STRINGSTRING
HOS1 HOS1 SMC3 SMC3 HOS2 HOS2 SIN3 SIN3 SNF2 SNF2 HHT3 HHT3 SAS2 SAS2 SET1 SET1 SWD1 SWD1 SET2 SET2 HHF1 HHF1 HHT21 HHT21 GCN5 GCN5 SWD2 SWD2 RPD3 RPD3 SAS3 SAS3 UME1 UME1 SWD3 SWD3 HOS3 HOS3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HOS1Histone deacetylase. (436 aa)
SMC3Structural maintenance of chromosomes protein. (1237 aa)
HOS2Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (454 aa)
SIN3Transcriptional regulator. (1411 aa)
SNF2SWI/SNF catalytic subunit. (1690 aa)
HHT3Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
SAS2Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (352 aa)
SET1Histone-lysine N-methyltransferase, H3 lysine-4 specific; Catalytic component of the COMPASS (Set1C) complex that specifically mono-, di- and trimethylates histone H3 to form H3K4me1/2/3, which subsequently plays a role in telomere length maintenance, transcription elongation regulation and pathogenesis of invasive candidiasis; Belongs to the class V-like SAM-binding methyltransferase superfamily. (1040 aa)
SWD1COMPASS subunit protein. (447 aa)
SET2Histone-lysine N-methyltransferase, H3 lysine-36 specific; Histone methyltransferase that trimethylates histone H3 'Lys- 36' forming H3K36me3. Involved in transcription elongation as well as in transcription repression; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily. (844 aa)
HHF1Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (105 aa)
HHT21Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
GCN5Histone acetyltransferase. (449 aa)
SWD2WD-repeat containing protein. (364 aa)
RPD3Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (480 aa)
SAS3Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (805 aa)
UME1Ume1p. (485 aa)
SWD3Swd3p. (383 aa)
HOS3Histone deacetylase. (713 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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