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| | VPH2 | Vph2p. (213 aa) |
| | CaO19.641 | J domain-containing protein. (300 aa) |
| | CaO19.698 | Uncharacterized protein. (493 aa) |
| | CaO19.916 | Uncharacterized protein; Belongs to the BI1 family. (258 aa) |
| | CaO19.719 | E3 ubiquitin-protein ligase. (633 aa) |
| | ALG6 | Alpha-1,3-glucosyltransferase; Belongs to the ALG6/ALG8 glucosyltransferase family. (563 aa) |
| | FLC2 | Flavin adenine dinucleotide transporter. (811 aa) |
| | EMP46 | Emp46p. (465 aa) |
| | CaO19.6134 | Sec39 domain-containing protein. (817 aa) |
| | CaO19.6117 | Uncharacterized protein. (446 aa) |
| | FGR32 | Fgr32p. (773 aa) |
| | CaO19.7321 | Striatin domain-containing protein. (606 aa) |
| | PHO88 | Pho88p. (191 aa) |
| | CaO19.7329 | E2 ubiquitin-conjugating protein; Belongs to the ubiquitin-conjugating enzyme family. (167 aa) |
| | VMA22 | Vma22p. (188 aa) |
| | CaO19.7670 | Uncharacterized protein; Belongs to the Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family. (923 aa) |
| | CaO19.7672 | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (331 aa) |
| | ERG5 | C-22 sterol desaturase; Belongs to the cytochrome P450 family. (517 aa) |
| | CaO19.5156 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (200 aa) |
| | ERG25 | Methylsterol monooxygenase; Catalyzes the first step in the removal of the two C-4 methyl groups of 4,4-dimethylzymosterol; Belongs to the sterol desaturase family. (308 aa) |
| | PMT1 | Dolichyl-phosphate-mannose--protein mannosyltransferase 1; Protein mannosyltransferase (PMT) involved in hyphal growth and drug sensitivity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Accounts for the O-glycosylation of the cell wall proteins KRE9, PIR2, RHD3, and ALS1, as well as the SEC20 t-SNARE component. O-glycosylation of SEC20 is essential for its stability. Required for filamentatio [...] (877 aa) |
| | GET3 | ATPase GET3; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (350 aa) |
| | GET2 | Golgi to ER traffic protein 2; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP- dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. (298 aa) |
| | CDC28 | Cyclin-dependent kinase 1; Cyclin-dependent kinase essential for the completion of the start, the controlling event, in the cell cycle. Plays a role in the expression of morphology-related transcription factors, and especially hyphae-specific genes. Binds distinct cyclin subunits as cells progress through the division cycle or flamentous growth. The CDC28-CLB2 complex regulates cytokinesis partly by phosphorylating the actomyosin ring component IQG1. The CDC28-CLN3 complex phosphorylates SLA1 which regulates cortical actin patch dynamics. The CDC28-CCN1 complex phosphorylates CDC11 and [...] (317 aa) |
| | CDC25 | Cell division control protein 25; Promotes the exchange of Ras-bound GDP by GTP. This protein positively controls the level of cellular cAMP at start, the stage at which the yeast cell division cycle is triggered. (1333 aa) |
| | ALG2 | Alpha-1,3/1,6-mannosyltransferase ALG2; Mannosylates Man(2)GlcNAc(2)-dolichol diphosphate and Man(1)GlcNAc(2)-dolichol diphosphate to form Man(3)GlcNAc(2)-dolichol diphosphate. (443 aa) |
| | MDM10 | Mitochondrial distribution and morphology protein 10; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis and may function in phospholipid exchange. MDM10 is involved in the late assembly steps of the general translocase of the mitochondrial outer membrane (TOM complex). Functions in the TOM40-specific route of the assembly of outer membrane beta-barrel proteins, including the association of TOM40 with the recepto [...] (473 aa) |
| | CHO2 | Phosphatidylethanolamine N-methyltransferase; Catalyzes the first step of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylethanolamine (PE) to phosphatidylmonomethylethanolamine (PMME); Belongs to the class VI-like SAM-binding methyltransferase superfamily. CHO2 family. (888 aa) |
| | CaO19.3697 | Uncharacterized protein. (993 aa) |
| | EPT1 | Bifunctional diacylglycerol cholinephosphotransferase/ethanolaminephosphotransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (402 aa) |
| | MDM34 | Mitochondrial distribution and morphology protein 34; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM34 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. (623 aa) |
| | CaO19.6284 | Signal recognition particle receptor subunit beta. (305 aa) |
| | SNL1 | Snl1p. (199 aa) |
| | CUE1 | Coupling of ubiquitin conjugation to ER degradation protein 1; Component of the endoplasmic reticulum-associated protein degradation (ERAD) pathway. Recruits the soluble ubiquitin-conjugating enzyme UBC7 to the cytoplasmic face of the endoplasmic reticulum membrane where it functions in degradation of misfolded or regulated proteins localized in the endoplasmic reticulum (ER) lumen or membrane via the ubiquitin-proteasome system. Targets the E2 conjugating enzyme UBC7 to the DOA10 ubiquitin ligase complex, which is part of the ERAD-C pathway responsible for the rapid degradation of mem [...] (189 aa) |
| | CaO19.1412 | Uncharacterized protein. (210 aa) |
| | FEN1 | Elongation of fatty acids protein. (337 aa) |
| | GPI8 | GPI-anchor transamidase; Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein. Belongs to the peptidase C13 family. (383 aa) |
| | SPF1 | Cation-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily. (1223 aa) |
| | ALG1 | Chitobiosyldiphosphodolichol beta-mannosyltransferase; Participates in the formation of the lipid-linked precursor oligosaccharide for N-glycosylation. Involved in assembling the dolichol-pyrophosphate-GlcNAc(2)-Man(5) intermediate on the cytoplasmic surface of the ER (By similarity); Belongs to the glycosyltransferase group 1 family. (456 aa) |
| | ERF2 | Palmitoyltransferase ERF2; The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. (514 aa) |
| | CaO19.6860 | CDP-diacylglycerol--inositol 3-phosphatidyltransferase. (230 aa) |
| | KSR1 | 3-ketodihydrosphingosine reductase TSC10; Catalyzes the reduction of 3-ketodihydrosphingosine (KDS) to dihydrosphingosine (DHS); Belongs to the short-chain dehydrogenases/reductases (SDR) family. (310 aa) |
| | MDM12 | Mitochondrial distribution and morphology protein 12; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. MDM12 is required for the interaction of the ER-resident membrane protein MMM1 and the outer mitochondrial membrane-resident beta-barrel protein MDM10. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pat [...] (428 aa) |
| | ALG11 | GDP-Man:Man(3)GlcNAc(2)-PP-Dol alpha-1,2-mannosyltransferase; Required for N-linked oligosaccharide assembly. Has a role in the last step of the synthesis of the Man(5)GlcNAc(2)-PP-dolichol core oligosaccharide on the cytoplasmic face of the endoplasmic reticulum (By similarity); Belongs to the glycosyltransferase group 1 family. (609 aa) |
| | SAR1 | Small COPII coat GTPase SAR1; Small GTPase component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. SAR1 controls the coat assembly in a stepwise manner. Activated SAR1-GTP binds to membranes first and recruits the SEC23/24 complex. These SEC23/24-SAR1 prebudding intermediates are then collected by the SEC13/31 complex as subunits polymerize to form coated trans [...] (190 aa) |
| | MMM1 | Maintenance of mitochondrial morphology protein 1; Component of the ERMES/MDM complex, which serves as a molecular tether to connect the endoplasmic reticulum (ER) and mitochondria. Components of this complex are involved in the control of mitochondrial shape and protein biogenesis, and function in nonvesicular lipid trafficking between the ER and mitochondria. The MDM12-MMM1 subcomplex functions in the major beta-barrel assembly pathway that is responsible for biogenesis of all outer membrane beta- barrel proteins, and acts in a late step after the SAM complex. The MDM10-MDM12-MMM1 su [...] (439 aa) |
| | SEC72 | Sec63 complex subunit. (204 aa) |
| | CaO19.6941 | Diacylglycerol O-acyltransferase. (577 aa) |
| | CaO19.4528 | Uncharacterized protein. (181 aa) |
| | OSH3 | Oxysterol-binding protein related protein; Belongs to the OSBP family. (844 aa) |
| | CaO19.1158 | Uncharacterized protein. (297 aa) |
| | CaO19.1407 | Uncharacterized protein. (446 aa) |
| | APR1 | Proteinase A; Belongs to the peptidase A1 family. (419 aa) |
| | MNN10 | Alpha-1,6-mannosyltransferase. (335 aa) |
| | EMP24 | Emp24p. (200 aa) |
| | CaO19.3859 | Very-long-chain 3-oxoacyl-CoA reductase; Component of the microsomal membrane bound fatty acid elongation system, which produces the 26-carbon very long-chain fatty acids (VLCFA) from palmitate. Catalyzes the reduction of the 3- ketoacyl-CoA intermediate that is formed in each cycle of fatty acid elongation. VLCFAs serve as precursors for ceramide and sphingolipids. Belongs to the short-chain dehydrogenases/reductases (SDR) family. (349 aa) |
| | ERG3 | C-5 sterol desaturase; Belongs to the sterol desaturase family. (386 aa) |
| | GPI18 | GPI mannosyltransferase 2; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the second mannose to the glycosylphosphatidylinositol during GPI precursor assembly (By similarity). (394 aa) |
| | BST1 | GPI inositol-deacylase; Involved in inositol deacylation of GPI-anchored proteins which plays important roles in the quality control and ER-associated degradation of GPI-anchored proteins. (390 aa) |
| | CWH8 | Cwh8p. (241 aa) |
| | CDC48 | AAA family ATPase; Belongs to the AAA ATPase family. (826 aa) |
| | BIG1 | Protein BIG1; Required for normal beta-1,6-glucan synthesis, for hyphal morphogenesis, adhesion and virulence; Belongs to the BIG1 family. (322 aa) |
| | PMT4 | Dolichyl-phosphate-mannose--protein mannosyltransferase 4; Protein mannosyltransferase (PMT) involved in hyphal growth and drug sensitivity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Accounts for the O-glycosylation of AXL2, responsible for bud site selection, as well as of the SEC20 t-SNARE component. O-glycosylation of SEC20 is essential for its stability. Required for biofilm formation. [...] (755 aa) |
| | DIE2 | Dol-P-Glc:Glc(2)Man(9)GlcNAc(2)-PP-Dol alpha-1,2-glucosyltransferase; Adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(2)Man(9)GlcNAc(2)-PP-Dol; Belongs to the ALG10 glucosyltransferase family. (450 aa) |
| | ARE2 | O-acyltransferase. (609 aa) |
| | CaO19.3558 | GOLD domain-containing protein. (213 aa) |
| | CaO19.5833 | Polyubiquitin-binding protein. (363 aa) |
| | SUR2 | Sphingosine hydroxylase; Belongs to the sterol desaturase family. (342 aa) |
| | SCT2 | Bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase. (718 aa) |
| | SMP3 | GPI mannosyltransferase 4; Alpha-1,2-mannosyltransferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers a fourth mannose to trimannosyl-GPIs during GPI precursor assembly. The presence of a fourth mannose in GPI is essential in fungi (By similarity). Belongs to the glycosyltransferase 22 family. PIGZ subfamily. (498 aa) |
| | CaO19.3135 | UBX domain-containing protein. (593 aa) |
| | CaO19.3132 | Metal cation transporter. (626 aa) |
| | YDC1 | Alkaline dihydroceramidase. (296 aa) |
| | ERG26 | Sterol-4-alpha-carboxylate 3-dehydrogenase (Decarboxylating). (350 aa) |
| | ERF4 | Ras modification protein ERF4; The ERF2-ERF4 complex is a palmitoyltransferase specific for Ras proteins. Palmitoylates RAS2, which is required for its proper plasma membrane localization (By similarity). (218 aa) |
| | PEX19 | Pex19p. (332 aa) |
| | CaO19.6416 | Uncharacterized protein. (465 aa) |
| | SIL1 | Nucleotide exchange factor SIL1; Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity). (414 aa) |
| | NTE1 | Lysophospholipase NTE1; Intracellular phospholipase B that catalyzes the double deacylation of phosphatidylcholine (PC) to glycerophosphocholine (GroPCho). Plays an important role in membrane lipid homeostasis. Responsible for the rapid PC turnover in response to inositol, elevated temperatures, or when choline is present in the growth medium (By similarity); Belongs to the NTE family. (1386 aa) |
| | CaO19.6379 | Uncharacterized protein. (152 aa) |
| | MCD4 | GPI ethanolamine phosphate transferase 1; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the first alpha-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor (By similarity). (971 aa) |
| | SEC23 | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (762 aa) |
| | PBN1 | Protein PBN1; Required for proper folding and/or the stability of a subset of proteins in the endoplasmic reticulum. Component of glycosylphosphatidylinositol-mannosyltransferase 1 which transfers the first of the 4 mannoses in the GPI-anchor precursors during GPI-anchor biosynthesis. Probably acts by stabilizing the mannosyltransferase GPI14 (By similarity). (481 aa) |
| | ROT2 | Glucan 1-alpha-glucosidase ROT2; Belongs to the glycosyl hydrolase 31 family. (871 aa) |
| | ECM39 | Mannosyltransferase. (584 aa) |
| | ALG14 | UDP-N-acetylglucosamine transferase subunit ALG14; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway. Anchors the catalytic subunit ALG13 to the ER (By similarity). (219 aa) |
| | MRP8 | Mrp8p. (205 aa) |
| | CaO19.3843 | Sec63 complex subunit. (268 aa) |
| | SCS7 | Ceramide very long chain fatty acid hydroxylase; Ceramide hydroxylase involved in the hydroxylation of sphingolipid-associated very long chain fatty acids. Postulated to hydroxylate the very long chain fatty acid of dihydroceramides and phytoceramides at C-2; Belongs to the sterol desaturase family. SCS7 subfamily. (378 aa) |
| | PMT6 | Dolichyl-phosphate-mannose--protein mannosyltransferase 6; Protein mannosyltransferase (PMT) involved in hyphal morphogenesis and drug sensitivity. Transfers mannose from Dol-P- mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Required for biofilm formation and virulence. (832 aa) |
| | DIT2 | Putative cytochrome; Belongs to the cytochrome P450 family. (387 aa) |
| | OLE1 | Acyl-CoA desaturase; Stearyl-CoA desaturase that utilizes O(2) and electrons from reduced cytochrome b5 to introduce the first double bond into saturated fatty acyl-CoA substrates. (486 aa) |
| | CaO19.5418 | Uncharacterized protein. (477 aa) |
| | SWF1 | Palmitoyltransferase SWF1; Palmitoyltransferase that targets several endosomal SNAREs. Palmitoylates the SNAREs at cysteine residues close to the cytoplasmic end of their transmembrane domain. May have a role in the cellular quality control of transmembrane domain-containing proteins (By similarity); Belongs to the DHHC palmitoyltransferase family. SWF1 subfamily. (353 aa) |
| | LAG1 | Sphingosine N-acyltransferase. (412 aa) |
| | CaO19.3329 | Sphinganine kinase. (491 aa) |
| | CaO19.3307 | N,N-dimethylaniline monooxygenase; Belongs to the FMO family. (463 aa) |
| | CHS7 | Chitin synthase export chaperone; Chaperone required for the export of the chitin synthase CHS3 from the endoplasmic reticulum. (310 aa) |
| | PGA63 | Protein transport protein SEC31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1265 aa) |
| | PSD1 | Phosphatidylserine decarboxylase proenzyme 1, mitochondrial; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). Plays a central role in phospholipid metabolism and in the interorganelle trafficking of phosphatidylserine (By similarity). Important for virulence. (590 aa) |
| | ALG13 | UDP-N-acetylglucosamine transferase subunit ALG13; Involved in protein N-glycosylation. Essential for the second step of the dolichol-linked oligosaccharide pathway (By similarity). Belongs to the glycosyltransferase 28 family. (293 aa) |
| | ROT1 | Protein ROT1; Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies (By similarity); Belongs to the ROT1 family. (260 aa) |
| | BMT4 | Beta-mannosyltransferase 4; Beta-mannosyltransferase involved in cell wall biosynthesis. Required for the elongation of beta-mannose chains on the acid-labile fraction of cell wall phosphopeptidomannan. Belongs to the BMT family. (781 aa) |
| | YOS9 | Protein OS-9 homolog; Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation (By similarity). (258 aa) |
| | PMT5 | Dolichyl-phosphate-mannose--protein mannosyltransferase 5; Protein mannosyltransferase (PMT) involved in hyphal morphogenesis and drug sensitivity. Transfers mannose from Dol-P- mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Required for biofilm formation. (725 aa) |
| | GET1 | Golgi to ER traffic protein 1; Required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP- dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER. (199 aa) |
| | CaO19.2045 | Diacylglycerol kinase. (345 aa) |
| | ERG28 | Erg28p. (138 aa) |
| | PMT2 | Dolichyl-phosphate-mannose--protein mannosyltransferase 2; Protein mannosyltransferase (PMT) involved in hyphal growth and drug sensitivity. Transfers mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT1, PMT2 and PMT4 account for most of the protein-O-glycosylation activity, while PMT5 and PMT6 may specifically modulate a much narrower spectrum of target proteins. Essential protein that plays an important role in virulence. Belongs to the glycosyltransferase 39 family. (769 aa) |
| | CaO19.351 | Uncharacterized protein. (155 aa) |
| | SLC1 | 1-acyl-sn-glycerol-3-phosphate acyltransferase; Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. (293 aa) |
| | GPI11 | Glycosylphosphatidylinositol anchor biosynthesis protein 11; Acts in the GPI biosynthetic pathway between GlcNAc-PI synthesis and GPI transfer to protein. (265 aa) |
| | CaO19.4240 | Post-GPI attachment to proteins factor 3; Involved in the lipid remodeling steps of GPI-anchor maturation; Belongs to the PGAP3 family. (394 aa) |
| | PFA4 | Palmitoyltransferase PFA4; Mediates the reversible addition of palmitate to target proteins, thereby regulating their membrane association and biological function; Belongs to the DHHC palmitoyltransferase family. PFA4 subfamily. (446 aa) |
| | CaO19.6558 | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (815 aa) |
| | CaO19.6552 | Sulfhydryl oxidase. (254 aa) |
| | CaO19.3060 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (275 aa) |
| | SEC62 | Translocation protein SEC62; Required for preprotein translocation. (293 aa) |
| | ALG8 | Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase; Adds the second glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc(1)Man(9)GlcNAc(2)-PP-Dol (By similarity). Belongs to the ALG6/ALG8 glucosyltransferase family. (587 aa) |
| | CaO19.1653 | Uncharacterized protein. (196 aa) |
| | GPI10 | GPI mannosyltransferase 3; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the third mannose to Man2-GlcN-acyl-PI during GPI precursor assembly (By similarity). (482 aa) |
| | CaO19.3994 | Dolichyl-diphosphooligosaccharide--protein glycotransferase. (396 aa) |
| | TIP1 | Protein YIP. (251 aa) |
| | STT3 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit. (751 aa) |
| | AGP2 | Agp2p. (568 aa) |
| | GPI14 | GPI mannosyltransferase 1; Mannosyltransferase involved in glycosylphosphatidylinositol- anchor biosynthesis. Transfers the first alpha-1,4-mannose to GlcN- acyl-PI during GPI precursor assembly. Required for cell wall integrity (By similarity). (398 aa) |
| | ERV29 | Erv29p. (308 aa) |
| | CaO19.4566 | Protein ROT1; Required for normal levels of the cell wall 1,6-beta-glucan. Involved in a protein folding machinery chaperoning proteins acting in various physiological processes including cell wall synthesis and lysis of autophagic bodies; Belongs to the ROT1 family. (193 aa) |
| | CaO19.6007 | Elongation of fatty acids protein. (353 aa) |
| | CaO19.5934 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (629 aa) |
| | ARV1 | Protein ARV1; Mediator of sterol homeostasis involved in sterol uptake, trafficking and distribution into membranes. Regulates also the sphingolipid metabolism. Required for growth during anaerobiosis and sterol uptake. Plays a role in pathogenesis. (296 aa) |
| | CaO19.5857 | Zinc_ribbon_10 domain-containing protein. (344 aa) |
| | CaO19.4905 | Uncharacterized protein. (517 aa) |
| | SFH5 | Phosphatidylinositol transfer protein SFH5; Non-classical phosphatidylinositol (PtdIns) transfer protein (PITP), which exhibits PtdIns-binding/transfer activity in the absence of detectable PtdCho-binding/transfer activity. Regulates PtdIns(4,5)P2 homeostasis at the plasma membrane (By similarity); Belongs to the SFH5 family. (320 aa) |
| | CaO19.4738 | SUN domain-containing protein. (558 aa) |
| | SEC24 | Protein transport protein SEC24; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (928 aa) |
| | GWT1 | GPI-anchored wall transfer protein 1; Probable acetyltransferase, which acetylates the inositol ring of phosphatidylinositol during biosynthesis of GPI-anchor. (485 aa) |
| | GPI7 | GPI ethanolamine phosphate transferase 2; Ethanolamine phosphate transferase involved in glycosylphosphatidylinositol-anchor biosynthesis. Transfers ethanolamine phosphate to the GPI second mannose (By similarity). Belongs to the PIGG/PIGN/PIGO family. PIGG subfamily. (885 aa) |
| | ERG1 | Squalene monooxygenase; Catalyzes the stereospecific oxidation of squalene to (S)- 2,3-epoxysqualene, and is considered to be a rate-limiting enzyme in steroid biosynthesis. (496 aa) |
| | SEY1 | Protein SEY1; Cooperates with the reticulon proteins and tubule-shaping DP1 family proteins to generate and maintain the structure of the tubular endoplasmic reticulum network. Has GTPase activity, which is required for its function in ER organization (By similarity). Required for virulence and resistance to cycloheximide; Belongs to the TRAFAC class dynamin-like GTPase superfamily. GB1/RHD3-type GTPase family. RHD3 subfamily. (790 aa) |
| | SEC61 | Protein transport protein SEC61 subunit alpha; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to SEC62/63 complex, secretory precursor polypeptides may engage SEC61 to begin membrane penetration event. A cycle of assembly and disassembly of SEC62/63 from SEC61 may govern the activity of the translocase (By similarity). (479 aa) |
| | OBPA | Oxysterol-binding protein-like protein OBPa. (433 aa) |
| | CaO19.6787 | Cornichon family protein. (137 aa) |
| | CaO19.7426 | Dolichyl-diphosphooligosaccharide--protein glycotransferase. (340 aa) |
| | OPI3 | Phosphatidyl-N-methylethanolamine N-methyltransferase; Catalyzes the second two steps of the methylation pathway of phosphatidylcholine biosynthesis, the SAM-dependent methylation of phosphatidylmonomethylethanolamine (PMME) to phosphatidyldimethylethanolamine (PDME) and of PDME to phosphatidylcholine (PC). (225 aa) |
| | A0A1D8PKK1 | Translocon subunit. (68 aa) |
| | CaO19.7347 | E2 ubiquitin-conjugating protein. (243 aa) |
| | UBP1 | Ubiquitin carboxyl-terminal hydrolase. (804 aa) |
| | GPI1 | Phosphatidylinositol N-acetylglucosaminyltransferase. (648 aa) |
| | CaO19.7364 | Uncharacterized protein; Belongs to the FMO family. (536 aa) |
| | LAC1 | Lac1p. (427 aa) |
| | GTT1 | Gtt1p; Belongs to the GST superfamily. (267 aa) |
| | OST1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...] (470 aa) |
| | GTT12 | Bifunctional glutathione transferase/peroxidase; Belongs to the GST superfamily. (249 aa) |
| | GTT11 | Gtt11p; Belongs to the GST superfamily. (249 aa) |
| | CaO19.6951 | Sphinganine-1-phosphate aldolase. (589 aa) |
| | GTT13 | Gtt13p; Belongs to the GST superfamily. (263 aa) |
| | KRE5 | Kre5p. (1447 aa) |
| | CaO19.323 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1479 aa) |
| | NSG2 | Uncharacterized protein. (334 aa) |
| | YSY6 | Stress-associated endoplasmic reticulum protein; May interact with target proteins during translocation into the lumen of the endoplasmic reticulum. May protect unfolded target proteins against degradation and facilitate correct glycosylation. Belongs to the RAMP4 family. (62 aa) |
| | CaO19.261 | Dolichol kinase. (586 aa) |
| | CaO19.1638 | Protein transport protein SEC23; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules; Belongs to the SEC23/SEC24 family. SEC23 subfamily. (861 aa) |
| | CaO19.1654 | Uncharacterized protein. (195 aa) |
| | SCT1 | Bifunctional glycerol-3-phosphate/glycerone-phosphate O-acyltransferase. (770 aa) |
| | CaO19.2516 | Thioredoxin domain-containing protein. (238 aa) |
| | ERG4 | Delta(24(24(1)))-sterol reductase. (469 aa) |
| | A0A1D8PIU6 | Uncharacterized protein. (82 aa) |
| | CaO19.1761 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit OST2; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (171 aa) |
| | SPT23 | Protein phosphatase; Belongs to the PP2C family. (742 aa) |
| | CaO19.1392 | Protein disulfide isomerase. (737 aa) |
| | ERG24 | Delta(14)-sterol reductase. (448 aa) |
| | DFG10 | Putative polyprenol reductase. (282 aa) |
| | JEM1 | Jem1p. (636 aa) |
| | ERG9 | Bifunctional farnesyl-diphosphate farnesyltransferase/squalene synthase. (448 aa) |
| | ALG7 | UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase. (494 aa) |
| | FLC3 | Flc3p. (718 aa) |
| | PHO86 | Pho86p. (335 aa) |
| | CaO19.2204 | Uncharacterized protein. (368 aa) |
| | LPT1 | Lysophospholipid acyltransferase; Belongs to the membrane-bound acyltransferase family. (602 aa) |
| | CaO19.2257 | Uncharacterized protein. (367 aa) |
| | CaO19.6888 | Zn(2)-C6 fungal-type domain-containing protein. (442 aa) |
| | GPI19 | Phosphatidylinositol N-acetylglucosaminyltransferase. (298 aa) |
| | CaO19.834 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (842 aa) |
| | GPI13 | Mannose-ethanolamine phosphotransferase. (1014 aa) |
| | CaO19.867 | Putative metalloreductase. (537 aa) |
| | CaO19.880 | Uncharacterized protein. (1011 aa) |
| | FEN12 | Elongation of fatty acids protein. (292 aa) |
| | LHS1 | Hsp70 family chaperone. (932 aa) |
| | A0A1D8PGP8 | Uncharacterized protein. (96 aa) |
| | ZRT2 | Low-affinity Zn(2+) transporter. (370 aa) |
| | CaO19.1564 | Bap31 domain-containing protein. (189 aa) |
| | OPI1 | Transcriptional regulator. (432 aa) |
| | CaO19.1534 | Zn(2+) transporter. (591 aa) |
| | CaO19.2001 | Fe2OG dioxygenase domain-containing protein. (251 aa) |
| | KAR2 | Hsp70 family ATPase; Belongs to the heat shock protein 70 family. (687 aa) |
| | WSC4 | Wsc4p. (491 aa) |
| | NCR1 | Sphingolipid transporter. (1256 aa) |
| | CaO19.1160 | Uncharacterized protein. (215 aa) |
| | ERP5 | Erp5p. (218 aa) |
| | WBP1 | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit WBP1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the [...] (437 aa) |
| | CaO19.1840 | Tricalbin. (1228 aa) |
| | SAC1 | Phosphatidylinositol-3-phosphatase. (618 aa) |
| | CaO19.4903 | N-acetylglucosaminylphosphatidylinositol deacetylase. (354 aa) |
| | CaO19.4787 | J domain-containing protein. (730 aa) |
| | DPM1 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (239 aa) |
| | CaO19.5095 | Oxysterol-binding protein related protein; Belongs to the OSBP family. (1318 aa) |
| | IST2 | Ist2p. (953 aa) |
| | CaO19.4423 | VASt domain-containing protein. (1073 aa) |
| | A0A1D8PDT9 | PRA1 family protein. (175 aa) |
| | SSH1 | Ssh1p; Belongs to the SecY/SEC61-alpha family. (499 aa) |
| | CaO19.1043 | Lysophosphatidic acid acyltransferase. (305 aa) |
| | HMG1 | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (1073 aa) |
| | MNS1 | alpha-1,2-Mannosidase; Belongs to the glycosyl hydrolase 47 family. (615 aa) |
| | CaO19.1034 | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. (183 aa) |
| | CaO19.3057 | Uncharacterized protein. (136 aa) |
| | CaO19.3047 | Uncharacterized protein. (1209 aa) |
| | CaO19.3003 | Uncharacterized protein. (1417 aa) |
| | CaO19.4525 | Uncharacterized protein. (333 aa) |
| | CaO19.3351 | Protein YOP1. (291 aa) |
| | CaO19.3293 | Trans-2-enoyl-CoA reductase (NADPH). (312 aa) |
| | ERG2 | C-8 sterol isomerase. (217 aa) |
| | LRO1 | Phospholipid:diacylglycerol acyltransferase. (698 aa) |
| | CaO19.6082 | Uncharacterized protein. (384 aa) |
| | SEC63 | Protein-transporting protein. (673 aa) |
| | CaO19.474 | Brr6_like_C_C domain-containing protein. (433 aa) |
| | ALG5 | Dolichyl-phosphate beta-glucosyltransferase. (323 aa) |
| | A0A1D8PRY9 | Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum. (95 aa) |
| | CWH43 | Cwh43p. (1022 aa) |
| | CaO19.3286 | Uncharacterized protein. (427 aa) |
| | CaO19.7140 | Uncharacterized protein. (248 aa) |
| | UFE1 | Ufe1p. (306 aa) |
| | CaO19.7173 | Uncharacterized protein. (573 aa) |
| | HLJ1 | Type I HSP40 co-chaperone. (331 aa) |
| | PDI1 | Protein disulfide isomerase. (559 aa) |
| | CYR1 | Adenylate cyclase. (1690 aa) |
| | CaO19.5175 | E3 ubiquitin-protein ligase. (1139 aa) |
| | LPI9 | Protein phosphatase regulator. (1364 aa) |
| | CYB5 | Cyb5p; Belongs to the cytochrome b5 family. (126 aa) |
| | CaO19.7043 | Uncharacterized membrane protein. (169 aa) |
| | CaO19.7078 | Uncharacterized protein. (153 aa) |
| | CaO19.1092 | Dol-P-Man:Man(5)GlcNAc(2)-PP-Dol alpha-1,3-mannosyltransferase; Adds the first Dol-P-Man derived mannose in an alpha-1,3 linkage to Man(5)GlcNAc(2)-PP-Dol. (519 aa) |
| | PEX11 | Pex11p. (245 aa) |
| | SEC20 | Sec20p. (332 aa) |
| | ZCF18 | Zcf18p. (510 aa) |
| | SEC12 | Sec12p. (841 aa) |
| | FGR47 | Fgr47p. (974 aa) |
| | CaO19.3438 | Uncharacterized protein. (384 aa) |
| | CaO19.120 | Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (257 aa) |
| | CaO19.119 | Protein-S-isoprenylcysteine O-methyltransferase; Belongs to the class VI-like SAM-binding methyltransferase superfamily. Isoprenylcysteine carboxyl methyltransferase family. (265 aa) |
| | CaO19.90 | VASt domain-containing protein. (754 aa) |
| | SLY41 | Sly41p. (523 aa) |
| | CaO19.3658 | Uncharacterized protein. (647 aa) |
| | CaO19.1191 | Ubiquitin ligase complex subunit. (806 aa) |
| | CaO19.4014 | Metallophos domain-containing protein. (482 aa) |
| | TIP20 | Tip20p. (784 aa) |
| | DUN1 | Serine/threonine protein kinase. (530 aa) |
| | SRP101 | Signal recognition particle receptor subunit alpha. (535 aa) |
| | CaO19.3949 | Bromo domain-containing protein. (1314 aa) |
| | A0A1D8PNY0 | Uncharacterized protein. (89 aa) |
| | CaO19.3920 | Protein disulfide isomerase. (299 aa) |
| | CaO19.1285 | SMP-LTD domain-containing protein. (931 aa) |
| | MID1 | Mid1p. (559 aa) |
| | CaO19.4346 | Protein transport protein sec16; Involved in the initiation of assembly of the COPII coat required for the formation of transport vesicles from the endoplasmic reticulum (ER) and the selection of cargo molecules. Also involved in autophagy; Belongs to the SEC16 family. (2091 aa) |
| | CaO19.4341 | GPI-anchor transamidase subunit. (482 aa) |
| | CaO19.4247 | Derlin; May be involved in the degradation of misfolded endoplasmic reticulum (ER) luminal proteins; Belongs to the derlin family. (315 aa) |
| | CaO19.3180 | Phosphoinositide 5-phosphatase. (457 aa) |
| | CaO19.4141 | Aa_trans domain-containing protein. (502 aa) |
| | CaO19.932 | Phospholipid-transporting ATPase; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily. (1716 aa) |
| | CaO19.5683 | Uncharacterized protein. (138 aa) |
| | CaO19.5693 | GPI-anchor transamidase subunit. (547 aa) |
| | CaO19.3083 | Putative lipid phosphatase. (400 aa) |
| | CaO19.3128 | Syntaxin-binding protein; Belongs to the STXBP/unc-18/SEC1 family. (640 aa) |
| | CSO99 | Cso99p. (330 aa) |
| | CaO19.3769 | Zn(2+) transporter. (687 aa) |
| | CaO19.3804 | Uncharacterized protein. (255 aa) |
| | RCE1 | CAAX prenyl protease. (281 aa) |
| | CaO19.5291 | Uncharacterized protein. (320 aa) |
| | CaO19.5300 | Calnexin. (581 aa) |
| | CSH3 | Csh3p. (236 aa) |
| | CaO19.2677 | GPI-anchor transamidase subunit. (621 aa) |
| | CaO19.2757 | Thioredoxin domain-containing protein. (332 aa) |
| | ERG251 | Erg251p; Belongs to the sterol desaturase family. (321 aa) |
| | STE24 | CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (445 aa) |
| | CaO19.7441 | Brr6_like_C_C domain-containing protein. (308 aa) |
