10 items (Candida albicans) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MSH6	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1214 aa)
	MUS81	Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (614 aa)
	SMC3	Structural maintenance of chromosomes protein. (1237 aa)
	RAD50	MRX complex DNA-binding subunit. (1332 aa)
	PMS1	ATP-binding mismatch repair protein. (910 aa)
	SPO11	Spo11p. (309 aa)
	MLH3	Mismatch repair protein. (636 aa)
	EXO1	Rad2 family nuclease. (699 aa)
	MSH2	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR). (873 aa)
	MLH1	Mismatch repair ATPase. (717 aa)

Your Current Organism:

Candida albicans

NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EXO1	MLH1	A0A1D8PMZ2	Q59SL0	Rad2 family nuclease.	Mismatch repair ATPase.	0.984
EXO1	MLH3	A0A1D8PMZ2	A0A1D8PFX1	Rad2 family nuclease.	Mismatch repair protein.	0.920
EXO1	MSH2	A0A1D8PMZ2	Q5A102	Rad2 family nuclease.	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR).	0.986
EXO1	MSH6	A0A1D8PMZ2	A0A1D8PFM1	Rad2 family nuclease.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.987
EXO1	MUS81	A0A1D8PMZ2	Q59NG5	Rad2 family nuclease.	Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family.	0.960
EXO1	PMS1	A0A1D8PMZ2	A0A1D8PII6	Rad2 family nuclease.	ATP-binding mismatch repair protein.	0.985
EXO1	RAD50	A0A1D8PMZ2	A0A1D8PJD1	Rad2 family nuclease.	MRX complex DNA-binding subunit.	0.848
EXO1	SMC3	A0A1D8PMZ2	A0A1D8PJK7	Rad2 family nuclease.	Structural maintenance of chromosomes protein.	0.722
EXO1	SPO11	A0A1D8PMZ2	A0A1D8PID6	Rad2 family nuclease.	Spo11p.	0.887
MLH1	EXO1	Q59SL0	A0A1D8PMZ2	Mismatch repair ATPase.	Rad2 family nuclease.	0.984
MLH1	MLH3	Q59SL0	A0A1D8PFX1	Mismatch repair ATPase.	Mismatch repair protein.	0.997
MLH1	MSH2	Q59SL0	Q5A102	Mismatch repair ATPase.	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR).	0.998
MLH1	MSH6	Q59SL0	A0A1D8PFM1	Mismatch repair ATPase.	DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).	0.999
MLH1	MUS81	Q59SL0	Q59NG5	Mismatch repair ATPase.	Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family.	0.800
MLH1	PMS1	Q59SL0	A0A1D8PII6	Mismatch repair ATPase.	ATP-binding mismatch repair protein.	0.999
MLH1	SMC3	Q59SL0	A0A1D8PJK7	Mismatch repair ATPase.	Structural maintenance of chromosomes protein.	0.688
MLH1	SPO11	Q59SL0	A0A1D8PID6	Mismatch repair ATPase.	Spo11p.	0.700
MLH3	EXO1	A0A1D8PFX1	A0A1D8PMZ2	Mismatch repair protein.	Rad2 family nuclease.	0.920
MLH3	MLH1	A0A1D8PFX1	Q59SL0	Mismatch repair protein.	Mismatch repair ATPase.	0.997
MLH3	MSH2	A0A1D8PFX1	Q5A102	Mismatch repair protein.	Mismatch repair ATPase; Component of the post-replicative DNA mismatch repair system (MMR).	0.987