20 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	RXT3	Rxt3p. (517 aa)
	PHO23	Chromatin modification-related protein. (481 aa)
	CaO19.314	Uncharacterized protein. (999 aa)
	CaO19.4639	Uncharacterized protein. (224 aa)
	UME7	DNA-binding transcriptional regulator. (458 aa)
	CaO19.6667	SAP30_Sin3_bdg domain-containing protein. (168 aa)
	CaO19.5617	PHD domain-containing protein. (479 aa)
	CaO19.6506	PHD-type domain-containing protein. (688 aa)
	UME1	Ume1p. (485 aa)
	CaO19.1856	Uncharacterized protein. (340 aa)
	EAF3	Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). (369 aa)
	UME6	Transcriptional regulatory protein UME6; Component of the RPD3C(L) histone deacetylase complex (HDAC) responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events (By similarity). UME6 controls the level and duration of gene expression in the filamentous growth program such as HGC1; and is specifically important for hyphal elongation and germ tube formation. Promo [...] (843 aa)
	HAT2	Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. (382 aa)
	CaO19.4615	RXT2_N domain-containing protein. (318 aa)
	CaO19.3581	WD_REPEATS_REGION domain-containing protein. (435 aa)
	SET2	Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (844 aa)
	ZCF3	Zcf3p. (195 aa)
	SIN3	Transcriptional regulator. (1411 aa)
	CaO19.808	Rpd3L histone deacetylase complex subunit. (610 aa)
	CaO19.3625	Uncharacterized protein. (349 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CaO19.1856	CaO19.314	A0A1D8PTA8	A0A1D8PJL2	Uncharacterized protein.	Uncharacterized protein.	0.540
CaO19.1856	CaO19.3581	A0A1D8PTA8	Q59ZD9	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.902
CaO19.1856	CaO19.3625	A0A1D8PTA8	A0A1D8PIA8	Uncharacterized protein.	Uncharacterized protein.	0.681
CaO19.1856	CaO19.4615	A0A1D8PTA8	Q5AMN1	Uncharacterized protein.	RXT2_N domain-containing protein.	0.891
CaO19.1856	CaO19.4639	A0A1D8PTA8	A0A1D8PLE6	Uncharacterized protein.	Uncharacterized protein.	0.811
CaO19.1856	CaO19.5617	A0A1D8PTA8	A0A1D8PQ51	Uncharacterized protein.	PHD domain-containing protein.	0.883
CaO19.1856	CaO19.6506	A0A1D8PTA8	A0A1D8PR21	Uncharacterized protein.	PHD-type domain-containing protein.	0.817
CaO19.1856	CaO19.6667	A0A1D8PTA8	A0A1D8PNP8	Uncharacterized protein.	SAP30_Sin3_bdg domain-containing protein.	0.810
CaO19.1856	CaO19.808	A0A1D8PTA8	A0A1D8PH30	Uncharacterized protein.	Rpd3L histone deacetylase complex subunit.	0.540
CaO19.1856	EAF3	A0A1D8PTA8	Q59K07	Uncharacterized protein.	Chromatin modification-related protein EAF3; Involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains. Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity).	0.936
CaO19.1856	HAT2	A0A1D8PTA8	Q59RH5	Uncharacterized protein.	Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing.	0.902
CaO19.1856	PHO23	A0A1D8PTA8	A0A1D8PIP3	Uncharacterized protein.	Chromatin modification-related protein.	0.702
CaO19.1856	RXT3	A0A1D8PTA8	A0A1D8PHC7	Uncharacterized protein.	Rxt3p.	0.698
CaO19.1856	SIN3	A0A1D8PTA8	A0A1D8PCC3	Uncharacterized protein.	Transcriptional regulator.	0.941
CaO19.1856	UME1	A0A1D8PTA8	A0A1D8PRH3	Uncharacterized protein.	Ume1p.	0.902
CaO19.314	CaO19.1856	A0A1D8PJL2	A0A1D8PTA8	Uncharacterized protein.	Uncharacterized protein.	0.540
CaO19.314	CaO19.3581	A0A1D8PJL2	Q59ZD9	Uncharacterized protein.	WD_REPEATS_REGION domain-containing protein.	0.580
CaO19.314	CaO19.3625	A0A1D8PJL2	A0A1D8PIA8	Uncharacterized protein.	Uncharacterized protein.	0.549
CaO19.314	CaO19.4615	A0A1D8PJL2	Q5AMN1	Uncharacterized protein.	RXT2_N domain-containing protein.	0.604
CaO19.314	CaO19.5617	A0A1D8PJL2	A0A1D8PQ51	Uncharacterized protein.	PHD domain-containing protein.	0.548