6 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC46	DNA helicase; Belongs to the MCM family. (728 aa)
	MCM3	DNA helicase; Belongs to the MCM family. (878 aa)
	MCM6	DNA helicase; Belongs to the MCM family. (880 aa)
	CDC47	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (781 aa)
	CDC54	DNA helicase; Belongs to the MCM family. (912 aa)
	MCM2	DNA helicase; Belongs to the MCM family. (903 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC46	CDC47	Q59P49	A0A1D8PIE7	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
CDC46	CDC54	Q59P49	A0A1D8PFE6	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC46	MCM2	Q59P49	Q5A034	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC46	MCM3	Q59P49	A0A1D8PHW4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC46	MCM6	Q59P49	A0A1D8PS48	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC47	CDC46	A0A1D8PIE7	Q59P49	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
CDC47	CDC54	A0A1D8PIE7	A0A1D8PFE6	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
CDC47	MCM2	A0A1D8PIE7	Q5A034	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
CDC47	MCM3	A0A1D8PIE7	A0A1D8PHW4	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
CDC47	MCM6	A0A1D8PIE7	A0A1D8PS48	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	DNA helicase; Belongs to the MCM family.	0.999
CDC54	CDC46	A0A1D8PFE6	Q59P49	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC54	CDC47	A0A1D8PFE6	A0A1D8PIE7	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
CDC54	MCM2	A0A1D8PFE6	Q5A034	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC54	MCM3	A0A1D8PFE6	A0A1D8PHW4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
CDC54	MCM6	A0A1D8PFE6	A0A1D8PS48	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM2	CDC46	Q5A034	Q59P49	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM2	CDC47	Q5A034	A0A1D8PIE7	DNA helicase; Belongs to the MCM family.	DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...]	0.999
MCM2	CDC54	Q5A034	A0A1D8PFE6	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM2	MCM3	Q5A034	A0A1D8PHW4	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999
MCM2	MCM6	Q5A034	A0A1D8PS48	DNA helicase; Belongs to the MCM family.	DNA helicase; Belongs to the MCM family.	0.999