STRINGSTRING
CRZ1 CRZ1 HHT21 HHT21 GCN5 GCN5 PDC11 PDC11 PGK1 PGK1 CaO19.7437 CaO19.7437 ERG11 ERG11 BMT5 BMT5 HHT3 HHT3 CaO19.2092 CaO19.2092 LYS14 LYS14
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CRZ1Transcriptional regulator CRZ1; Transcription factor involved in the regulation of calcium ion homeostasis and required for the maintenance of membrane integrity. Binds to the calcineurin-dependent response element. Plays a role in azole tolerance. (731 aa)
HHT21Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
GCN5Histone acetyltransferase. (449 aa)
PDC11Pyruvate decarboxylase; Belongs to the TPP enzyme family. (567 aa)
PGK1Phosphoglycerate kinase; Belongs to the phosphoglycerate kinase family. (417 aa)
CaO19.7437Acetyltransferase. (307 aa)
ERG11Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol. (528 aa)
BMT5Beta-mannosyltransferase 5; Beta-mannosyltransferase involved in cell wall biosynthesis. Required for beta-1,2-mannose transfer on phospholipomannan. (612 aa)
HHT3Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
CaO19.2092Cystathionine beta-lyase. (404 aa)
LYS14Lys14p. (592 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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