STRINGSTRING
CaO19.3648 CaO19.3648 TOP2 TOP2 ESP1 ESP1 CaO19.1792 CaO19.1792 RAD1 RAD1 CaO19.7594 CaO19.7594 MUS81 MUS81 HRR25 HRR25 SMC5 SMC5 CDC23 CDC23 CDC5 CDC5 MHF1 MHF1 MPS1 MPS1 RPN7 RPN7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.3648ERCC4 domain-containing protein. (587 aa)
TOP2DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1461 aa)
ESP1Separase. (1598 aa)
CaO19.1792Anaphase promoting complex subunit. (785 aa)
RAD1SsDNA endodeoxyribonuclease. (970 aa)
CaO19.7594Uncharacterized protein. (213 aa)
MUS81Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (614 aa)
HRR25Serine/threonine protein kinase; Belongs to the protein kinase superfamily. (433 aa)
SMC5DNA repair ATPase. (1073 aa)
CDC23Anaphase promoting complex subunit. (582 aa)
CDC5Serine/threonine-protein kinase. (653 aa)
MHF1Inner kinetochore subunit MHF1; dsDNA-binding component of a FANCM-MHF complex involved in DNA damage repair and genome maintenance (By similarity). FANCM-MHF promotes gene conversion at blocked replication forks, probably by reversal of the stalled fork (By similarity). Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere- associated network (CCAN), wh [...] (117 aa)
MPS1Serine/threonine/tyrosine protein kinase. (690 aa)
RPN7Proteasome regulatory particle lid subunit. (400 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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