48 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CaO19.2112	mRNA splicing protein. (270 aa)
	CaO19.1548	U4/U6-U5 snRNP complex subunit. (242 aa)
	A0A1D8PH20	Small nuclear ribonucleoprotein G. (74 aa)
	SNU114	U5 snRNP GTPase. (1022 aa)
	CaO19.6866	U1 snRNP complex subunit. (347 aa)
	SMD2	Small nuclear ribonucleoprotein Sm D2. (112 aa)
	CaO19.82	U4/U6-U5 snRNP complex subunit. (569 aa)
	CaO19.2261	U2 snRNP complex subunit. (259 aa)
	CaO19.6989	RRM domain-containing protein. (107 aa)
	CaO19.7375	Uncharacterized protein. (204 aa)
	CaO19.4659	Uncharacterized protein. (425 aa)
	CaO19.3098	ATP-dependent RNA helicase. (1987 aa)
	LSM8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (146 aa)
	CaO19.4326	U4/U6-U5 snRNP complex subunit. (673 aa)
	A0A1D8PNM3	mRNA splicing protein. (127 aa)
	A0A1D8PNP9	Sm-like protein. (123 aa)
	A0A1D8PPC8	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (86 aa)
	CaO19.5767	U2 snRNP complex subunit. (283 aa)
	LSM4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (130 aa)
	LSM6	U4/U6-U5 snRNP complex subunit. (80 aa)
	SNP3	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	CaO19.2368	U5 snRNP complex subunit. (414 aa)
	SMX4	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	CaO19.4724	U1-type domain-containing protein. (256 aa)
	BUD31	U2 snRNP complex subunit. (150 aa)
	SNU13	13 kDa ribonucleoprotein-associated protein; Common component of the spliceosome and rRNA processing machinery. In association with the spliceosomal U4/U6.U5 tri-snRNP particle, required for splicing of pre-mRNA. In association with box C/D snoRNPs, required for processing of pre-ribosomal RNA (rRNA) and site-specific 2'-O-methylation of substrate RNAs. Essential for the accumulation and stability of U4 snRNA, U6 snRNA, and box C/D snoRNAs (By similarity). (126 aa)
	PRP3	U4/U6-U5 snRNP complex subunit. (446 aa)
	CaO19.2675	mRNA-binding U2 snRNP complex subunit. (1094 aa)
	CaO19.3250	Uncharacterized protein. (602 aa)
	RSE1	Pre-mRNA-splicing factor RSE1; Involved in pre-mRNA splicing and cell cycle control. (1219 aa)
	LEA1	U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing. (233 aa)
	PRP8	U4/U6-U5 snRNP complex subunit. (2416 aa)
	CaO19.1975	Spliceosomal protein DIB1; Essential role in pre-mRNA splicing. Also essential for entry into mitosis (G2/M progression) as well as for chromosome segregation during mitosis; Belongs to the DIM1 family. (148 aa)
	EXM2	Exm2p. (240 aa)
	PRP42	mRNA splicing protein. (393 aa)
	CaO19.2230	U2 snRNP complex subunit. (119 aa)
	CaO19.1045	U2 snRNP complex subunit. (353 aa)
	YHC1	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. (150 aa)
	SMD3	Small nuclear ribonucleoprotein Sm D3. (106 aa)
	CaO19.7673	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family. (116 aa)
	CaO19.7581	U2 snRNP complex subunit. (471 aa)
	CaO19.7343	U4/U6-U5 snRNP complex subunit. (458 aa)
	CaO19.2621	mRNA splicing protein. (125 aa)
	CaO19.4748	U2 snRNP complex subunit. (131 aa)
	A0A1D8PF89	Uncharacterized protein. (73 aa)
	CaO19.6356	U4/U6-U5 snRNP complex subunit. (911 aa)
	CaO19.7256	RNA-binding protein. (77 aa)
	PRP39	Prp39p. (647 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A0A1D8PF89	A0A1D8PH20	A0A1D8PF89	A0A1D8PH20	Uncharacterized protein.	Small nuclear ribonucleoprotein G.	0.568
A0A1D8PF89	A0A1D8PPC8	A0A1D8PF89	A0A1D8PPC8	Uncharacterized protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.540
A0A1D8PF89	CaO19.1045	A0A1D8PF89	Q59VP9	Uncharacterized protein.	U2 snRNP complex subunit.	0.558
A0A1D8PF89	CaO19.2230	A0A1D8PF89	Q59Z68	Uncharacterized protein.	U2 snRNP complex subunit.	0.902
A0A1D8PF89	CaO19.2261	A0A1D8PF89	A0A1D8PHX6	Uncharacterized protein.	U2 snRNP complex subunit.	0.900
A0A1D8PF89	CaO19.2621	A0A1D8PF89	A0A1D8PTI0	Uncharacterized protein.	mRNA splicing protein.	0.544
A0A1D8PF89	CaO19.2675	A0A1D8PF89	Q5AFD2	Uncharacterized protein.	mRNA-binding U2 snRNP complex subunit.	0.903
A0A1D8PF89	CaO19.4659	A0A1D8PF89	A0A1D8PL91	Uncharacterized protein.	Uncharacterized protein.	0.542
A0A1D8PF89	CaO19.4724	A0A1D8PF89	Q5APP1	Uncharacterized protein.	U1-type domain-containing protein.	0.540
A0A1D8PF89	CaO19.4748	A0A1D8PF89	A0A1D8PEI3	Uncharacterized protein.	U2 snRNP complex subunit.	0.567
A0A1D8PF89	CaO19.5767	A0A1D8PF89	A0A1D8PQA3	Uncharacterized protein.	U2 snRNP complex subunit.	0.540
A0A1D8PF89	CaO19.6989	A0A1D8PF89	A0A1D8PKA1	Uncharacterized protein.	RRM domain-containing protein.	0.900
A0A1D8PF89	CaO19.7581	A0A1D8PF89	A0A1D8PU52	Uncharacterized protein.	U2 snRNP complex subunit.	0.901
A0A1D8PF89	CaO19.7673	A0A1D8PF89	A0A1D8PUC1	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D1; Involved in pre-mRNA splicing. Binds snRNA U1, U2, U4 and U5 which contain a highly conserved structural motif called the Sm binding site; Belongs to the snRNP core protein family.	0.540
A0A1D8PF89	LEA1	A0A1D8PF89	Q5A449	Uncharacterized protein.	U2 small nuclear ribonucleoprotein A; Involved in pre-mRNA splicing.	0.552
A0A1D8PF89	RSE1	A0A1D8PF89	Q5A7S5	Uncharacterized protein.	Pre-mRNA-splicing factor RSE1; Involved in pre-mRNA splicing and cell cycle control.	0.900
A0A1D8PF89	SMD2	A0A1D8PF89	A0A1D8PHP3	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D2.	0.542
A0A1D8PF89	SMD3	A0A1D8PF89	Q59NQ6	Uncharacterized protein.	Small nuclear ribonucleoprotein Sm D3.	0.543
A0A1D8PH20	A0A1D8PF89	A0A1D8PH20	A0A1D8PF89	Small nuclear ribonucleoprotein G.	Uncharacterized protein.	0.568
A0A1D8PH20	A0A1D8PNM3	A0A1D8PH20	A0A1D8PNM3	Small nuclear ribonucleoprotein G.	mRNA splicing protein.	0.999