STRINGSTRING
RAD50 RAD50 SMC3 SMC3 XOG1 XOG1 STE18 STE18 REC8 REC8 ATP9 ATP9 DCW1 DCW1 DFG5 DFG5 MET6 MET6 PDS5 PDS5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RAD50MRX complex DNA-binding subunit. (1332 aa)
SMC3Structural maintenance of chromosomes protein. (1237 aa)
XOG1Glucan 1,3-beta-glucosidase; Major glucan 1,3-beta-glucosidase required for cell wall integrity. Beta-glucanases participate in the metabolism of beta- glucan, the main structural component of the cell wall. Can also function biosynthetically as a transglycosylase. Functions to deliver glucan from the cell to the extracellular matrix. Does not appear to impact cell wall glucan content of biofilm cells, nor is it necessary for filamentation or biofilm formation. Involved in cell-substrate and cell-cell adhesion. Adhesion to host-cell surfaces is the first critical step during mucosal in [...] (438 aa)
STE18Ste18p. (90 aa)
REC8Rad21_Rec8_N domain-containing protein. (635 aa)
ATP9ATP synthase subunit 9, mitochondrial; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the centr [...] (76 aa)
DCW1Mannan endo-1,6-alpha-mannosidase DCW1; Probable mannosidase required for normal synthesis of the cell wall; Belongs to the glycosyl hydrolase 76 family. (452 aa)
DFG5Mannan endo-1,6-alpha-mannosidase DFG5; Required for normal synthesis of the cell wall and alkaline pH-induced hypha formation. (451 aa)
MET65-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (767 aa)
PDS5Pds5p. (1303 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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