STRINGSTRING
ACT1 ACT1 TOR1 TOR1 SPO11 SPO11 CaO19.5300 CaO19.5300 STE3 STE3 CaO19.3306 CaO19.3306 SNF1 SNF1 IPP1 IPP1 IME2 IME2 SKP1 SKP1 HHT21 HHT21 REC8 REC8 RIM101 RIM101 HHT3 HHT3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACT1Actin. (376 aa)
TOR1Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family. (2482 aa)
SPO11Spo11p. (309 aa)
CaO19.5300Calnexin. (581 aa)
STE3Ste3p. (417 aa)
CaO19.3306HORMA domain-containing protein. (607 aa)
SNF1Non-specific serine/threonine protein kinase. (618 aa)
IPP1Inorganic pyrophosphatase; Belongs to the PPase family. (288 aa)
IME2Protein kinase. (520 aa)
SKP1SCF ubiquitin ligase subunit; Belongs to the SKP1 family. (164 aa)
HHT21Histone H3.1/H3.2; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
REC8Rad21_Rec8_N domain-containing protein. (635 aa)
RIM101pH-response transcription factor pacC/RIM101; Transcription factor that mediates regulation of both acid- and alkaline-expressed genes in response to ambient pH. At alkaline ambient pH, activates transcription of alkaline-expressed genes (including RIM101 itself) and represses transcription of acid- expressed genes. Specifically recognizes and binds the consensus sequence 5'-CCAAGAA-3'. Required for the control of alkaline pH-induced filamentation (dimorphic switch) and virulence. (661 aa)
HHT3Histone H3.3; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling (By similarity). (136 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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