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| | HHT21 | Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa) |
| | SIN3 | Transcriptional regulator. (1411 aa) |
| | ARP8 | Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family. (1066 aa) |
| | SIZ1 | SUMO ligase. (1545 aa) |
| | CaO19.4532 | Uncharacterized protein. (354 aa) |
| | CaO19.2964 | Uncharacterized protein. (795 aa) |
| | CaO19.3027 | Uncharacterized protein; Belongs to the actin family. (378 aa) |
| | CaO19.3035 | Chromatin-remodeling ATPase. (1410 aa) |
| | CaO19.3062 | Uncharacterized protein. (1179 aa) |
| | CaO19.4437 | Chromatin-remodeling ATPase. (1017 aa) |
| | CaO19.5069 | Uncharacterized protein. (243 aa) |
| | CaO19.5093 | Uncharacterized protein. (352 aa) |
| | CaO19.4729 | ANK_REP_REGION domain-containing protein. (1381 aa) |
| | SNT1 | Snt1p. (1001 aa) |
| | ROB1 | Rob1p. (991 aa) |
| | SET3 | Histone-binding protein. (1069 aa) |
| | CaO19.7234 | Uncharacterized protein. (561 aa) |
| | DPB4 | DNA polymerase epsilon noncatalytic subunit. (261 aa) |
| | CaO19.2070 | Uncharacterized protein. (568 aa) |
| | NPL6 | Npl6p. (449 aa) |
| | CaO19.2041 | Uncharacterized protein. (636 aa) |
| | CaO19.835 | Uncharacterized protein. (786 aa) |
| | SNF6 | Uncharacterized protein. (505 aa) |
| | CaO19.808 | Rpd3L histone deacetylase complex subunit. (610 aa) |
| | TAF14 | TATA-binding protein-associated factor. (263 aa) |
| | CaO19.4488 | Uncharacterized protein. (971 aa) |
| | CaO19.187 | Uncharacterized protein. (816 aa) |
| | RXT3 | Rxt3p. (517 aa) |
| | CaO19.2265 | SWIB domain-containing protein. (469 aa) |
| | CaO19.2266 | Uncharacterized protein. (830 aa) |
| | CaO19.3625 | Uncharacterized protein. (349 aa) |
| | CaO19.3604 | PAPA-1 domain-containing protein. (382 aa) |
| | SPO11 | Spo11p. (309 aa) |
| | CaO19.1368 | Uncharacterized protein. (607 aa) |
| | PHO23 | Chromatin modification-related protein. (481 aa) |
| | ULP3 | SUMO protease. (874 aa) |
| | HOS2 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (454 aa) |
| | CaO19.1731 | HMG box domain-containing protein. (311 aa) |
| | CaO19.239 | RSC chromatin remodeling complex ATPase subunit. (1302 aa) |
| | CaO19.314 | Uncharacterized protein. (999 aa) |
| | CaO19.6952 | Uncharacterized protein. (669 aa) |
| | SNF5 | Snf5p. (696 aa) |
| | CaO19.4677 | HIT-type domain-containing protein. (236 aa) |
| | CaO19.4639 | Uncharacterized protein. (224 aa) |
| | UME7 | DNA-binding transcriptional regulator. (458 aa) |
| | HOS1 | Histone deacetylase. (436 aa) |
| | AGO1 | Ago1p; Belongs to the argonaute family. (917 aa) |
| | CaO19.2889 | YL1_C domain-containing protein. (137 aa) |
| | CaO19.6667 | SAP30_Sin3_bdg domain-containing protein. (168 aa) |
| | CTA24 | Cta24p. (252 aa) |
| | CaO19.132 | Uncharacterized protein. (593 aa) |
| | CaO19.3399 | YL1_C domain-containing protein. (764 aa) |
| | CaO19.5510 | WAC domain-containing protein. (1272 aa) |
| | CaO19.5555 | Uncharacterized protein. (1131 aa) |
| | CaO19.5617 | PHD domain-containing protein. (479 aa) |
| | CaO19.5620 | Uncharacterized protein. (309 aa) |
| | CaO19.7101 | Telomere_reg-2 domain-containing protein. (788 aa) |
| | YOX1 | Yox1p. (335 aa) |
| | CaO19.7023 | PWWP domain-containing protein. (393 aa) |
| | CaO19.6506 | PHD-type domain-containing protein. (688 aa) |
| | CaO19.5185 | Ran guanyl-nucleotide exchange factor. (492 aa) |
| | HHO1 | Histone. (180 aa) |
| | ZCF29 | Zcf29p. (1105 aa) |
| | UME1 | Ume1p. (485 aa) |
| | CaO19.7506 | Uncharacterized protein. (407 aa) |
| | RPD3 | Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa) |
| | ZCF19 | Zcf19p. (619 aa) |
| | CaO19.1856 | Uncharacterized protein. (340 aa) |
| | CaO19.3890 | DNA-dependent ATPase. (1097 aa) |
| | CaO19.7344 | Uncharacterized protein. (835 aa) |
| | CaO19.7662 | CID domain-containing protein. (335 aa) |
| | CTA26 | Cta26p. (273 aa) |
| | DEF1 | Transcriptional regulator DEF1; Transcriptional regulator involved in extension of germ tubes into elongated hyphae and maintenance of filamentous growth. Regulates expression of UME6. Acts in a pathway that regulates maintenance of hyphal growth by repressing hyphal-to-yeast transition and allows dissemination within host epithelial tissues. Dispensable for invasion into both host oral epithelial cells and enterocytes, but required for epithelial damage. (887 aa) |
| | UBC2 | Ubiquitin-conjugating enzyme E2 2; Catalyzes the covalent attachment of ubiquitin to other proteins. Plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation. Also involved in postreplication repair of UV-damaged DNA, in N-end rule-dependent protein degradation and in sporulation. (179 aa) |
| | COB | Cytochrome b; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex) that is part of the mitochondrial respiratory chain. The b-c1 complex mediates electron transfer from ubiquinol to cytochrome c. Contributes to the generation of a proton gradient across the mitochondrial membrane that is then used for ATP synthesis. (387 aa) |
| | ADF1 | Adherence factor; Surface antigen mediating adhesion and aggregation in S.cerevisiae. (612 aa) |
| | HTB1 | Histone H2B.1; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (130 aa) |
| | SPT6 | Transcription elongation factor SPT6; Plays a role in maintenance of chromatin structure during RNA polymerase II transcription elongation thereby repressing transcription initiation from cryptic promoters. Mediates the reassembly of nucleosomes onto the promoters of at least a selected set of genes during repression; the nucleosome reassembly is essential for transcriptional repression (By similarity); Belongs to the SPT6 family. (1401 aa) |
| | EAF3 | Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (369 aa) |
| | INO80 | Chromatin-remodeling ATPase INO80; ATPase component of the INO80 complex which remodels chromatin by shifting nucleosomes and is involved in DNA repair. (1387 aa) |
| | TLO9 | Tlo9p. (225 aa) |
| | YAF9 | Protein AF-9 homolog; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histones H4 and H2A. The NuA4 complex is also involved in DNA repair. Yaf9 may also be required for viability in conditions in which the structural integrity of the spindle is compromised (By similarity). (254 aa) |
| | CaO19.190 | Uncharacterized protein. (324 aa) |
| | CSE4 | Histone H3-like centromeric protein CSE4; Histone H3-like variant which exclusively replaces conventional H3 in the nucleosome core of centromeric chromatin at the inner plate of the kinetochore. Required for recruitment and assembly of kinetochore proteins, mitotic progression and chromosome segregation. May serve as an epigenetic mark that propagates centromere identity through replication and cell division (By similarity). (211 aa) |
| | UME6 | Transcriptional regulatory protein UME6; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). UME6 controls the level and duration of gene expression in the filamentous growth program such as HGC1; and is specifically important for hyphal elongation and germ tube formation. Promo [...] (843 aa) |
| | HMO1 | Transcriptional regulator HMO1; Transcription factor that binds upstream of hexose and ergosterol metabolism, as well as cell cycle genes. Activates pseudohyphal growth. (223 aa) |
| | HAT2 | Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. (382 aa) |
| | CaO19.6907 | DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (602 aa) |
| | HTA1 | Histone H2A.1; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (132 aa) |
| | CaO19.4544 | Uncharacterized protein. (239 aa) |
| | ZCF3 | Zcf3p. (195 aa) |
| | CaO19.1143 | Uncharacterized protein. (394 aa) |
| | GRC3 | Polynucleotide 5'-hydroxyl-kinase GRC3; Polynucleotide 5'-kinase involved in rRNA processing. Belongs to the Clp1 family. NOL9/GRC3 subfamily. (686 aa) |
| | SWR1 | Helicase SWR1; Catalytic component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling; Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. (1641 aa) |
| | SWI1 | Swi1p. (987 aa) |
| | HHF1 | Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (105 aa) |
| | HTB2 | Histone H2B.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (130 aa) |
| | HTA2 | Histone H2A.2; Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (131 aa) |
| | SET2 | Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (844 aa) |
| | CaO19.3581 | WD_REPEATS_REGION domain-containing protein. (435 aa) |
| | RVB1 | RuvB-like helicase 1; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (458 aa) |
| | VID21 | Chromatin modification-related protein EAF1; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (686 aa) |
| | CDC68 | FACT complex subunit SPT16; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (1060 aa) |
| | SET5 | Potential protein lysine methyltransferase SET5; Putative protein lysine methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET5 subfamily. (473 aa) |
| | ISW2 | ISWI chromatin-remodeling complex ATPase ISW2; Catalytic component of the ISW2 complex, which acts in remodeling the chromatin by catalyzing an ATP-dependent alteration in the structure of nucleosomal DNA. The ISW2 complex is involved in coordinating transcriptional repression and in inheritance of telomeric silencing (By similarity). ISW2 is required for chlamydospore formation, distinctive morphological feature of the fungal pathogen C.albicans that can be induced to form in oxygen-limited environments and has been reported in clinical specimens; Belongs to the SNF2/RAD54 helicase fa [...] (1056 aa) |
| | BRE1 | E3 ubiquitin-protein ligase BRE1; E3 ubiquitin-protein ligase that mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation; Belongs to the BRE1 family. (681 aa) |
| | CaO19.504 | Uncharacterized protein; Belongs to the actin family. (776 aa) |
| | JHD1 | JmjC domain-containing histone demethylation protein 1; Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. (478 aa) |
| | SWC5 | SWR1-complex protein 5; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (338 aa) |
| | HDA1 | Histone deacetylase HDA1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates the YNG2 subunit of NuA4 histone acetyltransferase (HAT) module, leading to the reduction of YNG2 and NuA4 HAT at the promoters of hypha-specific genes. Plays a key role in the regulation o [...] (833 aa) |
| | ARP9 | Arp9p; Belongs to the actin family. (484 aa) |
| | CaO19.2473 | RFX-type winged-helix domain-containing protein. (634 aa) |
| | SWC4 | SWR1-complex protein 4; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (635 aa) |
| | RCA1 | Rca1p. (283 aa) |
| | ASA1 | ASTRA-associated protein 1; Component of the ASTRA complex involved in chromatin remodeling. (377 aa) |
| | ARP4 | Actin-related protein 4; Chromatin interaction component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair. Is required for NuA4 complex integrity. Component of the SWR1 complex which mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Component of the INO80 complex which remodels chromatin by shifting nucleosomes [...] (468 aa) |
| | NDT80 | Transcription factor. (504 aa) |
| | RAD5 | DNA repair protein RAD5; Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs (By similarity). (1084 aa) |
| | SAS2 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (352 aa) |
| | CHL1 | ATP-dependent DNA helicase CHL1; ATP-dependent DNA helicase important for chromosome transmission and normal cell cycle progression in G(2)/M (By similarity). May have a role in changing DNA topology to allow the loading of proteins involved in maintaining sister chromatid cohesion in the vicinity of the centromeres (By similarity). Has a specific role in chromosome segregation during meiosis II (By similarity). (842 aa) |
| | RPD31 | Histone deacetylase. (577 aa) |
| | HHT3 | Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa) |
| | CaO19.340 | ESCRT-I subunit protein. (199 aa) |
| | HTZ1 | Histone H2A.Z; Variant histone H2A which can replace H2A in some nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. This variant is enriched at promoters, it may keep them in a repressed state until the appropriate activa [...] (133 aa) |
| | MAC1 | Metal-binding activator 1; Copper ion-sensing transcription factor which activates transcription of the CTR1 copper transporter under low-copper conditions. Promotes filamentous and invasive growth. (431 aa) |
| | MCM1 | Transcription factor of morphogenesis MCM1; Transcription factor that is recruited by AHR1 to the promoters of genes involved in biofilm formation, which include several key adhesion genes. Plays an important role in cell adhesion, hyphal growth and virulence. Implicated in the regulation of opaque-phase- specific gene expression. (262 aa) |
| | IFH1 | Transcriptional regulator IFH1; In complex with IFH1, acts as a transcriptional regulator of rRNA and ribosomal protein genes. The FHL1-IFH1 complex is targeted to the ribosomal protein genes by the DNA-binding factor TBF1. (885 aa) |
| | RVB2 | RuvB-like helicase 2; DNA helicase which participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes. The SWR1 complex mediates the ATP-dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. The INO80 complex remodels chromatin by shifting nucleosomes and is involved in DNA repair. Also involved in pre-rRNA processing (By similarity); Belongs to the RuvB family. (498 aa) |
| | HFL1 | DNA polymerase epsilon noncatalytic subunit. (237 aa) |
| | CaO19.2985 | Uncharacterized protein. (172 aa) |
| | POB3 | FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...] (538 aa) |
| | CaO19.1441 | Uncharacterized protein. (618 aa) |
| | CaO19.4615 | RXT2_N domain-containing protein. (318 aa) |
| | WOR2 | White-opaque regulator 2; Transcriptional regulator of the switch between 2 heritable states, the white and opaque states. These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence. Each state is heritable for many generations, and switching between states occurs stochastically, at low frequency. WOR2 is necessary for the stability of the opaque state phenotypic switching from the white to the opaque phase is a necessary step for mating. Plays a role in cell adhesion and pseudohyphal growth. (446 aa) |
| | TEC1 | Transcription activator TEC1; Transcription factor which regulates genes involved in hyphal development, cell adhesion, biofilm development, and virulence. Plays a role in the formation of 'finger' morphology, a unique multicellular morphology of C.albicans induced by carbon dioxide. Regulates gene expression during intestinal colonization. Required for the expression of the secreted aspartyl proteinases SAP4, SAP5, and SAP6; but also of BCR1, PGA4, and CDC24. Moreover, a positive feedback loop between CDC24 and TEC1 contributes to an increase in active CDC42 at the tip of the germ tub [...] (743 aa) |
| | CaO19.5890 | Uncharacterized protein. (1111 aa) |
| | ARP6 | Actin-like protein ARP6; Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant HZT1 leading to transcriptional regulation of selected genes by chromatin remodeling. Involved in chromosome stability (By similarity). (446 aa) |
| | WOR1 | White-opaque regulator 1; Master transcriptional regulator of the switch between 2 heritable states, the white and opaque states. These 2 cell types differ in many characteristics, including cell structure, mating competence, and virulence. Each state is heritable for many generations, and switching between states occurs stochastically, at low frequency. WOR1 Binds the intergenic regions upstream of the genes encoding three additional transcriptional regulators of white-opaque switching, CZF1, EFG1, and WOR2. Phenotypic switching from the white to the opaque phase is a necessary step f [...] (785 aa) |
| | SFU1 | Suppressor of ferric uptake 1; Transcriptional regulator of iron-responsive genes. Represses expression of SEF1 and genes for iron uptake if iron is present. Plays also a transcription-independent role in the direct inhibition of SEF1 function through protein complex formation and translocation to the cytoplasm, where SEF1 is destabilized. Promotes gastrointestinal commensalism in mice. (517 aa) |
| | HCM1 | Hcm1p. (579 aa) |
