STRINGSTRING
CaO19.4029 CaO19.4029 CAC2 CAC2 CaO19.4325 CaO19.4325 CaO19.4312 CaO19.4312 UTP13 UTP13 CaO19.1791 CaO19.1791 CaO19.3779 CaO19.3779 CaO19.2711 CaO19.2711 PWP1 PWP1 CaO19.5954 CaO19.5954 CaO19.268 CaO19.268 UTP4 UTP4 CaO19.1672 CaO19.1672 VPS8 VPS8 CaO19.2191 CaO19.2191 STE4 STE4 UTP21 UTP21 CaO19.7235 CaO19.7235 CaO19.4913 CaO19.4913 CaO19.6347 CaO19.6347 CaO19.6355 CaO19.6355 DOA1 DOA1 CaO19.384 CaO19.384 CaO19.2455 CaO19.2455 BPH1 BPH1 YTM1 YTM1 CaO19.4835 CaO19.4835 CDC55 CDC55 TIF34 TIF34 ATG21 ATG21 TRM82 TRM82 HIR2 HIR2 CIA1 CIA1 NAN1 NAN1 SEC13 SEC13 CDH1 CDH1 HIR1 HIR1 RTC1 RTC1 ASA1 ASA1 ATG18 ATG18 IPI3 IPI3 PGA63 PGA63 CaO19.2527 CaO19.2527 CDC4 CDC4 CaO19.3301 CaO19.3301 SKI8 SKI8 CaO19.3241 CaO19.3241 PWP2 PWP2 SWD1 SWD1 SOF1 SOF1 PAC1 PAC1 PRP46 PRP46 DIP2 DIP2 SEH1 SEH1 KOG1 KOG1 RRP9 RRP9 CaO19.3581 CaO19.3581 UTP15 UTP15 DSE1 DSE1 CaO19.587 CaO19.587 PEX7 PEX7 PFS2 PFS2 ERB1 ERB1 CaO19.3862 CaO19.3862 CaO19.6907 CaO19.6907 SRO77 SRO77 HAT2 HAT2 BUB3 BUB3 SWD2 SWD2 HSV2 HSV2 ASC1 ASC1 TUP1 TUP1 CaO19.7343 CaO19.7343 ARC40 ARC40 CaO19.536 CaO19.536 CaO19.4395 CaO19.4395 CaO19.7527 CaO19.7527 UTP18 UTP18 UME1 UME1 ENP2 ENP2 CaO19.5131 CaO19.5131 CRN1 CRN1 CaO19.2143 CaO19.2143 GLE2 GLE2 SEC27 SEC27 SWD3 SWD3 CDC20 CDC20 VPS15 VPS15 CaO19.132 CaO19.132
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CaO19.4029WD_REPEATS_REGION domain-containing protein. (415 aa)
CAC2Cac2p. (460 aa)
CaO19.4325Uncharacterized protein. (1143 aa)
CaO19.4312SAGA complex subunit. (770 aa)
UTP13Utp13p. (799 aa)
CaO19.1791Uncharacterized protein. (491 aa)
CaO19.3779WD_REPEATS_REGION domain-containing protein. (519 aa)
CaO19.2711Elongator subunit. (797 aa)
PWP1rRNA-processing protein. (613 aa)
CaO19.5954WD_REPEATS_REGION domain-containing protein. (510 aa)
CaO19.268Uncharacterized protein. (447 aa)
UTP4Utp4p. (743 aa)
CaO19.1672Coatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1221 aa)
VPS8CORVET complex membrane-binding subunit. (1346 aa)
CaO19.2191Diphthamide synthase. (345 aa)
STE4G protein subunit beta. (457 aa)
UTP21rRNA-processing protein. (942 aa)
CaO19.7235Uncharacterized protein. (892 aa)
CaO19.4913WD_REPEATS_REGION domain-containing protein. (1208 aa)
CaO19.6347WD_REPEATS_REGION domain-containing protein. (520 aa)
CaO19.6355Ribosome biosynthesis protein. (517 aa)
DOA1Doa1p. (761 aa)
CaO19.384Uncharacterized protein. (558 aa)
CaO19.2455Glutamine amidotransferase subunit. (1131 aa)
BPH1Bph1p. (2273 aa)
YTM1Ribosome biogenesis protein YTM1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (466 aa)
CaO19.4835WD_REPEATS_REGION domain-containing protein. (527 aa)
CDC55Protein phosphatase PP2A regulatory subunit B; Belongs to the phosphatase 2A regulatory subunit B family. (519 aa)
TIF34Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (350 aa)
ATG21Autophagy-related protein 21; Required for cytoplasm to vacuole transport (Cvt) vesicles formation and mitophagy. Involved in binding of phosphatidylethanolamine to ATG8 and in recruitment of ATG8 and ATG5 to the pre-autophagosomal structure. Protects ATG8 from ARG4-mediated cleavage (By similarity); Belongs to the WD repeat SVP1 family. (529 aa)
TRM82tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit TRM82; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. (426 aa)
HIR2Protein HIR2; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (1017 aa)
CIA1Probable cytosolic iron-sulfur protein assembly protein 1; Essential component of the cytosolic iron-sulfur (Fe/S) protein assembly machinery. Required for the maturation of extramitochondrial Fe/S proteins. (383 aa)
NAN1Nan1p. (839 aa)
SEC13Protein transport protein SEC13; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules. It also functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport facto [...] (298 aa)
CDH1Cdh1p. (597 aa)
HIR1Protein HIR1; Required for replication-independent chromatin assembly and for the periodic repression of histone gene transcription during the cell cycle; Belongs to the WD repeat HIR1 family. (907 aa)
RTC1Restriction of telomere capping protein 1; May be involved in a process influencing telomere capping. Belongs to the WD repeat RTC1 family. (1088 aa)
ASA1ASTRA-associated protein 1; Component of the ASTRA complex involved in chromatin remodeling. (377 aa)
ATG18Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct ATG9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity). (558 aa)
IPI3Pre-rRNA-processing protein IPI3; Component of the RIX1 complex required for processing of ITS2 sequences from 35S pre-rRNA. (505 aa)
PGA63Protein transport protein SEC31; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules (By similarity). (1265 aa)
CaO19.2527WD_REPEATS_REGION domain-containing protein. (428 aa)
CDC4SCF ubiquitin ligase complex subunit. (768 aa)
CaO19.3301Ubiquitin-binding SDF ubiquitin ligase complex subunit. (735 aa)
SKI8SKI complex subunit WD repeat protein. (384 aa)
CaO19.3241WD_REPEATS_REGION domain-containing protein. (1417 aa)
PWP2SnoRNA-binding rRNA-processing protein. (922 aa)
SWD1COMPASS subunit protein. (447 aa)
SOF1rRNA-processing protein. (436 aa)
PAC1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein- mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck. (486 aa)
PRP46Pre-mRNA-splicing factor PRP46; Involved in pre-mRNA splicing and required for cell cycle progression at G2/M. (389 aa)
DIP2SnoRNA-binding rRNA-processing protein. (981 aa)
SEH1Seh1p; Belongs to the WD repeat SEC13 family. (347 aa)
KOG1Ubiquitin-binding TORC1 subunit. (1432 aa)
RRP9Rrp9p. (549 aa)
CaO19.3581WD_REPEATS_REGION domain-containing protein. (435 aa)
UTP15SnoRNA-binding rRNA-processing protein. (423 aa)
DSE1Protein DSE1; Involved in cell wall metabolism and required for the separation of the mother and daughter cells. (724 aa)
CaO19.587WD_REPEATS_REGION domain-containing protein. (397 aa)
PEX7Pex7p. (380 aa)
PFS2Polyadenylation factor subunit 2; Required for 3'-end cleavage and polyadenylation of pre- mRNAs. Also involved in chromosome segregation where it has a role in chromosome attachment to the mitotic spindle (By similarity). (543 aa)
ERB1Ribosome biogenesis protein ERB1; Component of the NOP7 complex, which is required for maturation of the 25S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (849 aa)
CaO19.3862TOR complex subunit. (328 aa)
CaO19.6907DNA damage-binding protein CMR1; DNA-binding protein that binds to both single- and double- stranded DNA. Binds preferentially to UV-damaged DNA. May be involved in DNA-metabolic processes. (602 aa)
SRO77Putative Rab GTPase-binding protein. (1076 aa)
HAT2Histone acetyltransferase type B subunit 2; Regulatory subunit of the histone acetylase B (HAT-B) complex. The complex acetylates 'Lys-14' of histone H4 which is required for telomeric silencing. (382 aa)
BUB3Bub3p. (373 aa)
SWD2WD-repeat containing protein. (364 aa)
HSV2SVP1-like protein 2; Involved in mitochondrial or peroxisomal functions and amino acid signaling pathways. (595 aa)
ASC1Guanine nucleotide-binding protein subunit beta-like protein; Located at the head of the 40S ribosomal subunit in the vicinity of the mRNA exit channel, it serves as a scaffold protein that can recruit other proteins to the ribosome. Involved in the negative regulation of translation of a specific subset of proteins (By similarity). Plays a role in morphogenesis and pathogenesis. (317 aa)
TUP1Transcriptional repressor TUP1; Represses transcription by RNA polymerase II. Represses genes responsible for initiating filamentous growth such as HWP1, RBT1, RBT2, RBT4, RBT5, RBT7 and WAP1; and this repression is lifted under inducing environmental conditions. Represses also genes which participate in pathogenesis. Crucial component of the response to farnesol. Plays an important role in the regulation of white-opaque switching. (512 aa)
CaO19.7343U4/U6-U5 snRNP complex subunit. (458 aa)
ARC40Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (384 aa)
CaO19.536Chromatin modification protein. (798 aa)
CaO19.4395WD_REPEATS_REGION domain-containing protein. (613 aa)
CaO19.7527Uncharacterized protein. (726 aa)
UTP18Utp18p. (552 aa)
UME1Ume1p. (485 aa)
ENP2Ribosome biosynthesis protein. (750 aa)
CaO19.5131Glucose-induced degradation complex subunit. (720 aa)
CRN1Coronin; Belongs to the WD repeat coronin family. (633 aa)
CaO19.2143Uncharacterized protein. (947 aa)
GLE2RNA export factor. (383 aa)
SEC27Coatomer subunit beta; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (939 aa)
SWD3Swd3p. (383 aa)
CDC20Ubiquitin-protein transferase activating protein. (634 aa)
VPS15Ubiquitin-binding serine/threonine protein kinase. (1537 aa)
CaO19.132Uncharacterized protein. (593 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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