4326U4/U6-U5 snRNP complex subunit. (673 aa)
A0A1D8PM82Ubiquitin-like protein. (73 aa)
CaO19.4659Uncharacterized protein. (425 aa)
PRP39Prp39p. (647 aa)
CaO19.6356U4/U6-U5 snRNP complex subunit. (911 aa)
CEF1Pre-mRNA-splicing factor CEF1; Involved in pre-mRNA splicing and cell cycle control. (610 aa)
PRP3U4/U6-U5 snRNP complex subunit. (446 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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