STRINGSTRING
DAD2 DAD2 SIN3 SIN3 CaO19.3295 CaO19.3295 CaO19.3325 CaO19.3325 ARP8 ARP8 CaO19.2964 CaO19.2964 ORC1 ORC1 CaO19.3027 CaO19.3027 CaO19.3035 CaO19.3035 CaO19.3062 CaO19.3062 REC8 REC8 POL32 POL32 CaO19.6260 CaO19.6260 CaO19.6247 CaO19.6247 CaO19.4437 CaO19.4437 CaO19.5053 CaO19.5053 CaO19.5069 CaO19.5069 CaO19.2796 CaO19.2796 CaO19.5093 CaO19.5093 CaO19.4729 CaO19.4729 GIN1 GIN1 SNT1 SNT1 DLH1 DLH1 DAD1 DAD1 SET3 SET3 CaO19.7234 CaO19.7234 DPB4 DPB4 CaO19.2070 CaO19.2070 NPL6 NPL6 CaO19.2041 CaO19.2041 CaO19.835 CaO19.835 SNF6 SNF6 CaO19.808 CaO19.808 TAF14 TAF14 CaO19.810 CaO19.810 CaO19.4502 CaO19.4502 CaO19.4488 CaO19.4488 CaO19.187 CaO19.187 RXT3 RXT3 CaO19.5212 CaO19.5212 CaO19.2265 CaO19.2265 CaO19.2266 CaO19.2266 PDS5 PDS5 CaO19.3625 CaO19.3625 CaO19.3604 CaO19.3604 SPO11 SPO11 CaO19.1368 CaO19.1368 PHO23 PHO23 HOS2 HOS2 CaO19.1731 CaO19.1731 CaO19.239 CaO19.239 SMC3 SMC3 CaO19.314 CaO19.314 DDC1 DDC1 CaO19.6952 CaO19.6952 SNF5 SNF5 POL1 POL1 CaO19.366 CaO19.366 CaO19.4677 CaO19.4677 CaO19.4639 CaO19.4639 UME7 UME7 HOS1 HOS1 AGO1 AGO1 PRI2 PRI2 CaO19.2889 CaO19.2889 ORC4 ORC4 CaO19.6667 CaO19.6667 CaO19.4030 CaO19.4030 DNA2 DNA2 TOP1 TOP1 CaO19.132 CaO19.132 CaO19.3399 CaO19.3399 CaO19.5510 CaO19.5510 CaO19.5555 CaO19.5555 CaO19.5617 CaO19.5617 CaO19.7101 CaO19.7101 CaO19.7023 CaO19.7023 CaO19.6506 CaO19.6506 POL3 POL3 ZCF29 ZCF29 UME1 UME1 CaO19.7506 CaO19.7506 RPD3 RPD3 CaO19.652 CaO19.652 CaO19.5844 CaO19.5844 CaO19.1856 CaO19.1856 POL2 POL2 DAD4 DAD4 CaO19.7344 CaO19.7344 DPB2 DPB2 MCD1 MCD1 SLD5 SLD5 DEF1 DEF1 ADF1 ADF1 SPT6 SPT6 EAF3 EAF3 INO80 INO80 YAF9 YAF9 CaO19.190 CaO19.190 PSF2 PSF2 UME6 UME6 RAD52 RAD52 YBL053 YBL053 MEC3 MEC3 DUO1 DUO1 CaO19.29 CaO19.29 SPC19 SPC19 HAT2 HAT2 CaO19.6142 CaO19.6142 PSF1 PSF1 CaO19.2369 CaO19.2369 ORC3 ORC3 CaO19.4544 CaO19.4544 ZCF3 ZCF3 CaO19.1143 CaO19.1143 GRC3 GRC3 SWR1 SWR1 SWI1 SWI1 RAD51 RAD51 DAD3 DAD3 SMT3 SMT3 CaO19.4441 CaO19.4441 CSM3 CSM3 SET2 SET2 MTW1 MTW1 RFA2 RFA2 CaO19.3581 CaO19.3581 NOP1 NOP1 RVB1 RVB1 VID21 VID21 CDC68 CDC68 ISW2 ISW2 UBC9 UBC9 SLX1 SLX1 CaO19.5358 CaO19.5358 CaO19.504 CaO19.504 JHD1 JHD1 CTF18 CTF18 SWC5 SWC5 CaO19.3306 CaO19.3306 CaO19.3289 CaO19.3289 HDA1 HDA1 CaO19.2519 CaO19.2519 ARP9 ARP9 CaO19.2473 CaO19.2473 SWC4 SWC4 CaO19.6199 CaO19.6199 CDC5 CDC5 ASA1 ASA1 ARP4 ARP4 RFA1 RFA1 RPD31 RPD31 CaO19.340 CaO19.340 PSF3 PSF3 SLX4 SLX4 RVB2 RVB2 HFL1 HFL1 CaO19.2985 CaO19.2985 SFL2 SFL2 HYS2 HYS2 POB3 POB3 CaO19.1441 CaO19.1441 ASK1 ASK1 CaO19.4615 CaO19.4615 CaO19.5890 CaO19.5890 ARP6 ARP6 DAM1 DAM1 CaO19.4830 CaO19.4830
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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DAD2DASH complex subunit DAD2; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity). (125 aa)
SIN3Transcriptional regulator. (1411 aa)
CaO19.3295Uncharacterized protein. (474 aa)
CaO19.3325Glycogenin glucosyltransferase. (660 aa)
ARP8Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (1066 aa)
CaO19.2964Uncharacterized protein. (795 aa)
ORC1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (805 aa)
CaO19.3027Uncharacterized protein; Belongs to the actin family. (378 aa)
CaO19.3035Chromatin-remodeling ATPase. (1410 aa)
CaO19.3062Uncharacterized protein. (1179 aa)
REC8Rad21_Rec8_N domain-containing protein. (635 aa)
POL32DNA polymerase delta subunit. (403 aa)
CaO19.6260Putative ubiquitin-specific protease; Belongs to the peptidase C19 family. (1372 aa)
CaO19.6247Chromatin-binding protein. (871 aa)
CaO19.4437Chromatin-remodeling ATPase. (1017 aa)
CaO19.5053Uncharacterized protein. (260 aa)
CaO19.5069Uncharacterized protein. (243 aa)
CaO19.2796DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (664 aa)
CaO19.5093Uncharacterized protein. (352 aa)
CaO19.4729ANK_REP_REGION domain-containing protein. (1381 aa)
GIN1Chromatin-modulating protein. (1234 aa)
SNT1Snt1p. (1001 aa)
DLH1Recombinase; Belongs to the RecA family. (324 aa)
DAD1Dad1p. (99 aa)
SET3Histone-binding protein. (1069 aa)
CaO19.7234Uncharacterized protein. (561 aa)
DPB4DNA polymerase epsilon noncatalytic subunit. (261 aa)
CaO19.2070Uncharacterized protein. (568 aa)
NPL6Npl6p. (449 aa)
CaO19.2041Uncharacterized protein. (636 aa)
CaO19.835Uncharacterized protein. (786 aa)
SNF6Uncharacterized protein. (505 aa)
CaO19.808Rpd3L histone deacetylase complex subunit. (610 aa)
TAF14TATA-binding protein-associated factor. (263 aa)
CaO19.810Uncharacterized protein. (1247 aa)
CaO19.4502DNA-binding ATPase. (1915 aa)
CaO19.4488Uncharacterized protein. (971 aa)
CaO19.187Uncharacterized protein. (816 aa)
RXT3Rxt3p. (517 aa)
CaO19.5212SUMO ligase. (366 aa)
CaO19.2265SWIB domain-containing protein. (469 aa)
CaO19.2266Uncharacterized protein. (830 aa)
PDS5Pds5p. (1303 aa)
CaO19.3625Uncharacterized protein. (349 aa)
CaO19.3604PAPA-1 domain-containing protein. (382 aa)
SPO11Spo11p. (309 aa)
CaO19.1368Uncharacterized protein. (607 aa)
PHO23Chromatin modification-related protein. (481 aa)
HOS2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (454 aa)
CaO19.1731HMG box domain-containing protein. (311 aa)
CaO19.239RSC chromatin remodeling complex ATPase subunit. (1302 aa)
SMC3Structural maintenance of chromosomes protein. (1237 aa)
CaO19.314Uncharacterized protein. (999 aa)
DDC1DNA repair protein rad9; Acts in DNA repair and mutagenesis. Involved in promoting resistance to ionizing radiation and UV light, as well as regulating cell cycle progression after irradiation. (488 aa)
CaO19.6952Uncharacterized protein. (669 aa)
SNF5Snf5p. (696 aa)
POL1DNA polymerase. (1470 aa)
CaO19.366DNA damage checkpoint control protein RAD17; Component of the checkpoint clamp complex involved in the surveillance mechanism that allows the DNA repair pathways to act to restore the integrity of the DNA prior to DNA synthesis or separation of the replicated chromosomes; Belongs to the rad1 family. (336 aa)
CaO19.4677HIT-type domain-containing protein. (236 aa)
CaO19.4639Uncharacterized protein. (224 aa)
UME7DNA-binding transcriptional regulator. (458 aa)
HOS1Histone deacetylase. (436 aa)
AGO1Ago1p; Belongs to the argonaute family. (917 aa)
PRI2DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. (543 aa)
CaO19.2889YL1_C domain-containing protein. (137 aa)
ORC4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (564 aa)
CaO19.6667SAP30_Sin3_bdg domain-containing protein. (168 aa)
CaO19.4030DNA primase; Belongs to the eukaryotic-type primase small subunit family. (424 aa)
DNA2Bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease. (1426 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (780 aa)
CaO19.132Uncharacterized protein. (593 aa)
CaO19.3399YL1_C domain-containing protein. (764 aa)
CaO19.5510WAC domain-containing protein. (1272 aa)
CaO19.5555Uncharacterized protein. (1131 aa)
CaO19.5617PHD domain-containing protein. (479 aa)
CaO19.7101Telomere_reg-2 domain-containing protein. (788 aa)
CaO19.7023PWWP domain-containing protein. (393 aa)
CaO19.6506PHD-type domain-containing protein. (688 aa)
POL3DNA polymerase. (1038 aa)
ZCF29Zcf29p. (1105 aa)
UME1Ume1p. (485 aa)
CaO19.7506Uncharacterized protein. (407 aa)
RPD3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
CaO19.652Crossover junction endodeoxyribonuclease. (684 aa)
CaO19.5844Uncharacterized protein. (184 aa)
CaO19.1856Uncharacterized protein. (340 aa)
POL2DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2211 aa)
DAD4Dad4p. (77 aa)
CaO19.7344Uncharacterized protein. (835 aa)
DPB2DNA polymerase epsilon noncatalytic subunit. (708 aa)
MCD1Kleisin alpha. (564 aa)
SLD5DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (236 aa)
DEF1Transcriptional regulator DEF1; Transcriptional regulator involved in extension of germ tubes into elongated hyphae and maintenance of filamentous growth. Regulates expression of UME6. Acts in a pathway that regulates maintenance of hyphal growth by repressing hyphal-to-yeast transition and allows dissemination within host epithelial tissues. Dispensable for invasion into both host oral epithelial cells and enterocytes, but required for epithelial damage. (887 aa)
ADF1Adherence factor; Surface antigen mediating adhesion and aggregation in S.cerevisiae. (612 aa)
SPT6Transcription elongation factor SPT6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1401 aa)
EAF3Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (369 aa)
INO80Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1387 aa)
YAF9Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (254 aa)
CaO19.190Uncharacterized protein. (324 aa)
PSF2DNA replication complex GINS protein PSF2; The GINS complex plays an essential role in the initiation of DNA replication. Has a role in chromosome segregation (By similarity). (203 aa)
UME6Transcriptional regulatory protein UME6; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). UME6 controls the level and duration of gene expression in the filamentous growth program such as HGC1; and is specifically important for hyphal elongation and germ tube formation. Promo [...] (843 aa)
RAD52Recombinase. (564 aa)
YBL053Topoisomerase 1-associated factor 1; Forms a fork protection complex (FPC) with CSM3 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (1263 aa)
MEC3Checkpoint protein; Belongs to the HUS1 family. (319 aa)
DUO1Duo1p. (171 aa)
CaO19.29CDT1_C domain-containing protein. (323 aa)
SPC19DASH complex subunit SPC19; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity). (175 aa)
HAT2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. (382 aa)
CaO19.6142Meiotic nuclear division protein 1; Required for proper homologous chromosome pairing and efficient cross-over and intragenic recombination during meiosis. Belongs to the MND1 family. (201 aa)
PSF1DNA replication complex GINS protein PSF1; The GINS complex plays an essential role in the initiation of DNA replication. (236 aa)
CaO19.2369Origin recognition complex subunit 5. (496 aa)
ORC3Origin recognition complex subunit 3. (682 aa)
CaO19.4544Uncharacterized protein. (239 aa)
ZCF3Zcf3p. (195 aa)
CaO19.1143Uncharacterized protein. (394 aa)
GRC3Polynucleotide 5'-hydroxyl-kinase GRC3; Polynucleotide 5'-kinase involved in rRNA processing. Belongs to the Clp1 family. NOL9/GRC3 subfamily. (686 aa)
SWR1Helicase SWR1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1641 aa)
SWI1Swi1p. (987 aa)
RAD51DNA repair protein RAD51 homolog; Required both for recombination and for the repair of DNA damage caused by X-rays; Belongs to the RecA family. RAD51 subfamily. (361 aa)
DAD3DASH complex subunit DAD2; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity). (138 aa)
SMT3SUMO family protein. (102 aa)
CaO19.4441Zf-primase domain-containing protein. (598 aa)
CSM3Chromosome segregation in meiosis protein 3; Forms a fork protection complex (FPC) with TOF1 and which is required for chromosome segregation during meiosis and DNA damage repair. FPC coordinates leading and lagging strand synthesis and moves with the replication fork. FPC stabilizes replication forks in a configuration that is recognized by replication checkpoint sensors (By similarity). (316 aa)
SET2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (844 aa)
MTW1MIND complex subunit. (314 aa)
RFA2Rfa2p. (272 aa)
CaO19.3581WD_REPEATS_REGION domain-containing protein. (435 aa)
NOP1rRNA methyltransferase. (316 aa)
RVB1RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa)
VID21Chromatin modification-related protein EAF1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (686 aa)
CDC68FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1060 aa)
ISW2ISWI chromatin-remodeling complex ATPase ISW2; Catalytic component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing (By similarity). ISW2 is required for chlamydospore formation, distinctive morphological feature of the fungal pathogen C.albicans that can be induced to form in oxygen-limited environments and has been reported in clinical specimens; Belongs to the SNF2/RAD54 helicase fa [...] (1056 aa)
UBC9E2 SUMO-conjugating protein; Belongs to the ubiquitin-conjugating enzyme family. (219 aa)
SLX1Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (286 aa)
CaO19.5358Origin recognition complex subunit 2. (688 aa)
CaO19.504Uncharacterized protein; Belongs to the actin family. (776 aa)
JHD1JmjC domain-containing histone demethylation protein 1; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. (478 aa)
CTF18Ctf18p. (853 aa)
SWC5SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (338 aa)
CaO19.3306HORMA domain-containing protein. (607 aa)
CaO19.3289Origin recognition complex subunit 6. (363 aa)
HDA1Histone deacetylase HDA1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates the YNG2 subunit of NuA4 histone acetyltransferase (HAT) module, leading to the reduction of YNG2 and NuA4 HAT at the promoters of hypha-specific genes. Plays a key role in the regulation o [...] (833 aa)
CaO19.2519MIND complex subunit. (196 aa)
ARP9Arp9p; Belongs to the actin family. (484 aa)
CaO19.2473RFX-type winged-helix domain-containing protein. (634 aa)
SWC4SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (635 aa)
CaO19.6199ATP-dependent 5'-3' DNA helicase. (719 aa)
CDC5Serine/threonine-protein kinase. (653 aa)
ASA1ASTRA-associated protein 1; Component of the ASTRA complex involved in chromatin remodeling. (377 aa)
ARP4Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...] (468 aa)
RFA1Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. (624 aa)
RPD31Histone deacetylase. (577 aa)
CaO19.340ESCRT-I subunit protein. (199 aa)
PSF3DNA replication complex GINS protein PSF3; The GINS complex plays an essential role in the initiation of DNA replication. (177 aa)
SLX4Structure-specific endonuclease subunit SLX4; Regulatory subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (776 aa)
RVB2RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (498 aa)
HFL1DNA polymerase epsilon noncatalytic subunit. (237 aa)
CaO19.2985Uncharacterized protein. (172 aa)
SFL2Transcription factor SFL2; Transcription factor that plays a role of activator of filamentous growth and which is involved in invasive growth at a high temperature. Required for human oral epithelium colonization and damage. Promotes filamentous growth in EFG1- and FLO8-dependent manners. Antagonizes functions of SFL1. Belongs to the HSF family. (714 aa)
HYS2DNA-directed DNA polymerase delta subunit. (474 aa)
POB3FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (538 aa)
CaO19.1441Uncharacterized protein. (618 aa)
ASK1Ask1p. (594 aa)
CaO19.4615RXT2_N domain-containing protein. (318 aa)
CaO19.5890Uncharacterized protein. (1111 aa)
ARP6Actin-like protein ARP6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (446 aa)
DAM1DASH complex subunit DAM1; Component of the DASH complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The DASH complex mediates the formation and maintenance of bipolar kinetochore-microtubule attachments by forming closed rings around spindle microtubules and establishing interactions with proteins from the central kinetochore (By similarity). (277 aa)
CaO19.4830Uncharacterized protein. (110 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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