STRINGSTRING
ACT1 ACT1 GDH2 GDH2 SPO11 SPO11 MEP2 MEP2 GDH3 GDH3 MEP1 MEP1 RAD50 RAD50 REC8 REC8 MSH6 MSH6 PDS5 PDS5 DCC1 DCC1 EXO1 EXO1 DYN1 DYN1 ARC40 ARC40 CDC42 CDC42 MUS81 MUS81
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ACT1Actin. (376 aa)
GDH2NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (1056 aa)
SPO11Spo11p. (309 aa)
MEP2Ammonium transporter. (480 aa)
GDH3Glutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (456 aa)
MEP1Ammonium transporter. (535 aa)
RAD50MRX complex DNA-binding subunit. (1332 aa)
REC8Rad21_Rec8_N domain-containing protein. (635 aa)
MSH6DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (1214 aa)
PDS5Pds5p. (1303 aa)
DCC1Dcc1p. (339 aa)
EXO1Rad2 family nuclease. (699 aa)
DYN1Dynein heavy chain. (4161 aa)
ARC40Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks; Belongs to the WD repeat ARPC1 family. (384 aa)
CDC42Cell division control protein 42 homolog; Involved in hyphal formation, virulence, morphogenesis; Belongs to the small GTPase superfamily. Rho family. CDC42 subfamily. (191 aa)
MUS81Crossover junction endonuclease MUS81; Interacts with EME1 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'-flap structures, D-loops, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication fork intermediates. May be required in meiosis for the repair of meiosis-specific double strand breaks subsequent to single- end invasion (SEI) (By similarity); Belongs to the XPF family. (614 aa)
Your Current Organism:
Candida albicans
NCBI taxonomy Id: 237561
Other names: C. albicans SC5314, Candida albicans SC5314
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