STRINGSTRING
SAS3 SAS3 HHT3 HHT3 PXR1 PXR1 HHT21 HHT21 MNL1 MNL1 GCN5 GCN5 PGK1 PGK1 PHR1 PHR1 PHR2 PHR2 RLM1 RLM1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SAS3Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (805 aa)
HHT3Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
PXR1Protein PXR1; Involved in rRNA-processing at A0, A1 and A2 sites and regulates negatively telomerase; Belongs to the PINX1 family. (276 aa)
HHT21Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
MNL1Transcriptional regulator MNL1; Transcription factor that activates stress response genes via SLE (STRE-like) elements. Required for adaptation to weak acid stress such as acetic acid stress, but seems not involved in the response to heat, osmotic, ethanol, nutrient, oxidative, or heavy-metal stress. Activates a subset of the genes that are repressed by NRG1. (905 aa)
GCN5Histone acetyltransferase. (449 aa)
PGK1Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
PHR1pH-responsive protein 1; Required for apical cell growth and plays an essential role in morphogenesis. May be integral to the pathogenic ability of the organism. (548 aa)
PHR2pH-responsive protein 2; Required for apical cell growth and plays an essential role in morphogenesis. May be integral to the pathogenic ability of the organism (By similarity). (544 aa)
RLM1Rlm1p. (601 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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